- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Liver Disease Diagnosis and Treatment
- Adolescent Sexual and Reproductive Health
- Liver Diseases and Immunity
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic function and diabetes
- Hepatitis B Virus Studies
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Sex work and related issues
- Hepatitis C virus research
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Medication Adherence and Compliance
- Homelessness and Social Issues
- Celiac Disease Research and Management
- HIV/AIDS Impact and Responses
- Metabolism and Genetic Disorders
- Viral-associated cancers and disorders
- Diabetes and associated disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Drug Transport and Resistance Mechanisms
Shiraz University of Medical Sciences
2016-2025
Jahrom University
2024
Jahrom University of Medical Sciences
2024
Abstract Islets transplantation, as a treatment of type 1 diabetes, faces challenges, including the loss islets in process isolation and pre-transplantation due to cellular stresses-induced apoptosis. Accordingly, optimization culture plays decisive role transplantation success. In this study, we evaluated effect nobiletin on cultured human islets. Isolated were treated by different concentrations for 24 72 hours. Then, viability, apoptosis, insulin C-peptide secretion, apoptosis markers...
As a concentrated epidemic, human immunodeficiency virus (HIV) is spreading rapidly in one or more groups Iran, but the general population its prevalence relatively low. Female sex workers (FSWs) and their partners are at greater risk for HIV infection. To determine of sexually transmitted infections (STIs) including gonorrhoea, Chlamydia, herpes simplex type 2 syphilis among FSWs. We conducted cross-sectional study 278 FSWs Shiraz, by using respondent-driven sampling, from June to March...
Liver transplantation requires lifelong immunosuppression, which has significant psychological and physiological implications. While depression anxiety are prevalent among transplant recipients, their potential relationship with immune tolerance remains unclear. This study aims to evaluate the association between depression, anxiety, in liver recipients. cross-sectional included 179 adult categorized as tolerant (n=49) non-tolerant (n=130) based on immunosuppressive status. Depression levels...
This quasi-experimental, before–after study was designed to assess the effect of an educational intervention on knowledge and attitudes about sexually transmitted infections, HIV preventive behaviours among female sex workers in Shiraz, Iran. A single-group pre–post test design used done between August December 2009. The participants were 80 recruited from three drop-in centers with stratified random sampling. Pre-intervention assessed by interview a standard questionnaire. consisted...
Islet transplantation is considered as a promising approach in the treatment of diabetes type 1. In this regard, optimal culture pancreatic islets success transplantation. present study, effect olesoxime, an antiapoptotic substance, was evaluated on human islet culture.The were isolated by mechanical and enzymatic techniques. After overnight recovery, treated different concentrations olesoxime for 24 72 h. Then, they examined terms viability, apoptosis, genes proteins expression including...
Clinical laboratories are significant generators of infectious waste, including microbiological materials, contaminated sharps, and pathologic wastes such as blood specimens products. Most waste produced in can be disposed the general solid stream. However, improper management mixing with handling or storage, could lead to disease transmission. The aim this study was assess processes used at clinical Shiraz, Iran. One hundred nine participated In cross sectional study, Data collection by...
Introduction: HIV infection remains as a major challenge facing medical sciences in the world today. Mucocutaneous manifestation was first observed patients with HIV/AIDS early 1980s. The aim of this study to identify various skin manifestations based on making careful clinical observations and performing necessary tests. Materials Methods: A total 240 whose disease diagnosed using WB ELISA tests, dermatologic were older than 18 years, participated study. These had referred voluntary...
Liver diseases in children and adolescents are a significant arising public health issue should be surveyed from different dimensions (clinical para-clinical, psychological, socio-economic) diverse populations. Shiraz Transplant Center, Shiraz, Iran is the only center for pediatric liver transplantation its pre-operative evaluations. This provides unique valuable situation studying this vulnerable population. The Pediatric Cirrhosis Cohort Study (SPLCCS) was established to assess cirrhotic...
Crigler-Najjar syndrome (CNS) is a rare autosomal recessive disorder characterized by impaired bilirubin metabolism, leading to neurotoxic unconjugated accumulation. Liver transplantation remains the only effective treatment, highlighting need for novel diagnostic and therapeutic approaches. Long non-coding RNAs (lncRNAs) have emerged as potential biomarkers in various diseases, including cancer. This study aimed evaluate expression of lncRNAs HOTTIP HOTAIR CNS patients healthy controls,...
Abstract Introduction Roux‐en‐Y choledochojejunostomy and duct‐to‐duct (D‐D) anastomosis are biliary reconstruction methods for liver transplantation. However, there is a controversy over which method produces better results. We have compared the outcome of D‐D vs. hepaticojejunostomy in patients with primary sclerosing cholangitis who had undergone transplant Shiraz Organ Transplant Center. Materials The medical records 405 ( PSC ) from 1996 to 2015 were reviewed. Patients divided into two...
Background: Medication adherence is a dynamic and complex behavioral process, which strongly influenced by personal, social environmental factors.Objectives: To determine the prevalence factors affecting non-adherence to medication among HIV-infected patients.Methods materials:Design: A cross-sectional study.Setting: Voluntary Counseling Testing Center (VCT), Shiraz, Fars province, in South of Iran.Patients: Among HIV-positive patients who received anti-retroviral therapy, 214 adult were...
HIV/AIDS not only affects the patients, but also their entire family. This study aimed to assess impacts of patients’ and spouses’ anxiety depression on quality life (QoL) at dyadic level. A total 120 serodiscordant husband-wife dyads from voluntary counselling testing center in Shiraz, Iran, were involved this February June 2015. The WHOQOL-BREEF, CESD-10, Beck Anxiety Inventory instruments used, respectively, QoL, depression, scores participants. actor-partner interdependence model (APIM)...
Background: Metabolic syndrome (MetS) is a set of conditions that occur together and increase the risk cardiovascular disease. Previous studies have linked gluten-free diet (GFD) to obesity MetS in some populations. However, others suggested weight gain usually regulated only underweight individuals with celiac disease (CD). Owing lack sufficient data importance GFD controlling disease, we surveyed prevalence its components before after year patients referred main clinic southern Iran....