We and others have reported that senescence onset is accompanied by genomic instability evident several defects, such as aneuploidy or erroneous mitosis features. Here, we report these defects also appear in young cells upon oxidative insult. provide evidence errors could be the consequence of stress (OS)- either exogenous senescence-associated - overriding spindle assembly checkpoint (SAC). Young treated with Η2Ο2 well older fail to maintain mitotic arrest presence poisons a significant...

The aim of this article is to evaluate optical characteristics, such as the intrinsic conversion efficiency and inherent light propagation three polymethyl methacrylate (PMMA)/methyl (MMA) composite ZnCuInS/ZnS (core/shell) nanocrystal flexible films. concentrations these were 100 mg/mL, 150 250 respectively. Composite films prepared by homogeneously diluting dry powder quantum dot (QD) samples in toluene subsequently mixing with a PMMA/MMA polymer solution. absolute luminescence (AE) was...

The aim of the present study was to propose a comprehensive method for positron emission tomography (PET) scanners image quality assessment, by simulation thin layer chromatography (TLC) flood source with previously validated Monte Carlo model.We used GATE package (GEANT4 application tomographic emission) and reconstructed images were obtained using software reconstruction (STIR), cluster computing. PET scanner in this General Electric Discovery-ST (USA). plane that assessment TLC plate,...

Background: The aim of the present study was to assess upper information content bound positron emission tomography (PET) images, by means capacity (IC). Methods: Geant4 Application for Tomographic Emission (GATE) Monte Carlo (MC) package used, and reconstructed images were obtained using software tomographic image reconstruction (STIR). case assessment General Electric (GE) Discovery-ST PET scanner. A thin-film plane source aluminum (Al) foil, coated with a thin layer silica...

Abstract Coronary angiography and percutaneous coronary intervention (PCI) procedural details in swine are similar to those performed humans, since their heart anatomy closely resembles. However, only a few detailed descriptions of the procedure available, containing notable differences. We present feasible reproducible protocol for interventions porcine experimental models, utilizing ultrasound-guided femoral approach. Nine female pigs were studied explore feasibility superficial arterial...

Objective The aim of this study was to propose a novel method for image quality assessment in PET scanners through estimation the modulation transfer function (MTF) plane source. simulation implemented using previously validated Monte-Carlo model. A comparison proposed with more traditional technique, based on line source, also performed. Materials and methods Geant4 application tomographic emission (GATE) package used model development, reconstructed images were obtained software...

Machine learning is a domain highly influenced by the rapid evolution of cloud computing and has reached maturity point where plethora data processing capabilities now widely available. The aim present study to investigate potential for building common platform support direct end-user application machine algorithms across diverse scientific areas, emphasizing not only suitability appropriate tools, but also how results can be disseminated utilized in shared environment. Three case studies...

According to the WHO, front-of-pack nutrition labeling provides simplified information in form of symbols, colors or words that can help consumers understand nutritional quality food, thus leading them healthier food choices. It is considered utmost importance explore knowledge and understanding about this labeling. The aim study was investigate perceptions Greek response five different labels (FoPLs): Multiple Traffic Lights, Health Star Rating System, Guideline Daily Amounts, Warning...

The aim of this study was to develop a Monte-Carlo model that can be used for the optimization positron emission tomography (PET) procedures and image quality metrics. This developed using Monte Carlo package Geant4 application tomographic (GATE) software reconstruction (STIR) with cluster computing obtain reconstructed images. PET scanner in General Electric Discovery-ST (US). GATE validated by comparing results obtained accordance National Electrical Manufacturers Association...

The role of nutrition in the management asthma obese patients is increasing interest due to their limited response inhaled corticosteroids. Some studies note that through diet and lifestyle, there can be an improvement control. aim present study was investigate adherence Mediterranean Diet its association with severity quality life bronchial asthma. This a cross-sectional 85 (70.6% female), mean age 57 years, from General University Hospital Larissa and, more specifically, outpatient clinic....

Abstract Background Strategies to reduce salt intake are encouraged be implemented in parallel with those that aim ensure iodine adequacy at the population level. The of present study was assess and compare knowledge, attitudes behaviours related among students Europe Asia. Methods A multicentre cross-sectional conducted 2459 university total (42.7% males, median age 21 years) from four countries two Data were collected use a self-administered questionnaire, univariate multivariate...

Background and aim Excessive intake of sugars energy from drinks has been postulated to increase the risk obesity, which may in turn be associated with mental health disorders. In addition, excessive intakes alcohol caffeine co-occur psychiatric The purpose present pilot study was estimate energy, sugar, caffeine, through consumption patients schizophrenia affective disorders assess potential differences drink between two Methodology current included 89 outpatients (n = 36) 53) attending...

The elderly constitute a vulnerable group for increased anxiety and poor diet during the COVID-19 pandemic. There is limited research on levels of COVID-19-related dietary habits including supplementation practices among very in Greece. A cross-sectional survey was conducted 364 non-institutionalized (65-74 y) (≥75 living northern Greece, with aim to investigate use supplements their association other factors, particularly anxiety. Levels were assessed Coronavirus Anxiety Scale (CAS-5)....

Nutrition information is becoming more urgent than ever so that consumers can make informed choices when buying food. This study aimed to investigate consumers' perceptions and behavior of the front-of-pack label (FOPL), between two specific labeling systems, Nutri-Score Guideline Daily Amounts (GDA). a post hoc analysis data from previous, extensive cross-sectional conducted April 2021 June 2021. A total 510 participants were included in study, whom 49.6% women. Participants' assessed nine...

Despite the lack of evidence-based guidance on supplement use for prevention and treatment COVID-19, consumption dietary supplements has been shown to increase in many countries.

It is well known that the luminescence efficiency of single crystals affected by external parameters, such as environmental temperature, especially in harsh environments. Due to this, it worth examine influence temperature on output single-crystal scintillators. In this study lutetium aluminum garnet (Lu3Al5O12:Ce-LuAG:Ce) was examined, against previously published data for cadmium tungstate (CdWO4) and calcium fluoride doped with europium (CaF2:Eu) crystals. Experiments were carried using a...

The aim of the present study was to propose a comprehensive method for PET scanners image quality assessment, by simulation thin layer chromatography (TLC) flood source with previous validated Monte-Carlo (MC) model. model developed using GATE MC package and reconstructed images were obtained STIR software, cluster computing. scanner simulated GE Discovery-ST. TLC immersed in 18F-FDG bath solution (1MBq) order assess quality. influence different scintillating crystals on scanner's quality,...

The aim of the present study was to assess contrast noise ratio (CNR) PET scanners through a thin layer chromatography (TLC) plane source. source simulated using previously validated Monte Carlo model. model developed by GATE MC package and reconstructed images obtained with STIR software for tomographic image reconstruction. scanner GE DiscoveryST. A consisted TLC plate, silica gel on aluminum (Al) foil substrates, immersed in 18F-FDG bath solution. Image quality assessed terms CNR. CNR...

Background: Despite the lack of evidence-based guidance on supplement use for prevention and treatment COVID-19, consumption dietary supplements has been shown to increase in many countries. Objective: This study aimed explore among undergraduate students. Methods: An online cross-sectional survey was conducted between May June 2021, involving a total 536 participants (57.8% female) aged 18-30 years two university towns central northern Greece. Two validated questionnaires were used...

The aim of the present study was to assess image quality PET scanners through a thin layer chromatography (TLC) plane source. source simulated using previously validated Monte Carlo model. model developed by GATE MC package and reconstructed images obtained with STIR software for tomographic reconstruction. scanner GE DiscoveryST. A consisted TLC plate, silica gel on aluminum (Al) foil substrates, immersed in 18F-FDG bath solution (1MBq). Image assessed terms modulation transfer function...

The fast developments and ongoing demands in radiation dosimetry have piqued the attention of many software developers physicists to create powerful tools make their experiments more exact, less expensive, focused, with a wider range possibilities. Many toolkits, packages, programs been produced recent years, majority them available as open source, access, or closed source. This study is mostly focused present what are Monte Carlo developed over implementation treatment, dosimetry, nuclear...

The aim of the present study was to investigate information content positron emission tomography (PET) images. We used GATE Monte Carlo package (GEANT4 application for tomographic emission) and reconstructed images, obtained using software image reconstruction (STIR). case investigation PET images General Electric Discovery-ST (USA) scanner. A thin film plane source aluminum (Al) foil, coated with a layer silica fluorodeoxyglucose (18F-FDG) bath distribution (1 MBq) in simulation signal...

The aim of the present study was to assess image quality PET scanners through a thin layer chromatography (TLC) plane source. source simulated using previously validated Monte Carlo model. model developed by GATE MC package and reconstructed images obtained with STIR software for tomographic reconstruction, cluster computing. scanner in this GE DiscoveryST. A consisted TLC plate, silica gel on aluminum (Al) foil substrates, immersed 18F-FDG bath solution (1MBq). Image assessed terms...