Background: The emergence of antibiotic resistance among bacterial pathogens in the hospital and community has increased concern to health-care providers due limited treatment options. Surveillance antimicrobial (AMR) frequently isolated causing severe infections is great importance. data generated will be useful for clinicians decide empiric therapy on local epidemiological profile agents. This study aims monitor distribution pathogen their susceptibility pattern commonly used Materials...

Abstract Background: Bloodstream infections (BSI) due to opportunistic microbes in the coronavirus disease 2019 (COVID-19) pandemic lead high morbidity and mortality among hospitalized patients. Thus, it is vital find out risk factors of BSI learn ways mitigate it. Aim: The aim this study was evaluate important pathogens assess role rigid infection control program deal with issue. Methods: A prospective, cross-sectional performed for 6 months on 150 patients admitted both COVID-19...

Avicennia marina is a commonly found mangrove species in coastal regions, and known for its medicinal properties. In this study, the antibacterial antifungal activities of ethanolic extract leaves were evaluated against MDR microorganisms. The antimicrobial activity was assessed range bacterial strains, including Salmonella sp. (MDR), Klebsiella Pseudomonas Acinetobacter Staphylococcus aureus as well fungal strain Candida albicans (ATCC 10231), parapsilosis 22019). results showed that leaf...

At present, multidrug-resistant (MDR) fungal species have become widespread worldwide, which leads to high morbidity and mortality. As of now, only a few antifungal agents are coming up in the pharmaceutical industry. This may lead threat humanity for their survival. In this study, we explored possible action ethanolic extract Azadirachta indica, seeds against MDR ATCC strains Candida species. The showed activities with MIC varied between 0.76 1.56 mg/mL both Thus, indica seed is an...

Antimicrobial resistance (AMR) is a critical global health concern under the present clinical scenario due to overuse and misuse of antibiotics in both medical agricultural sectors. Passiflora foetida, commonly known as wild maracuja or stinking passion flower belongs Passifloraceae family native tropical subtropical regions Asia, Africa, Australia, America. In this study, we aimed explore potential antimicrobial efficacy foetida leaf extract against MDR bacteria American Type Culture...

Indian senna (Cassia angustifolia) is a perennial shrub belonging to the family Fabaceae. contains flavonoids, pinnitolos (polyols), acidic polysaccharides, and mineral substances. It also two types of glucosides known as sennosides A B other compounds, including myricyl alcohol, anthraquinone derivatives, galactose, arabinose, rhamnose, galacturonic acid, chrysophanic salicylic resin, mannitol. The antifungal activity extract was assessed against fungal strains, Candida albicans...

Antimicrobial drug resistance is gradually increasing throughout the globe, and there practically no newer antimicrobial agent coming soon. Plant secondary metabolites are well known for their various biological activities, few studies targeting mangrove plants. Thus, in this study, we aim to assess effectiveness of ethanolic extract flowers Avicennia marina, a commonly found species coastal regions, against multi-drug resistant (MDR) microorganisms. The study focused on evaluating extract's...

Antimicrobial resistance is a global problem that jeopardizes the efficient use of modern medicine and state world's health. The effectiveness traditional antifungals used to treat fungal infections has declined, increasing mortality. Following exposure antifungal medications, acquired mechanisms can lead development currently available medicines. Invasive have few treatment choices, patients who are most at risk frequently other co-morbid conditions, such as immunosuppression. This made...

Ceftolozane/tazobactam is a novel antimicrobial agent with activity against Pseudomonas aeruginosa and other common Gram-negative pathogens. In this study, we determined the susceptibility for total of 149 clinical isolates P. most commonly used antimicrobials including new ceftolozane/tazobactam (C/T). Broth microdilution was performed to determine minimum inhibitory concentration various C/T. Among β-lactam/β-lactamase inhibitor, overall 67%, 55% 51% C/T, Piperacillin/Tazobactam (P/T)...

Background: Scrub typhus is an acute infectious disease, caused by Orientia tsutsugamushi. It endemic to a geographically distinct region of Japan, Taiwan, China, and South Korea, known as the tsutsugamushi triangle, well in Nepal, Pakistan, Papua New Guinea. In India, incidence this disease varies from 4-46% with high morbidity mortality. Methods: cross-sectional study at tertiary care hospital Kolkata, India we analysed ferritin blood levels along different demographic laboratory test...

Autoimmune diseases are chronic hypersensitive that occur due to an inability of the immune system recognize self-antigens as part its system. Antinuclear autoantibodies (ANA) antibodies target proteins located in nucleus, mitotic spindle, nuclear membrane, and cytoplasmic substructures. Detection ANA is done using either ANA-IIF or by ELISA method; latter might be slightly more sensitive compared but specificity however low. patterns such nuclear, cytoplasmic, can important clinical...

Background: Antimicrobial Resistance is a major concern.The rising trend has created nuisance affecting the global economy and sustainable development Goals.Data about antimicrobial resistance therefore might help in knowing trends acting.Critical care patients are prone to develop nosocomial infections.A brief knowledge this would judicious use of antibiotics.This multicentric study was undertaken understand prevalence pattern, Multidrug (MDR)/ Extensive Drug (XDR)/Pan-drug (PDR), among GNB...

This study aimed to determine the antibacterial effect of extract Nymphaea alba petals, and if activities are present then Minimum Inhibitory Concentration (MIC) is determined. Currently multidrug resistant bacteria a major concern for clinicians as most conventional antibiotics do not work against MDR strains infections with increasing day by day, many resulting in death. focused mainly on activity ethanol extract. Our showed that crude significantly effective Pseudomonas aeruginosa...

Antinuclear antibodies (ANA) are significant biomarkers that used to detect and classify autoimmune connective tissue disorders more efficiently. This paper provides a thorough overview of all the ANA profiling procedures, their testing advancements, clinical significance, future directions. study aimed analyze profiles along with prevalence specific in patients presumed have been diagnosed an Eastern Indian tertiary care hospital. The results were correlated demographic data conclude. 48...

Due to increasing drug resistance bacterial isolates in hospitals, morbidity and mortality are gradually throughout the globe. Newer antibiotics also not coming up as most manufacturing industries reluctant manufacture due low profit. In this context, we have determine antimicrobial activities of other common chemical agents. Thus experiment, studied L-asparagine- an amino acid with various biological find out its activity if any. We were particularly interested MDR bacteria study....

Only recently microbial impurity of beach sand has become an essential issue, particularly during the COVID-19 and in post-Covid period when a large number beachgoers are infected not only by virus but also with other microbes. Besides bacterial viral microbes, fungal contamination been studied detail recent past. Although few Candida spp. have isolated from sand, growths common pathogenic like albicans so far. In this study, we used two species – parapsilosis to observe their growth...

Background: In critically ill and immunocompromised patients, diagnosing invasive aspergillosis (IA) is crucial. This study focuses on theGalactomannan (GM) Antigen Test. The categorizes GM-positive patients into two groups based bronchoalveolar lavage fluid GM levels: Group 1 (GM index >1.5) 2 >0.5-1.5). Aim: aims to investigate the association between levels in clinical outcomes IA specifically focusing mortality rates. Additionally, explores role of C-reactive protein (CRP)...

This study aims to investigate the presence of Free-Living Amoebae (FLA), particularly Acanthamoeba spp., in diverse water systems and body fluids within a hospital. Water fluid samples were collected from various locations. Cultivation FLA was performed using Non-Nutrient Agar (NNA) culture with Escherichia coli, microscopic observations after staining. Microscopic revealed spp. pre-dialysis tank dental flush samples. The identification specific sources underscores importance continuous...

HLA-B27 test is generally positive in spondyloarthritis (SpA) and ankylosing spondylitis (AS). Several anomalous laboratory results are frequently found HLA-B27-positive patients. In this study, we intended to evaluate two groups of patients- one group belonging the 13-40 years age another 41-71 group. The rationale partition was based on when AS first emerged disease set up for quite a few respectively. We anticipate alterations several familiar outcomes between these groups. After our...

Multi-drug resistance is a major concern to medical science across the globe. The inability of most drugs destroy different pathogenic bacteria and fungi demands use natural products like phytochemicals treat various infections. At this juncture, Cinnamomum verum an active agent against fungi. C. or true cinnamon widely used as spice. It has several medicinal values accepted traditional medicine. Cinnamaldehyde compound that responsible for its antimicrobial activity. In study, minimum...

In this study we analysed campylobacteriosis cases in a tertiary care hospital of India to find out is an isolated disease or allied with comorbidities elderly people. all the four cases, acute gastroenteritis by Campylobacter appears be contributory condition besides other associated diseases. Perceptive link between and crucial for effective prevention, early detection, thorough care, populations underlying health problems.