A5063986321- Cerebral Palsy and Movement Disorders
- Muscle activation and electromyography studies
- Neonatal and fetal brain pathology
- Stroke Rehabilitation and Recovery
- EEG and Brain-Computer Interfaces
- Botulinum Toxin and Related Neurological Disorders
- Advanced Neuroimaging Techniques and Applications
- Motor Control and Adaptation
- Infant Development and Preterm Care
- Tactile and Sensory Interactions
- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- Neurological disorders and treatments
Boys Town
2020-2023
Boys Town National Research Hospital
2020-2023
University of Nebraska Medical Center
2020
Nebraska Medical Center
2020
Abstract Objective It is widely believed that the perinatal brain injuries seen in youth with cerebral palsy (CP) impact neuronal processing of sensory information and production leg motor actions during gait. However, very limited efforts have been made to evaluate connection between neural activity within sensorimotor networks altered spatiotemportal gait biomechanics CP. The objective this investigation was use magnetoencephalographic (MEG) imaging biomechanical analysis probe connection....
Our prior magnetoencephalographic (MEG) investigations demonstrate that persons with cerebral palsy (CP) have weaker somatosensory cortical activity than neurotypical (NT) controls, which is associated reduced muscular strength and mobility. Power training can improve lower extremity isokinetic strength, power, walking performance of youth CP. Potentially, these clinically relevant improvements are partially driven by changes in processing. The objective this investigation was to determine...
To utilize magnetoencephalographic (MEG) brain imaging to examine potential changes in sensorimotor cortical oscillations after therapeutic power training individuals with cerebral palsy (CP).Cohort.Academic medical center.Individuals CP (N=11; age=15.9±1.1 years; Gross Motor Function Classification System I- III) and neurotypical controls (NTs; N=16; age=14.6±0.8 years).Participants underwent 24 (8 weeks; 3 days a week) sessions of high-velocity lower extremity on leg press. The NTs single...
Cerebral Palsy (CP) is the most common neurodevelopmental motor disability, resulting in life-long sensory, perception and impairments. Moreover, these impairments appear to drastically worsen as population with CP transitions from adolescents adulthood, although underlying neurophysiological mechanisms remain poorly understood. We began address this knowledge gap by utilizing magnetoencephalographic (MEG) brain imaging study how amplitude of spontaneous cortical activity (i.e., resting...
Brain-derived neurotrophic factor (BDNF) plays a critical role in the capacity for neuroplastic change. A single nucleotide polymorphism of BDNF gene is well known to alter activity-dependent release protein and may impact Numerous studies have shown altered sensorimotor beta event-related desynchronization (ERD) responses youth with cerebral palsy (CP), which thought be directly related motor planning. The objective current investigation was use magnetoencephalography (MEG) evaluate whether...
There are numerous clinical reports that youth with cerebral palsy (CP) have proprioceptive, stereognosis and tactile discrimination deficits. is a growing consensus such altered perceptions in this population attributable to the aberrant somatosensory cortical activity seen during stimulus processing. It has been inferred from these results CP likely do not adequately process ongoing sensory feedback motor performance. However, conjecture yet be tested. Herein, we address knowledge gap...