Objectives Elevated levels of matrix metalloproteinase-9 (MMP-9) in both serum and cerebrospinal fluid have been observed patients diagnosed with cysticercus granuloma. These elevated significantly contribute to the onset symptoms, such as active seizures, neurocysticercosis (NCC). This study aimed compare correlate MMP-9 between NCC cases control subjects. Materials Methods In this prospective case-control study, 45 symptomatic 30 controls were enrolled. Serum measured using a commercially...

The aim of this observational study was ultrasound evaluation peripheral nerves cross-sectional area (CSA) in subjects with probable diabetic sensorimotor neuropathy (DPN). CSA analyzed reference to clinical and nerve conduction study's (NCS) parameters for early diagnosis pattern involvement.A total 50 patients DPN due Type 2 diabetes age-matched healthy controls underwent sonographic examinations ulnar at the lower arm, median proximal carpal tunnel, common peroneal fibular head, tibial...

Dear Sir, A 22-year-old man presented to us with a history suggestive of chronic meningitis in the form fever and headache for last 2 months along occasional episodes vomiting weeks. He had dysarthria 10 days some difficulty swallowing. Five before admission, patient developed weakness all four limbs bladder–bowel involvement, leading him being bed-bound state next 3 days. On examination, was conscious oriented dysarthria. Cranial nerve examination normal, except sluggish response gag...

To study the prevalence of psychiatric co-morbidity in patients chronic daily headache (CDH) and compare efficacy treatment between various type associated with co-morbidity.Prospective case control cohort study, 92 consecutive CDH meeting eligibility criteria. The diagnosis subtypes was made according to IHS Age, sex, educational, marital socioeconomic status, matched controls were also selected. Patients evaluated Mini International Neuropsychiatric Interview (MINI) scale at time enrolment...

Pure neuritic leprosy (PNL) accounts for 5% to 10% of patients who usually present with asymmetrical neuropathy in the absence lepra bacilli on slit-skin smears. However, nerve biopsies PNL lack appropriate categorization current immunologic terms. We aimed classify according immune spectrum and assess role histologic classification treating PNL. Patients from two tertiary care referral centres were enrolled this incident case study. presenting mononeuropathy multiple mononeuropathies...

Background Migraine is a risk factor for thiamine deficiency and Wernicke's encephalopathy (WE). WE highly underdiagnosed condition. The misdiagnosis associated more with early or mild WE. interrelation between migraine unknown Case reports Here, we report two female patients chronic migraine. During examinations, also noted clinical signs pertinent diagnosis of Both had low blood level. Intravenous supplementation led to the improvement both headaches. Discussion Nausea, vomiting, anorexia...

Background: The most common form of movement disorder presented in children with cerebral palsy is spasticity, and dynamic equinus the spastic ankle deformity. Botulinum toxin (BT) injection now an established first-line treatment for focal spasticity. Aim: To assess effects BT casting diagnosed diplegia. Setting design: A prospective randomized controlled trial was conducted among patients aged 2-12 years diplegia, attending general outpatient department admitted to indoor facility...

Our aim was to observe frequency of cranial autonomic symptoms (CAS) in migraineurs (primary) and its relation with laterality headache or other factors, if any.Migraine episodes have headaches without aura, sometimes associated systemic nervous system symptoms. Primarily presence suggests diagnosis TACs. But many studies reported ranging from 26% 80% migraine patients.Consecutive patients attending our clinic were included study. Presence CAS recorded respect ocular, nasal, facial aural...

Abstract Background Stroke-associated pneumonia (SAP) is an important cause of poststroke morbidity and mortality. Several clinical risk scores predict the SAP. In this study, we used A2DS2 score (age, atrial fibrillation, dysphagia, sex, stroke severity) to assess SAP in patients admitted with acute stroke. Methods A high (5–10) a low (0–4) was assigned neurology ward. Univariate binary logistic regression analysis performed find strength association score. Results There were 250 which 46...

Background: Stroke leads to impairment in upper extremity function and hence performance of activities daily living. The studies that emphasize the effects PNF (Proprioceptive Neuromuscular Facilitation) acute stroke are still lacking. Aim: In this study we aim investigate exercises on stroke. Methods: Total 35 patients were recruited from OPD Dr. Ram Manohar Lohia Institute Medical Sciences, Lucknow. Written informed consent was obtained their legal relatives. Patients given for scapula...

Pradeep Kumar Maurya, DM⇑, Mayur Deepak Thakkar, MD, Dinkar Kulshreshtha, DM, Ajai Singh, DM and Anup Thacker, Corresponding Author: Department of Neurology, Dr. Ram Manohar Lohia Institute Medical Sciences, Lucknow 226010 INDIA, Email: pkm730{at}gmail.com

Acute encephalitis syndrome (AES) is a major health problem in developing countries including India. Neuronal injury attributed to direct toxicity from pathogens and proinflammatory cytokines. In this study, we assessed cytokine levels serum cerebrospinal fluid (CSF), their correlation with clinical symptoms. our patients AES for duration of less than 2 weeks underwent brain imaging followed by CSF analysis routine parameters viral studies. We interleukin (IL)-6, IL-10, regulated on...

A diagnosis of mononeuropathy multiplex (MM) requires detailed evaluation to determine etiology. We performed nerve biopsy on patients with MM in whom the etiology could not be established via other investigations.Sixty-eight seen between January 2013 and June 2014 underwent diagnostic evaluation. Those investigations failed establish an biopsy.A leprosy was confirmed 14 highly probable 17 others. Eleven had vasculitic neuropathy, 1 patient there were amyloid deposits biopsy.In 43 68 Indian...

Learning point for clinicians Wilson’s disease is a disorder of copper metabolism, primarily affecting the liver and brain. Atypical clinical presentation delayed or misdiagnosis not uncommon at initial stage. Primary care physician should be aware about varied manifestation this potentially treatable to avoid progression disability. A 35 years male presented with 4 year history predominant psychiatric symptoms in form impulsive behaviour initially later developed delusion, visual...

Abstract Pathological and experimental studies indicate the existence of a “penumbra” progressive tissue damage edema in regions immediately surrounding hematoma patients intracerebral hemorrhage (ICH). This zone oligemia ICH has potential for perfusion recovery. Improved understanding pathophysiology perilesional blood flow changes brain injury after may result improved treatment strategies. The aim was to study by deficit (PD) measured single-photon emission computed tomography (SPECT)...

The artery of Percheron is a rare anatomic variant supplying the thalamus and rostral midbrain. Infarct in this territory results wide array neurological signs symptoms causing diagnostic dilemma management issues. We describe clinical presentations three cases admitted evaluated for diagnosed as percheron infarct after brain imaging. In one patient, etiology turned out to be infective while other two patients had cerebrovascular accident secondary dilated cardiomyopathy hyper homcystinimea...

Background: Intracerebral haemorrhage (ICH) accounts for 15-20% of all strokes and is associated with significant morbidity mortality. The present study was done to assess the risk factors ICH determine responsible poor outcome in ICH.Methods: Consecutive patients were assessed modifiable non-modifiable factors, followed by detailed examination emphasis on score CT scan findings.Results: There 200 ICH; 108 males 92 females. prevalence maximum age group 61-70 years (34%). Hypertension 68%...