A5034454433- Osteoarthritis Treatment and Mechanisms
- Pharmacological Effects of Natural Compounds
- Ferroptosis and cancer prognosis
- Natural product bioactivities and synthesis
- Rheumatoid Arthritis Research and Therapies
- Allergic Rhinitis and Sensitization
- Advanced Fiber Laser Technologies
- Forensic Toxicology and Drug Analysis
- Mechanical and Optical Resonators
- Medicinal Plants and Bioactive Compounds
- Phytochemical and Pharmacological Studies
- Pharmacological Effects of Medicinal Plants
- Cannabis and Cannabinoid Research
- Inflammatory mediators and NSAID effects
- Ginseng Biological Effects and Applications
- Influenza Virus Research Studies
- Inflammatory Bowel Disease
- Cancer, Lipids, and Metabolism
- Circular RNAs in diseases
- Advanced Fiber Optic Sensors
- Biomarkers in Disease Mechanisms
- Fungal Biology and Applications
- Phytochemistry and Bioactive Compounds
- Asthma and respiratory diseases
- Drug Transport and Resistance Mechanisms
Chengdu University of Traditional Chinese Medicine
2023-2025
Union Hospital
2021
Jilin University
2021
Soochow University
2019-2020
Second Affiliated Hospital of Soochow University
2019-2020
Baylor College of Medicine
2011
Abstract Ferroptosis, an iron‐dependent cell death characterized by lethal lipid peroxidation, is involved in chronic obstructive pulmonary disease (COPD) pathogenesis. Therefore, ferroptosis inhibition represents attractive strategy for COPD therapy. Herein, we identified natural flavonoid scutellarein as a potent inhibitor the first time, and its underlying mechanisms of COPD. In vitro, anti‐ferroptotic activity was investigated through CCK8, real‐time quantitative polymerase chain...
Echinatin is an active ingredient in licorice, a traditional Chinese medicine used the treatment of inflammatory disorders. However, protective effect and underlying mechanism echinatin against acute lung injury (ALI) still unclear. Herein, we aimed to explore echinatin-mediated anti-inflammatory effects on lipopolysaccharide (LPS)-stimulated ALI its molecular mechanisms macrophages. In vitro , markedly decreased levels nitric oxide (NO) prostaglandin E2 (PGE 2 ) LPS-stimulated murine MH-S...
Abstract The properties of the non-trivial quantum state in an all-optical environment come mainly from higher-order Quantum electrodynamics (QED) effect, which remains one few unverified predictions this theory due to its weak signal. Here, we propose a scheme specifically designed detect vacuum, where tightly focused pump laser interacts with optical frequency comb (OFC) resonant cavity. When OFC pulse passes through vacuum polarized by high-intensity laser, carrier and envelope change....
Curcumin is the main active component of Curcuma longa,which has a variety biological activities and pharmacological properties.Clinical studies have shown that curcumin its derivatives can improve pathological progress osteoarthritis. The mechanism mainly includes enhancing activity antioxidant enzymes,inhibiting oxidative stress,and protecting cartilage from damage;blocking inflammation-related signal pathways,reducing production inflammatory factors,and reducing inflammation;playing role...
Abstract Osteoarthritis (OA) is a common degenerative disease and affect millions of people. Resveratrol coumarin compound refined from traditional Chinese medicines with potential anti-inflammatory ability. This study aimed to evaluate protective effects resveratrol in human OA chondrocytes. The chondrocytes were isolated patients. CCK-8 method was used explore the optimal dose for chondrocyte. Next, we PCR Western-blot assess relative mRNA protein expression IL-1β group. We further...
Abstract The authors have withdrawn this preprint due to author disagreement.