A5005643110- Wheat and Barley Genetics and Pathology
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Electrospun Nanofibers in Biomedical Applications
- Research in Cotton Cultivation
- Crop Yield and Soil Fertility
- Hemoglobinopathies and Related Disorders
- Nanoparticle-Based Drug Delivery
- Plant and Fungal Interactions Research
- Wound Healing and Treatments
- Plant Disease Resistance and Genetics
- Genetic and phenotypic traits in livestock
- Hydrogels: synthesis, properties, applications
- Silk-based biomaterials and applications
- Iron Metabolism and Disorders
- Yeasts and Rust Fungi Studies
- RNA Interference and Gene Delivery
- Metal complexes synthesis and properties
- Extracellular vesicles in disease
- Agroforestry and silvopastoral systems
- Pneumocystis jirovecii pneumonia detection and treatment
- Livestock and Poultry Management
- Surgical Sutures and Adhesives
- X-ray Diffraction in Crystallography
- Magnetism in coordination complexes
North Carolina State University
2013-2024
Patanjali Research Foundation
2024
Shobhit University
2024
Jawaharlal Nehru Krishi Vishwa Vidyalaya
2024
Chhattisgarh Kamdhenu Vishwavidyalaya
2024
GD Goenka University
2017-2023
Homi Bhabha National Institute
2021
Tata Memorial Hospital
2021
Advanced Centre for Treatment, Research and Education in Cancer
2021
Indian Institute of Science Bangalore
2001-2020
The optimization of training populations and the use diagnostic markers as fixed effects increase predictive ability genomic prediction models in a cooperative wheat breeding panel. Plant programs often have access to large amount historical data that is highly unbalanced, particularly across years. This study examined approaches utilize these sets integrate selection into existing pipelines. We used cross-validation evaluate an unbalanced set 467 winter (Triticum aestivum L.) genotypes...
Grain yield is a trait of paramount importance in the breeding all cereals. In wheat (Triticum aestivum L.), has steadily increased since Green Revolution, though current rate increase not forecasted to keep pace with demand due growing world population and increasing affluence. While several genome-wide association studies (GWAS) on related component traits have been performed wheat, previous lack reference genome made comparisons between difficult. this study, GWAS for yield-related was...
Mycobacterium tuberculosis (Mtb) has evolved protective and detoxification mechanisms to maintain cytoplasmic redox balance in response exogenous oxidative stress encountered inside host phagocytes. In contrast, little is known about the dynamic of this pathogen endogenous generated within Mtb. Using a noninvasive specific biosensor state Mtb, we for first time discovered surprisingly high sensitivity perturbation homeostasis induced by elevated reactive oxygen species (ROS). We synthesized...
The majority of studies evaluating genomic selection (GS) for plant breeding have used single‐trait, single‐site models that ignore genotype × environment interaction (GEI) effects. However, such do not accurately reflect the complexities many applied programs, and previous papers found incorporate GEI effects multiple traits can increase accuracy estimated values (GEBVs). This study's goal was to test GS methods prediction in scenarios simulate early‐generation yield testing by correcting...
Awns are stiff, hair-like structures which grow from the lemmas of wheat (Triticum aestivum) and other grasses that contribute to photosynthesis play a role in seed dispersal. Variation awn length domesticated is controlled primarily by three major genes, most commonly dominant suppressor Tipped1 (B1). This study identifies transcription repressor responsible for inhibition at B1 locus. Association mapping was combined with analysis biparental populations delimit distal region 5AL...
Tuberculosis remains a major global health challenge worldwide, causing more than million deaths annually. To determine newer methods for detecting and combating the disease, it is necessary to characterise host responses infection. Several high throughput omics studies have provided rich resource including list of several genes differentially regulated in tuberculosis. An integrated analysis these identify unified response Such data integration met with challenges owing platform dependency,...
Abstract Stem rust was one of the most devastating diseases barley in North America. Through deployment cultivars with resistance gene Rpg1, losses to stem have been minimal over past 70 yr. However, there exist both domestic (QCCJB) and foreign (TTKSK aka isolate Ug99) pathotypes virulence for this important gene. To identify new sources barley, we evaluated Wild Barley Diversity Collection (WBDC) (314 ecogeographically diverse accessions Hordeum vulgare subsp. spontaneum) seedling four...
Germplasm collections hold valuable allelic diversity for crop improvement and genetic mapping of complex traits. To gain access to the within USDA National Small Grain Collection (NSGC), we developed Barley Recombinant Inbred Diverse Population (BRIDG6), a six-row spring barley multiparent population (MPP) with 88 cultivated accessions crossed common parent (Rasmusson). The parents were randomly selected from core subset NSGC that represents landrace breeding accessions. In total, generated 6160 F
Globally, individuals coinfected with the AIDS virus (HIV-1) and M. tuberculosis (causative agent of [TB]) pose major obstacles in clinical management both diseases. At heart this issue is apparent synergy between two human pathogens. On one hand, mechanisms induced by HIV-1 for reactivation TB patients are well characterized. other while findings clearly identified as a risk factor associated mortality, basic which exacerbates replication infection remain poorly The significance our...
The objective of present work is to fabricate porous three-dimensional biocomposite scaffolds with interconnected pore networks and mechanical strength for wound healing. Variable concentrations chitosan methylcellulose hydrogels were blended in the presence calcium cations prepare by freeze-drying method. Curcumin-aerosol was deposited over scaffold surface improve antimicrobial efficacy. Scaffold stability curcumin interaction evaluated Differential Scanning Calorimeter, Thermal...
AbstractThe antibacterial activities of two previously reported copper (II) coordination complexes [Cu(HL1)Cl2] and [Cu(HL2)Cl2], the new [Cu(HL3)Cl2] [Cu(HL4)Cl2], where HL1 is 2-(((pyridin-2-ylmethyl)amino)methyl)phenol, HL2 2-((benzyl(pyridine-2-ylmethyl)amino)methyl)phenol, HL3 2-(((pyridin-2-ylethyl)amino)methyl)phenol HL4 2-(((pyridin-2-ylmethyl)(quinolin-2-ylmethyl)-amino)methyl)phenol were investigated using agar well plate diffusion assay. The ligands characterized elemental...
Background: Antepartum haemorrhage (APH) is defined as bleeding from or into the genital tract after period of viability until delivery fetus. Etiology includes placenta previa, abruptio placentae, local causes, systemic causes and idiopathic origin. Objective this study was to identify factors associated with APH, quantitate maternal morbidity, mortality perinatal outcome in patients APH at a tertiary care center India. Methods: The retrospective observational patient information obtained...
Using protonated forms of tridentate phenol amine ligand 2-((benzyl(pyridine-2-ylmethyl)amino)methyl)phenol (HL) mononuclear copper(II) complex was synthesized. This yielded composition [Cu(HL)Cl2] (1) which has been characterized by X-ray crystallography, UV–vis, and EPR measurements. Complex 1 shows axial spectra typical d9 (dx2-y2 as ground state) configuration. DFT/B3LYP/LANL2DZ 6-311++G(d,p) level theory, structural optimization, electronic vibrational characteristics the were examined....
Objective: To develop a chitosan-based scaffold and carry out complete comprehensive study encompassing optimization of exact chitosan strength, product characterization, toxicity evaluation, in vitro validation cell culture experiments, finally vivo efficacy animal excision wound model. Materials Methods: Developed scaffolds (CSs) were optimized for tissue engineering healing by means microstructure, toxicity, biocompatibility evaluation. Results: Scanning electron microscope (SEM) studies...
Although kernel weight (KW) is a major component of grain yield, its contribution to yield genetic gain during breeding history has been minimal. This highlights an untapped potential for further increases in via improving KW. We investigated variation and genetics KW length (KL) genome-wide association studies (GWAS) using historical contemporary soft red winter wheat population representing 200 years selection the United States. The observed changes KL over time did not show any conclusive...
Abstract Poly(HEMA‐MAA) hydrogel particles were synthesized by redox free‐radical polymerization using 2‐hydroxyethylmethacrylate, different concentration of methacrylic acid as monomer, ethyleneglycol dimethacrylate crosslinking agent, and APS/TEMED initiator. Fourier transform infrared spectrum poly(HEMA‐MAA) hydrogels showed intense absorption peak carbonyl group at ∼ 1700 cm −1 due to carboxylic groups MAA, 2960 CH stretching vinylic independent MAA concentration. Highest swelling...