A5068119853- Genital Health and Disease
- Urological Disorders and Treatments
- Sexual function and dysfunction studies
- Prostate Cancer Treatment and Research
- Pancreatitis Pathology and Treatment
- Prostate Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Surgical Simulation and Training
- Diversity and Career in Medicine
- Urinary Bladder and Prostate Research
- Colorectal Cancer Surgical Treatments
- Hormonal and reproductive studies
- Pancreatic and Hepatic Oncology Research
- Trauma Management and Diagnosis
- Sexual Differentiation and Disorders
- Testicular diseases and treatments
- Liver Disease Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Radiopharmaceutical Chemistry and Applications
- Abdominal Trauma and Injuries
- Bladder and Urothelial Cancer Treatments
- Stroke Rehabilitation and Recovery
- Stoma care and complications
- Surgical site infection prevention
Woodlands Health Campus
2025
Nottingham University Hospitals NHS Trust
2020-2022
Western Health
2020
The Alfred Hospital
2020
Florey Institute of Neuroscience and Mental Health
2016-2020
Eastern Health
2016-2020
Monash Health
2016-2020
Monash University
2016-2020
The University of Melbourne
2020
Austin Health
2020
Earlier studies have demonstrated an unexplained depletion of the epidermal growth factor receptor (EGFR) protein expression in prostatic cancer. We now attribute this phenomenon to presence a variant EGFR (EGFRvIII) that is highly expressed malignant neoplasms. In retrospective study, normal, benign hyperplastic and tissues were examined at mRNA levels for mutant receptor. The results whilst EGFRvIII was not present normal glands, level increased progressively with gradual transformation...
We examined the effects of an aerobic exercise intervention on adiposity outcomes that may be involved in association between physical activity and breast cancer risk. This study was a two-centre, two-armed, randomized controlled trial. The 1-year-long included 45 min moderate-to-vigorous five times per week, with at least three sessions being facility based. control group asked not to change their both groups were diet. A total 320 postmenopausal, sedentary, normal weight-to-obese women...
Lower limb compartment syndrome after prolonged surgical procedures performed in the lithotomy position is a rare but potentially devastating complication. It recognised urological, colorectal, and gynaecological procedures. Sixteen cases of urological surgery have been reported. The objective this study was to estimate incidence complication practice identify risk factors for its development.A postal survey UK consultant urologists conducted.Replies were received from 261 consultants. In...
Evidence is presented for a non-specific ulcerative process in the small bowel of patients with rheumatoid arthritis. All three cases lower gastrointestinal bleeding; on withdrawal non-steroidal anti-inflammatory drugs no further bleeding occurred. Non-steroidal may lead to ulceration inhibiting mucosal glycoprotein synthesis and increasing intestinal permeability.
Simulation is now firmly established in modern surgical training and applicable not only to acquiring skills but also non-surgical professionalism. A 5-day intensive Urology Boot Camp was run teach emergency procedural skills, clinical reasoning, communication using scenario simulations, endoscopic laparoscopic trainers. This paper reports the educational value of this first urology boot camp. Sixteen UK trainees completed pre-course questionnaires on their operative experience confidence...
Patients with gender dysphoria (GD) suffer from a constant feeling of psychological discomfort related to their anatomical sex. Gender reassignment surgery (GRS) attempts release this discomfort. The aim study was compare the functioning cohort or patients GD before and after GRS. We hypothesised that there would be an improvement in scores self-administered SCL-90R following among male-to-female people dysphoria. studied 40 DSM-IV diagnosis Identity Disorder (GID) who attended Leicester...
The COVID-19 pandemic has changed training and recruitment in urology unprecedented ways. As efforts are made to ensure trainees can continue progress, lessons be learned improve urological practice even after the acute phase of is over. Novel methods education through virtual learning have burgeoned amidst social distancing brought. importance human factors non-technical skills also been brought fore while operating under constraints personal protective equipment working new teams...
Abstract BACKGROUND CaP has a higher incidence and mortality in Black men. We hypothesized that subpopulation differences AR expression may contribute to this phenomenon. METHOD immunostaining was compared epithelium PES of normal, BPH, tissues from African men UK Caucasian RESULTS similar normal prostatic both groups, but BPH than ( P ≤ 0.0001). Also, normal/atrophic benign hyperplastic tissues, there significant loss groups (normal stroma versus CONCLUSIONS Variations between...
Storage of unstained paraffin slides may lead to the deterioration specimens and failure detect cellular proteins immunohistochemically. Although implication age-induced alterations on multicenter immunohistochemical studies would be considerable, they have not been investigated previously. The current study was undertaken examine effect this factor further explore new ways overcoming resultant shortcomings. authors now report immunodetection a host antigens in similarly preserved serial...
Certain testicular tumours may present with gynaecomastia 1–3 . Rarely in these cases is the tumour not palpable at initial clinical examination or follow-up examinations. To enable early detection of occult a serum hormonal profile followed by high resolution ultrasound testes are necessary 3–7 We report case Leydig cell which antedated presence swelling 7 months.
The management of erectile dysfunction looks set to be revolutionised with the introduction effective oral therapies. There will remain, however, some men who do not respond conservative measures. This article reviews important role penile prosthetic surgery as a treatment option in these patients.
Many components make up a successful comprehensive gender realignment service. These vary throughout the different UK-based services. We argue that it is essential to incorporate views of patients using such services ensure these meet expectations and needs as well eliminate post-operative regret where possible. Early age for surgery in accurately diagnosed with meaningful support, equality access reducing complications were all considered be important factors by our patients. Incorporating...
We have reviewed articles published on penile prosthetic infection in Medline and EMBASE databases from 2000 to 2012 with the intention of signposting ‘best evidence’ for UK implanter. Using Oxford Centre Evidence-based Medicine Levels Evidence (LE), no paper exceeded an LE 2b majority were 4 (case series) 5 (expert opinion). This is not surprising a perspective since HES data 2009 2010 reported 263 surgeries performed 35 hospitals, only five hospitals performing 15 or more. Our literature...
Two consecutive randomized trials following injection sclerotherapy for varicose veins compared 3 and 6 weeks bandaging in 148 patients 1 to 130 patients. Objective assessment patient's symptoms, using a scoring system, correlated well showed that there was no difference whatsoever between weeks' after year follow-up. In the second trial, who were bandaged significantly better (P < 0.001) than only one week of at maximum follow up 4 years. Long term primary suggests is superior bandaging,...
A Cowper's syringocele in an adult is rare. Ten cases are reported the world literature. The authors report a case of painful haematuria due to presence adult. classification lesions gland discussed together with common symptoms and differential diagnosis.
Abstract Controlled intraduct infusion and peri-acinar dispersal of 100 µl buffer containing sodium glycodeoxycholate (GDOC) at concentrations 8·5, 17 34 mmol/l in rats caused a progressively severe acute pancreatitis from which none the animals died over experimental period. Infusion affinity-purified active human enterokinase did not cause pancreatitis, presumably because inability macromolecule to gain access its specific intracellular substrate trypsinogens. The addition 200 ng GDOC...