A5100657230- Supramolecular Chemistry and Complexes
- Supramolecular Self-Assembly in Materials
- Luminescence and Fluorescent Materials
- Dendrimers and Hyperbranched Polymers
- Advanced Polymer Synthesis and Characterization
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Liver Diseases and Immunity
- Systemic Lupus Erythematosus Research
- Metal-Organic Frameworks: Synthesis and Applications
- High-pressure geophysics and materials
- Immune Response and Inflammation
- Immunodeficiency and Autoimmune Disorders
- Nuclear physics research studies
- Dietary Effects on Health
- Autophagy in Disease and Therapy
- Legionella and Acanthamoeba research
- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Advanced Chemical Physics Studies
- Chemical Synthesis and Analysis
- Parasitic Infections and Diagnostics
- Clostridium difficile and Clostridium perfringens research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Antifungal resistance and susceptibility
The University of Sydney
2024
Northwestern Polytechnical University
2015-2020
China XD Group (China)
2015-2016
University of Birmingham
2010
Despite the widespread clinical application of chemotherapeutic anticancer drugs, their adverse side effects and inefficient performances remain ongoing issues. A drug delivery system (DDS) designed for a specific cancer may therefore overcome drawbacks single drugs provide precise synergistical treatment by introducing exclusive stimulus responsiveness combined chemotherapy properties. Herein, we report design synthesis supramolecular assembly 1 constructed orthogonal self-assembly...
PGMA-based supramolecular hyperbranched polycations were synthesized for effective gene delivery.
Abstract Despite the remarkable progress made in controllable self‐assembly of stimuli‐responsive supramolecular polymers (SSPs), a basic issue that has not been consideration to date is essential binding site. The noncovalent sites, which connect building blocks and endow with their ability respond stimuli, are expected strongly affect SSPs. Herein, design synthesis dual‐stimuli thermo‐ photoresponsive Y‐shaped polymer (SSP2) two adjacent β‐cyclodextrin/azobenzene (β‐CD/Azo) another SSP...
A novel “D<sub>3</sub>–AC–E<sub>3</sub>” triple-monomer methodology was proposed to construct supramolecular hyperbranched alternating polymers.
A novel supramolecular alternating polymer is constructed based on double molecular recognition events of benzo-21-crown-7 with a secondary ammonium salt and pillar[5]arene neutral guest. The resulting utilized to prepare hierarchical materials different dimensionalities for the first time. These included zero-dimensional spherical aggregates, one-dimensional nanofibers, two-dimensional microstructured films, three-dimensional ordered glue. This development will be helpful designing...
Importance: Although prolonged fasting has become increasingly popular, the favourable biological adaptations and possible adverse effects in humans have yet to be fully elucidated. Objective: To investigate of a three-day water-only fasting, with or without exercise-induced glycogen depletion, on autophagy activation molecular pathways involved cellular damage accumulation repair healthy humans. Design: A randomised, single-centre, two-period, two-sequence crossover trial. The primary...
The main goal of this paper is to investigate the properties low-energy quadrupole strength in Ni isotopes, especially for evolution pygmy states with increasing neutron number. And effect shell on resonance also discussed detail. Skyrme Hartree-Fock+Bardeen-Cooper-Schrieffer (HF+BCS) theory and selfconsistent quasiparticle random phase approximation (RPA) method are employed top three effective interactions named SGII, SLy5 SKM<sup>*</sup>. In calculations, a density-dependent...
The reversible self-assembly behavior of thermoresponsive γ-shaped polymer can be effectively tuned based on the inclusion complexation, intermolecular hydrogen bonding and steric hindrance β-CD.
Chem-KVL is a tandem repeating peptide that was modified based on short from fragment of the human host defense protein chemerin. has 14 amino acids and shows broad-spectrum antibacterial activity, it increases cationicity hydrophobicity. To determine whether staple-modified would improve activity protease stability, we designed series stapled peptides tested against several gram-positive gram-negative bacteria, including Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli. We...
Background: Anti-CD20 (rituximab) therapy has been very successful in SLE patients resistant to conventional therapy, with about 80% of responding most open label case series. However, 30% develop anti-drug antibodies (ADA), which may have a detrimental effect on the efficacy drug. Identifying ADA is, therefore, important predict non-responders and explain loss efficacy, but low levels be missed because formation immune complexes A novel approach this problem is acid disruption immediately...