Joris Hautekiet

ORCID: 0000-0001-9624-0428
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Colorectal and Anal Carcinomas
  • Adrenal Hormones and Disorders
  • Cervical Cancer and HPV Research
  • Drug-Induced Ocular Toxicity
  • SARS-CoV-2 and COVID-19 Research
  • Platelet Disorders and Treatments
  • Long-Term Effects of COVID-19
  • Complement system in diseases
  • SARS-CoV-2 detection and testing
  • Pancreatic and Hepatic Oncology Research
  • Immune responses and vaccinations
  • Esophageal Cancer Research and Treatment
  • Sepsis Diagnosis and Treatment
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Renal Diseases and Glomerulopathies
  • Genetic factors in colorectal cancer
  • Diagnosis and treatment of tuberculosis
  • Clinical Reasoning and Diagnostic Skills

Sciensano (Belgium)
2020-2022

Ghent University
2020-2022

Objective Sotrovimab, a dual-action, engineered human monoclonal antibody, has been demonstrated to significantly reduce the risk of hospitalisation and death in high-risk patients with COVID-19. Here, we describe real-world use of, outcomes from, sotrovimab treatment Belgium during Delta Omicron waves among COVID-19 at high developing severe disease.

10.1080/17843286.2024.2381272 article EN Acta Clinica Belgica 2024-05-03

Topic: 32. Platelet disorders Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare, life-threatening disorder, caused by autoantibody-mediated deficiency of disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13). Real-world data from Germany, France, the United Kingdom confirm that caplacizumab allows rapid recovery iTTP. Caplacizumab has been commercialized reimbursed in Belgium since September 1, 2019. on treatment iTTP patients...

10.1097/01.hs9.0000973308.93798.cb article EN cc-by-nc-nd HemaSphere 2023-08-01

Abstract Background Sotrovimab, a dual-action, engineered human monoclonal antibody, has been demonstrated to significantly reduce the risk of hospitalization and death in high-risk patients with COVID-19. Here, we describe real-world use of, outcomes from, sotrovimab treatment Belgium during Delta Omicron waves among COVID-19 at high developing severe disease. Methods This was multicentric, single-arm observational cohort study non-hospitalized receiving outpatient between 1 November 2021 2...

10.1101/2023.12.14.23298578 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2023-12-18

Meta-analyses of survival studies aim to reveal the variation an effect measure interest over different and present a meaningful summary. They must address between study heterogeneity in several dimensions eliminate spurious sources variation. Forest plots usual (adjusted) hazard ratios are fraught with difficulties from this perspective since both magnitude interpretation these depend on factors ancillary true study-specific exposure effect. These generally include duration, censoring...

10.48550/arxiv.2111.13132 preprint EN other-oa arXiv (Cornell University) 2021-01-01
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