Introduction: Bone mass density (BMD) is still the gold standard for diagnosis of osteoporosis, but bone turnover markers (BTMs) can provide helpful information regarding remodeling process. The aim this study was to determine correlations between BMD and serum levels BTMs (tartrate-resistant acid phosphatase-5b [TRAP-5b]), bone-specific alkaline phosphatase (BSAP), estradiol (E 2 ), magnesium (Mg [2+] ) ion concentrations in postmenopausal osteoporotic women as compared healthy subjects....

Background PAPP is widely used in Australia as a potent vertebrate bait, with potential for off‐target ingestion and poisoning domestic dogs. Whilst toxicosis resulting methaemoglobinaemia anecdotally known to occur, this the first description literature. This study reports thirteen clinical cases of suspected Para‐aminopropiophenone (PAPP) toxicity dogs, aim describing presentation current management species. Case report Three veterinary clinics Victoria provided records dogs where was...

Objectives: This study aimed to evaluate patients’ satisfaction with the esthetic outcomes of combined endodontic and prosthetic treatments for devitalized or dyschromic teeth, a condition influenced by various intrinsic extrinsic factors that present growing concern in modern dentistry. Methods: A total 104 patients, including 43 men 61 women, underwent treatment using lithium disilicate restorations zones zirconium oxide regions higher occlusal demands. Patient was evaluated through...

Background and Objectives: This five-year retrospective study evaluated the survival clinical performance of 1143 zirconium oxide restorations, including both monolithic (144) layered (999) restorations. Materials Methods: The analysis included records follow-up data patients treated with Failures in restorations were examined, particularly focusing on chipping caused by unsupported feldspathic ceramic exceeding 1.5 mm. Monolithic used as a benchmark for durability. Results: results...

One of the most frequent forms maternal morbidity following childbirth is postpartum depression. Postpartum depression (PPD), a disabling condition as major public health concern, has significant negative impact on child's emotional, mental well intellectual development if left undiagnosed and untreated, which can later have long-term complications. The oxytocin system an excellent candidate gene in context. Differences vulnerability mothers for onset psychiatric disorders could be...

Background and Objectives: The main objectives of our study were to assess sexual dimorphism compare the facial height, as well anteroposterior width upper airway, within adult Caucasians diagnosed with skeletal Class I III malocclusion, based on a number angular linear cephalometric parameters. Materials Methods: One hundred lateral cephalograms selected from orthodontic Caucasian patients western Romania. Several parameters (SNA, SNB, ANB, FMA, Y–FH, Ba–S–PNS NL–ML angles) (total, lower...

Background and Objectives: Medication-related osteonecrosis of the jaw (MRONJ) was first recognized as a disease entity reported in literature 2003. Within few years, incidence MRONJ has increased significantly, to point where now it can be seen every dental clinic around world. Its prevention management still remain major challenges for dentists oral maxillofacial surgeons. Materials Methods: This prospective clinical study conducted at Oral Maxillofacial Surgery Clinic Timisoara 6-month...

BACKGROUND Periodontal disease, a frequent oral health problem, is connected with cardiovascular morbidity and mortality. This study aimed to assess the unstimulated saliva flow rate pH as markers of severity periodontal disease in patients disease. MATERIAL AND METHODS A cohort 155 (78 men 77 women, aged 30-92 years) was included, structured questionnaire obtained information about their status, healthcare behaviors, eating habits. An examination performed status presence dental calculus....

The purpose of this study was to evaluate the clinical outcome feldspathic ceramic laminate veneers over a 7-year period using minimally invasive techniques, such as vertical preparation (without prosthetic finish line), or no (no-prep). A total 170 were cemented in anterior region, including 70 maxillary and 100 mandibular veneers, after special conditioning teeth restorations. evaluated FDI World Dental Federation criteria evaluation kit recalling all patients between February June 2021....

Persistent infections with high risk human papillomaviruses (HR-HPV) cause virtually all cervical cancers. An observational study was conducted aiming to estimate the rate of HPV infection persistence after LEEP in patients grade squamous intraepithelial lesions (HSIL). Moreover, investigated if is age related. For this reason a total 110 were included between January 2010 and June 2015. At 6 months overall 40.9 %, at 12 20 % 18 11.8 %. Type 16 showed highest rate: 27.3 months, 12.7 10 LEEP....

Study design: Mechanical thrombectomy (MT) via the transbrachial approach (TBA) is a very rare option used in cases of patients with aortic pathologies and acute ischemic stroke (AIS) due to insufficient evidence literature, difficulty from technical point view result this technique influenced by complications that frequently accompany it. Background: Only few where MT TBA were reported its application emergency management AIS has still not been dealt detail. Objectives: Out need clarify...

Background and objectives: To minimize stroke-related deaths maximize the likelihood of cerebral reperfusion, medical professionals developed “code stroke” emergency protocol, which allows for prompt evaluation patients with acute ischemic stroke symptoms in pre-hospital care department (ED). This research will outline our experience implementing code protocol its impact on door-to-needle time (DTN) ED. Methods: Our study included a alert” upon arrival at department. The final sample this...

Dental development is relatively independent from other systems maturation. Recent studies have reported changes in the timing of tooth for contemporary children comparing to that lived more than 30 years ago (secular trend). Detectable variations tempo mineralization and duration maturation between different geographical regions were reported. age important not only dental specialists, but also pediatricians (in evaluation growth healthy children, pediatric endocrinology, with diseases or...

Cardioembolic stroke (CES), generally known as the most severe subtype of ischemic stroke, is related to many factors, including diabetes mellitus (DM), hypertension (HTN), smoking, hyperlipidemia and atrial fibrillation (AF). Genetic mutations methylenetetrahydrofolate reductase (MTHFR) gene C677T A1298C have been recently associated with stroke. The purpose this study was analyze prevalence MTHFR polymorphisms correlated cardiovascular risk factors in a selected population patients CES due...

Background and Objectives: Ceramic veneers represent the most appropriate treatment option for minimally invasive aesthetic rehabilitation. For long-term clinical success, accurate marginal internal adaptation of dental restorations are paramount importance. The aim this in vitro study is to assess effect a novel (patented) design compared conventional ones on their gap prepared tooth surface. Materials Methods: Twenty-four lithium disilicate ceramic obtained using Computer-Aided-Design...

Background and Objectives: In Coronavirus Disease 2019 (COVID-19), which is caused by the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), clinical manifestations are primarily related to pulmonary system. Under 10% of cases also develop gastrointestinal events such as diarrhea, nausea, vomiting abdominal pain. Materials Methods: We conducted an observational, retrospective study in Infectious Diseases Clinic “Victor Babes” Hospital, Timis County, order assess...

Background and Objectives: Non-invasive prenatal testing (NIPT) has been confirmed as the most accurate screening test for trisomies 21, 18, 13, sex chromosomes aneuploidies several microdeletions. This study aimed to assess accuracy of cell free DNA based on low-level whole-genome sequencing screen these chromosomal abnormalities evaluate clinical performance NIPT. Materials Methods: 380 consecutive cases from a single genetic center, Western Romania were included in this retrospective...

Although the intravenous tissue plasminogen activator (rt-PA) has been shown to be effective in treatment of acute ischemic stroke (AIS), only a small proportion patients receive this drug. The low administration rate is mainly due delayed presentation emergency department (ED) or lack team/unit most hospitals. Thus, aim study analyze ED time targets and rt-PA after initial admission with AIS an from traditional healthcare center (without neurologist team/unit).

The impression materials utilized today in dental medicine offer a good reproducibility and are easily accepted by patients. However, because they polymer-based, have issues regarding their dimensional stability. In this respect, the present work proposes new type of impression, which is reinforced with rigid mouthguards. aim study to test performances such impressions comparing them conventional ones—from critical point view, Three types polymeric were considered for both impressions:...

We aimed to validate PDGF-BB protein expression by RNAscope, a sensitive method for mRNA evaluation on paraffin embedded (FFPE) specimens of ovarian tumors.Seventy-five FFPE cancer biopsies were assessed immunohistochemistry followed RNAscope validation.Dual in tumor and stromal cells have been observed, being highly suggestive mediated stromal-tumor reciprocal interaction (p=0.008). It seems that the nuclear represents negative prognostic factor tumors. Being controversial issue literature,...

Depression and anxiety are prevalent issues amongst individuals suffering from thoracic cancer. Gender differences in coping with cancer have a serious impact upon the management of emotional distress. The purpose our study has been to assess sex variations handling depression, including use mechanisms their relationship respect depression.This cross-sectional registered 18 women 22 men non-metastatic lung operated upon. Pre-operatively at one month post-operatively, patients were assessed...

Background and objectives: The purpose of the study is to correlate vascular calcification biomarkers osteoprotegerin (OPG) 25-hydroxyvitamin D3 (25-OH-D3), indicators arterial stiffness carotid-femoral pulse wave velocity (c-f PWV) renal resistive index (RRI), with parameters left ventricular function in heart failure patients versus control. Materials methods: Our case-control compared 60 ischemic reduced ejection fraction (LVEF) (<40%) a control group healthy age-matched subjects (CON)....