- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Spondyloarthritis Studies and Treatments
- Adolescent and Pediatric Healthcare
- Diabetes and associated disorders
- Inflammatory Bowel Disease
- Diabetes Management and Research
Sechenov University
2023-2025
Psoriatic arthritis is a chronic inflammatory disease of the peripheral joints, spinal joints and entheses, occurring in 10–25% patients with psoriasis. Juvenile psoriatic classified as subtype juvenile idiopathic arthritis. Treatment challenging. One main difficulties that drugs used adult have restrictions for use pediatric practice, which limits available therapeutic options. There are few studies assessing effectiveness safety secakinumab therapy practice. Objective . To evaluate...
Inflammatory bowel diseases (IBD) Crohn's disease (CD) and ulcerative colitis (UC) are a group of idiopathic abnormal conditions with unclear etiology similar clinical courses. In addition to intestinal syndrome, these often associated extraintestinal manifestations, the most common which is involvement peripheral joints axial skeleton. The increase in incidence IBD, especially CD, childhood warrants further study this condition's features, including manifestation: joint (JI) pediatric...
Systemic juvenile idiopathic arthritis (SJIA) accounts for 10–15% of cases. The incidence inflammatory bowel disease (IBD) is generally higher in SJIA patients than the general pediatric population; however, association IBD with rare. Among 65 managed two rheumatology centers, was detected 3 3, 8, and 10 years from onset. clinical presentation rather scanty; diagnosis mainly based on colonoscopy biopsy results. In 2 patients, Crohn's diagnosed, undifferentiated colitis 1 patient.
BACKGROUND: In coexistence of diabetes mellitus type 1 (DM1) with severe autoimmune and inflammatory diseases some patients need simultaneous administration insulin glucocorticoids (GC). GC therapy in DM1 can worsen glycemic control. AIM: To determine characteristics children adolescents receiving GC. DESCRIPTION OF CLINICAL CASES: We observed 5 for juvenile idiopathic arthritis (JIA), systemic sclerosis (JSS), dermatomyositis (JDM), ulcerative colitis (UC), reactive (RA). Intra-articular...