A5101857662- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Inflammatory mediators and NSAID effects
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Colorectal and Anal Carcinomas
- Diverse Approaches in Healthcare and Education Studies
- Colorectal Cancer Surgical Treatments
- Cancer Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Consumer Perception and Purchasing Behavior
- Gastrointestinal disorders and treatments
- Oral and gingival health research
- Chronic Myeloid Leukemia Treatments
- Hedgehog Signaling Pathway Studies
- Pancreatic and Hepatic Oncology Research
- Technology and Data Analysis
- Biliary and Gastrointestinal Fistulas
- Healthcare and Venom Research
- Cancer, Lipids, and Metabolism
- Diverse Topics in Contemporary Research
- Pediatric Hepatobiliary Diseases and Treatments
- Helicobacter pylori-related gastroenterology studies
- Phagocytosis and Immune Regulation
- Gallbladder and Bile Duct Disorders
Korea University
2018-2024
Hankuk University of Foreign Studies
2023
Inje University Busan Paik Hospital
2005-2023
Inje University
2014-2015
Proliferation marker Ki-67 is widely used in cancer prognosis prediction. We tried to investigate the role of as a prognostic factor stomach after surgery this study.We retrospectively evaluated 251 patients who underwent curative resection for gastric from 2010 2015. In pathologic examination, labeling index was defined percentage antigen positive cells. Prognostic significance evaluated. Disease-free survival (DFS) assessed primary end-point.The median follow-up period 28.0 months....
Imatinib is a powerful tyrosine kinase inhibitor that specifically targets BCR‑ABL, c‑KIT, and PDGFR kinases, used in the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors, other types cancers. However, possible anticancer effects imatinib gastric cancer have not yet been explored. The present study evaluated vitro on cells determined molecular mechanism underlying these effects. We induced mitochondria‑mediated apoptosis by involving endoplasmic reticulum (ER)...
Daunorubicin, also known as daunomycin, is a DNA‑targeting anticancer drug that used chemotherapy, mainly for patients with leukemia. It has been shown to have effects in monotherapy or combination therapy solid tumors, but at present it not adequately studied colorectal cancer (CRC). In the study, from screening using an FDA‑approved library, was found daunorubicin suppresses GLI‑dependent luciferase reporter activity. Daunorubicin increased p53 levels, which contributed both GLI1...
To maintain the patient's quality of life, surgeons strive to preserve sphincter during rectal cancer surgery. This study evaluated oncologic safety a sphincter-saving resection with distal margin (DRM) <1 cm without radiotherapy in T3, mid- or low-rectal cancer.This retrospective enrolled 327 patients who underwent for proven T3 located <10 from anal verge and between January 1995 December 2011. The outcomes included 5-year cancer-specific survival, local recurrence, systemic recurrence...
This case report presents an unusual of cholangiocarcinoma arising nearly 35 years after cystoduodenostomy for choledochal cyst. The patient visited our hospital with dyspepsia and studies revealed bezoar within the cyst caused by bile food reflux. underwent pancreaticoduodenectomy a biopsy adenocarcinoma, stage IIB. After 19 months, has no recurrence to date recovered well. shows that proper surgical management meticulous, long-term follow-up is imperative patients congenital
Doxifluridine (DF), an oral 5-FU prodrug, has been used for various solid cancers due to its efficacy and low toxicity. We aim evaluate the effect of DF as adjuvant monotherapy in advanced gastric cancer. retrospectively reviewed clinical data 263 patients with cancer who underwent curative gastrectomy between January 2010 December 2013 at our institute. Since previous randomized control trials have confirmed S-1 chemotherapy cancer, we analyzed oncologic patient compliance group compared...
Prostaglandin E2 (PGE2) is a contributory carcinogen in gastric adenocarcinoma. 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) catabolizes PGE2 by oxidizing its 15(s)-hydroxy group. The aim of this study was to investigate the expression 15-PGDH adenocarcinoma tissue and relationship between clinicopathologic features adenocarcinoma.Ninety-nine patients who underwent surgical resection for January 2007 December were enrolled evaluated retrospectively.In 62 (62.6%), lower than nonneoplastic...
Purpose Remnant gastric cancer is defined as a malignant tumor developing on the remnant side of stomach after partial gastrectomy. The purpose this study to evaluate clinical characteristics and prognosis according cause reconstruction method previous surgery. Methods Between January 2007 February 2016, we analyzed 39 patients with their medical records who were diagnosed underwent gastrectomy at Inje University Busan Paik Hospital. Results In comparison disease (MD) benign diseases (BD)...
Purpose: Extracapsular invasion (ECI) of nodal metastasis is reported to be a prognosticator colorectal cancer.However, limited knowledge exists about the prognostic value ECI in stage III rectal cancer.Methods: From January 1996 June 2004, 202 cancer patients who underwent surgery were enrolled this study.The divided into two groups according (patients with ECI, ECIP, n=122; without ECIN, n=80).The potential factors compared Cox model.Results: Of 916 positive nodes examined, was seen 46.7%...
Purpose: Endoscopic ultrasonography (EUS) is a useful imaging procedure for the diagnosis of submucosal tumors in stomach. The present study investigated EUS features benign and malignant gastrointestinal stromal tumors(GISTs) assessed differences between two groups. Materials Methods: Thirty patients with GIST stomach were included (23 7 GISTs). We compared characteristic findings (tumor size, location tumor, regularity outer margin, echoheterogeneity, presence cystic spaces, echogenic foci...