A5101942928- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Multiple Sclerosis Research Studies
- Epilepsy research and treatment
- Sympathectomy and Hyperhidrosis Treatments
- Biochemical effects in animals
- Peripheral Neuropathies and Disorders
- Healthcare and Venom Research
- Ophthalmology and Eye Disorders
- Myasthenia Gravis and Thymoma
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neurological Disorders and Treatments
- Orthopedic Surgery and Rehabilitation
- IgG4-Related and Inflammatory Diseases
- Psychosomatic Disorders and Their Treatments
- Pharmacological Effects and Toxicity Studies
- Genetics and Neurodevelopmental Disorders
- Glycogen Storage Diseases and Myoclonus
- Autoimmune Neurological Disorders and Treatments
- Vestibular and auditory disorders
- Lymphadenopathy Diagnosis and Analysis
- Gout, Hyperuricemia, Uric Acid
- Cardiovascular Disease and Adiposity
- Cancer Treatment and Pharmacology
- Leprosy Research and Treatment
Heinrich Heine University Düsseldorf
2025
Düsseldorf University Hospital
2025
Sağlık Bilimleri Üniversitesi
2020-2024
Bakırköy Psychiatric Hospital
2013-2024
Dokuz Eylül University
1998-2024
Hacettepe University
2024
University of Health Sciences
2022
University of Health Science
2022
İstanbul Eğitim ve Araştırma Hastanesi
2020
Türkisch-Deutsche Universität
2020
Background and aims Migraine headache is one of the most common primary disorders three times more prevalent in women than men, especially during reproductive ages. The neurobiological basis female dominance has been partly established. present study aimed to investigate effect gender on manifestations migraine patients. Methods group consisted 2082 adult patients from five different hospitals’ tertiary care-based clinics. relationship between characteristics was evaluated with aura (MwA)...
Objectives.—The aim of this study is to assess the comprehensibility, internal consistency, patient‐physician reliability, test‐retest and validity Turkish version Migraine Disability Assessment (MIDAS) questionnaire in patients with headache. Background.—MIDAS has been developed by Stewart et al shown be reliable valid determine degree disability caused migraine. Design Methods .—This was designed as a national multicenter demonstrate reliability MIDAS questionnaire. Patients applying 17...
The relation of epilepsy with psychiatric disorders is great interest to researchers due its behavioral, social, and cognitive outcomes. In this study, we explored comorbidity effects on quality life (QOL) in patients mesial temporal lobe (MTLE) juvenile myoclonic (JME).Thirty MTLE, 30 JME, healthy controls underwent the Structured Clinical Interview for DSM-IV (SCID-I) diagnose disorders. None subjects had previously undergone examination. Quality Life Epilepsy Inventory-89 (QOLIE-89) was...
Einleitung: Neue Strategien zur Behandlung der Myasthenia gravis (MG) umfassen die Inhibition des Komplementfaktors C5 (C5IT) sowie den Antagonismus neonatalen Fc-Rezeptors (FcRn) und stellen vielversprechende Optionen für hochaktive Verläufe dar. Bisher verfügbare indirekte Vergleiche dieser Therapiemechanismen ergaben heterogene Resultate. Ziel Studie ist daher ein direkter Vergleich in einem Real World-Setting.
Abstract Objectives This study aimed to compare blood choline levels and its correlations with bone mineral density (BMD) calcium, vitamin D, parathyroid hormone (PTH) in patients osteoporosis healthy controls. Background Osteoporosis is a condition marked by reduced higher risk of fractures, posing major health concern. Cholinergic activity promotes formation, while inhibition may contribute loss. Methods Blood 64 female participants, 38 26 were measured using ELISA, BMD was assessed via...
Migraine is more likely to be misdiagnosed in patients with comorbid diseases. Not only primary care physicians, but also specialists might misdiagnose it due the lack of diagnostic criteria awareness. The ID migraine test a reliable screening instrument that may facilitate and accelerate recognition. This study aimed compare prevalence characteristics large sample admitted clinics ophthalmology (OC), ear, nose throat diseases (ENTC) neurology (NC), as well validate use OC ENTC settings. was...
<i>Aim:</i> To determine the frequency of epilepsies in family members epileptic patients. <i>Methods:</i> The records 4,851 patients with epilepsy were reviewed. and patterns different syndromes patients, number affected relatives consanguinity studied. <i>Results: </i>A total 1,753 excluded due to various reasons. Of remaining 296 (9.5% 3,098) had first- or second-degree seizures. incidence history localization-related cryptogenic group was significantly...
Aim Chronic migraine is a growing and disabling subtype of with different risk factors clinical features, even in older adults. We sought to define differentiate features chronic also aimed compare major adults those younger people both sexes. Methods used electronic dataset ( T urkish Headache Database) from 13 tertiary headache centers urkey. Electronic included detailed headache‐defining according ICHD‐II criteria based on face‐to‐face interviews examination by specialist. Using...
Abstract Aim: We aimed to determine the efficacy and safety of etodolac, in acute migraine attacks comparison with paracetamol (acetaminophen). Methods: designed a randomized, double‐blind, crossover phase III clinical trial for patients diagnosed at least 1 year, according ICHD‐II criteria. Two hundred twenty‐nine adult having 2 8 monthly from 17 centers were included. The instructed use 3 attack treatment packages consisting 1,000 mg paracetamol, 400 800 etodolac on moderate–severe...
Objective To investigate which part of the autonomic system is mainly involved and assess sensitivity face sympathetic skin response in cluster headache. Material methods The study sample consisted 19 drug-free headache patients (16 males, three females) healthy volunteers. Demographic features pain characteristics were thoroughly identified. Dysautonomic symptoms evaluated during attack remission periods patients. Orthostatic hypotension, R-R interval variation responses obtained from four...
Serum uric acid (SUA), the end product of purine metabolism acts as an antioxidant and is related to oxidative stress. It has been reported that SUA may be involved in pathogenesis neurodegenerative diseases including Alzheimer disease, Huntington Parkinson multiple sclerosis. However, studies evaluating levels migraine are scarce. This study aimed explore relationship between pain characteristics patients with compare during a headache attack headache-free period those control groups....
Matrix metalloproteinases (MMP) are the enzymes responsible for proteolytic ac-tivity of extracellular matrix proteins. Tissue inhibitors (TIMPs) their endogenous inhibitors. MMP-9 acts on basal membrane cerebellar epithe-lium and is antagonized by TIMP-1. MMP-9/TIMP-1 ratio exhibits net activity MMP-9. These thought to have a role in migraine physio-pathogenesis.Total 50 treatment-naive patients (25 with aura 25 without aura) no other diseases, were included. healthy control subjects...
Serum lactic acid and pyruvic levels in patients with migraine tension type headacheObjective: MELAS (mitochondrial encephalopathy, acidosis, stroke-like episodes) syndrome is frequently associated like headaches.The relationship between mitochondrial diseases interesting.Also disorders headache still remain to be investigated.The aim of this report evaluate the serum compare them healthy control group.Methods: We evaluated 30 migraine, control.Lactic samples were measured by biochemical...
Several clinical studies have been conducted to investigate the role of autoantibodies and immunological mechanisms in etiology treatment-resistant epilepsy recent years. Some treatments suggested as a result these studies. In this study, we aimed autoimmunity partial idiopathic generalized determine relationship between drug resistance autoimmune antibodies.Twenty-eight patients (24 treatment-responsive 4 treatment-resistant) with juvenile myoclonic (JME), 26 mesial temporal lobe...
Introduction: Activation of the trigeminovascular system and sensitization brainstem trigeminal nuclei play a significant role in physiopathology migraine.Our aim was to investigate blink reflex (BR) its recovery episodic chronic migraine patients.Methods: Twenty-eight patients, thirty-two without aura patients thirty healthy controls were included study.The study performed using portable electromyography device with software specifically prepared for BR.Blink assessments during painfree...