Betül Baykan
A5084959768- Epilepsy research and treatment
- Migraine and Headache Studies
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Genetics and Neurodevelopmental Disorders
- Trigeminal Neuralgia and Treatments
- EEG and Brain-Computer Interfaces
- Glycogen Storage Diseases and Myoclonus
- Autoimmune Neurological Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Genomics and Rare Diseases
- Long-Term Effects of COVID-19
- Ophthalmology and Eye Disorders
- Ion channel regulation and function
- Neurological disorders and treatments
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Peripheral Neuropathies and Disorders
- Sympathectomy and Hyperhidrosis Treatments
- Transcranial Magnetic Stimulation Studies
- Psychosomatic Disorders and Their Treatments
- COVID-19 and Mental Health
- Vestibular and auditory disorders
- COVID-19 Clinical Research Studies
- Genomic variations and chromosomal abnormalities
Istanbul University
2016-2025
Community Options (United States)
2025
University of Würzburg
2024
University of Southern Denmark
2024
Odense University Hospital
2024
Sapienza University of Rome
2022
National Hospital for Neurology and Neurosurgery
2022
University College London
2022
Cleveland Clinic Lerner College of Medicine
2020
University Medical Center Utrecht
2018
Paroxysmal kinesigenic dyskinesia with infantile convulsions (PKD/IC) is an episodic movement disorder autosomal-dominant inheritance and high penetrance, but the causative genetic mutation unknown.We have now identified four truncating mutations involving gene PRRT2 in vast majority (24/25) of well-characterized families PKD/IC.PRRT2 were also detected 28 78 additional families.PRRT2 encodes a proline-rich transmembrane protein unknown function that has been reported to interact t-SNARE,...
Several studies have shown that the prevalence of migraine and tension-type headache (TTH) varied between different geographical regions. Therefore, there is a need nationwide study for in our country, located Asia Europe. This was designed to estimate 1-year TTH analyse clinical features, impact as well demographic socio-economic characteristics participant households Turkey. We planned investigate 6,000 representative 21 cities Turkey; total 5,323 (response rate 89%) aged 18 65 years were...
Introduction: It is well-known that specific foods trigger migraine attacks in some patients. We aimed to investigate the effect of diet restriction, based on IgG antibodies against food antigens course this randomised, double blind, cross-over, headache-diary trial 30 patients diagnosed with without aura. Methods: Following a 6-week baseline, 266 were detected by ELISA. Then, randomised either excluding or including raised antibodies, individually. 2-week diet-free interval after first...
Genetic generalized epilepsies (GGEs) have a lifetime prevalence of 0.3% and account for 20-30% all epilepsies. Despite their high heritability 80%, the genetic factors predisposing to GGEs remain elusive. To identify susceptibility variants shared across common GGE syndromes, we carried out two-stage genome-wide association study (GWAS) including 3020 patients with 3954 controls European ancestry. dissect syndrome-related variants, also explored two distinct subgroups comprising 1434...
Abstract Background Headache is the most common COVID-19-related neurological symptom. We aimed to reveal diagnostic clues of headache for COVID-19 infection and investigate course primary headaches during pandemic. Methods developed a detailed web-based questionnaire screening characteristics besides clinical features. The participants were grouped according being diagnosed with or not, having previous new-onset headaches. related features their associations other investigated. A binary...
Abstract Background and aim Pathogenesis of COVID-19 -related headache is unknown, though the induction trigeminal neurons through inflammation proposed. We aimed to investigate key systemic circulating inflammatory molecules their clinical relations in patients with headache. Methods This cross-sectional study enrolled 88 patients, hospitalized on a regular ward during second wave pandemic. Clinical characteristics were recorded, laboratory tests studied. Results The mean ages 48 (47.71 ±...
To investigate the predictors of seizure recurrence in women childbearing age with idiopathic generalized epilepsy (IGE) who switched from valproate (VPA) to alternative antiseizure medications (ASMs) and compare effectiveness levetiracetam (LEV) lamotrigine (LTG) as VPA alternatives after switch.
Our aim was to assess the long-term follow-up of juvenile myoclonic epilepsy (JME), with an emphasis on course seizures.We enrolled 48 patients JME (29 F, 19 M; aged 39.9 +/- 9.5 years) followed up for a mean 19.6 5.7 years. The remission 5 years and relapses were evaluated all seizure types changes in severity/frequency myoclonia systematically questioned. clinical EEG features, antiepileptic drug (AED) treatment regimen, systemic psychiatric comorbid diseases evaluated.We found benign...
Sex hormones have some implications on headaches. The objective of the study was to investigate effects hormonal changes comparatively tension-type headache (TTH) and migraine, in a population-based sample. A nationwide face-to-face prevalence conducted using structured electronic questionnaire. 54.3 % migraineurs reported that probability experiencing during menstruation high, whereas 3.9 had only menstruation. Forward logistic regression analysis revealed significant trigger for migraine...
Neuronal antibodies have been identified in patients with seizures as the main or sole symptom. Our aim was to investigate prevalence of these autoantibodies focal epilepsy unknown cause (FEoUC) and group having mesial temporal lobe hippocampal sclerosis (MTLE-HS).We studied anti-neuronal consecutive adult diagnosed FEoUC MTLE-HS our center. The clinical laboratory features antibody-positive were compared those seronegative patients. responses therapy also investigated.Sera from 81 tested....
This study evaluated the EEG findings of patients whose seizures were associated with a possible autoimmune etiology. Our aim was to find clues distinguish antineuronal antibodies (Ab) through studies. We reviewed our database and identified Ab positive epilepsy or without encephalitis. These had Abs N-methyl-d-aspartate receptor (NMDAR) (n = 5), glycine (GLY-R) contactin-associated protein-like 2 (CASPR-2) 4), uncharacterized voltage-gated potassium channel complex (VGKC) antigens 2),...
Headache is a frequent adverse event after viral vaccines. We aimed to investigate the frequency and clinical associations of COVID-19 vaccine-related headache.The characteristics, this headache, main comorbidities, headache history following influenza vaccine during were investigated using web-based questionnaire.A total 1819 healthcare personnel (mean age: 44.4 ± 13.4 years, 1222 females), vaccinated with inactivated virus, contributed survey; 209 (11.4%) had been infected COVID-19. A 556...
After the recent limitations to prescribing valproate, many studies have highlighted challenging management of female patients reproductive age with idiopathic generalized epilepsy (IGE). However, no study, authors' knowledge, has addressed comparative effectiveness alternative antiseizure medications (ASMs) in these patients.
Stiff-person syndrome (SPS) and progressive encephalomyelitis with rigidity myoclonus (PERM) are rare neurologic disorders of the CNS. Until now, exclusive GlyRα subunit-binding autoantibodies subsequent changes in function surface numbers were reported. GlyR have also been described patients focal epilepsy. Autoimmune reactivity against GlyRβ subunits has not yet shown. Autoantibodies GlyRα1 target large extracellular N-terminal domain. This domain shares a high degree sequence homology...
We studied 36 patients (24 males, 12 females), all of whom had definite subacute sclerosing panencephalitis with typical periodic complexes in their electroencephalograms and increased titers measles antibody serum cerebrospinal fluid. Their clinical laboratory findings on admission were reviewed retrospectively. The age at onset symptoms varied from 4 to 23 years. average disease was 13.1 +/- 4.18 mean the duration infection 9 Unusual symptoms, especially early periods disease, included...