- Prenatal Screening and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Preterm Birth and Chorioamnionitis
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Child and Adolescent Health
- Fetal and Pediatric Neurological Disorders
- Prenatal Substance Exposure Effects
- Pregnancy-related medical research
- Gestational Diabetes Research and Management
- Maternal and Perinatal Health Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Cleft Lip and Palate Research
- Cancer, Hypoxia, and Metabolism
- Teratomas and Epidermoid Cysts
- Infant Nutrition and Health
- Fibroblast Growth Factor Research
- Spinal Dysraphism and Malformations
- Pregnancy and Medication Impact
- Genomic variations and chromosomal abnormalities
- Inflammation biomarkers and pathways
- Palliative Care and End-of-Life Issues
Southern Illinois University School of Medicine
2020-2024
Michigan State University
2017-2019
Hurley Medical Center
2016-2019
Wayne State University
2013-2018
Detroit Medical Center
2015-2018
Hutzel Women's Hospital
2013-2015
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2014
Endocan, a dermatan sulphate proteoglycan produced by endothelial cells, is considered biomarker for cell activation/dysfunction. Preeclampsia characterized systemic vascular inflammation, and Therefore, the objectives of this study were to determine whether: (1) plasma endocan concentrations in preeclampsia differ from those uncomplicated pregnancies; (2) changes concentration relate severity preeclampsia, whether these are specific or observed other obstetrical syndromes such as...
The objective of this study is to evaluate pregnancy outcomes in patients with a history wedge resection for interstitial ectopic (WRIEP).Retrospective cohort pregnancies WRIEP from 2000 2013 at two inner city hospitals Detroit, MI. Pregnant-matched controls (1:3) were selected and included surgically treated tubal delivered without pregnancy. Pregnancy outcomes, including composite, compared among the groups.Eighty-three cases identified. Sixty-three (75.9%) underwent which 19 (30.2%) had...
Background: Decidual cast describes the spontaneous sloughing of endometrium as an entire piece while retaining shape endometrial cavity. It may be associated with increased serum progesterone levels and must considered a differential diagnosis in patient who passes tissue per vagina on containing hormonal contraception. Case: A 13-year-old adolescent history menorrhagia since menarche, presented to pediatric emergency room worsening abdominal pain heavy vaginal bleeding stopping her oral...
Secondary postpartum hemorrhage due to an intraperitoneal bleed following a vaginal delivery is extremely rare. We present case of spontaneous rupture the uterine artery normal with delayed presentation, which resulted in significant morbidity. This discusses presentation and management this rare obstetrical emergency. The report also role selective arterial embolization secondary hemorrhage.
To evaluate clinical outcomes of women with singleton pregnancies that underwent intra-amniotic dye instillation (amniodye test) following equivocal diagnosis prelabor rupture membranes (PROM).Records 34 pregnant who amniodye test for PROM were reviewed. Comparisons characteristics, amniotic fluid (AF) cultures, AF interleukin (IL)-6 concentrations, and placenta pathology results between tested positive those negative performed. A sub-analysis test-negative was also performed.(1) Commonest...
To compare optimal visualization of the four-chamber and outflow-tract views fetal heart on sonographic examination between morbidly obese (body mass index [BMI] ≥ 40 kg/m(2) ) nonobese (BMI < 25 pregnant women.In this retrospective cohort study, we included records images from 509 women who had first undergone 18 36 weeks' gestational age.Compared with women, lower views: view, obese, 83/186 (44.6%), versus nonobese, 283/323 (87.6%), 80/186 (43%) 258/290 (89%); p 0.0001 for each comparison....
Objective. The objective of this study was to estimate the time between removal cerclage and delivery, stratified by indication for placement (elective or non-elective). Additionally, delivery within 72 hours after compared elective non-elective placement, as well ultrasound-indicated physical examination-indicated placement. Design. A single-center retrospective cohort study. Participants/Materials, Setting, Methods. Clinical information pregnant women who underwent transvaginal over a...
Mosaic trisomy 17 and mosaic tetraploidy are rare with few cases in literature. has been reported varying clinical features including congenital heart diseases, structural brain anomalies, postaxial polydactyly, FGR, chronic respiratory failure. also variable presentation failure to thrive, developmental delay, microcephaly, dysmorphic facial features. There does not appear be any recorded of an individual both tetraploidy. We report infant whose mother was initially seen prenatally due...
In this retrospective review of 468 mothers with a multi-foetal pregnancy in Detroit, we describe the risk-profiles and obstetrical, maternal foetal outcomes 59 (13%) adolescents. Overall, most were African American, did not have private insurance all unmarried. For mothers, was their first (59.3%) delivery (69.5%). Almost 50% presented to triage at least once during pregnancy. Anaemia (78%) hypertensive disorders (18.6%) common age group. The majority adolescents delivered preterm as 81.4%...
To determine if cardiac axis obtained at an early ultrasound study (11-15 weeks) differs from that a late (18-22 in the same fetus and to evaluate impact of fetal gender and/or maternal body mass index (BMI).Cardiac axes 324 non-anomalous fetuses 11-15 weeks gestation were measured, with follow-up measurements 18-22 weeks. Comparisons performed based on gestational age period, obese/non-obese status.(1) Mean did not change between 11 15 weeks; p = 0.8, (2) mean was more levorotated than 48.1...
INTRODUCTION: The opioid epidemic in continues to be a major public health concern. Opioid use during pregnancy increases risks of adverse neonatal and maternal outcomes, including abstinence syndrome (NAS). Methadone Buprenorphine are used as maintenance therapy for dependence pregnancy. Our objective is compare effects on outcomes. METHODS: This retrospective cohort study that included patients with singleton who received delivered at Hurley Medical Center from 2012 - 2017. IRB approval...
Abstract Monochorionic twin gestations are associated with a greater incidence of neonatal morbidity and mortality when compared their dichorionic counterparts. In turn, monochorionic‐monoamniotic (MCMA) carry risks monochorionic‐diamniotic (MCDA) gestations. While the true spontaneous septostomy dividing membranes (SSDM) in MCDA twins is unknown, SSDM has been demonstrated to be increased mortality, due functional transition from gestation MCMA gestation. We report case mid‐trimester...
The management of a previable pregnancy complicated by severe brain injury raises the question whether to provide somatic support in order maintain or not. Obstetricians who encounter this clinical scenario are faced with emotional, medical and ethical complexities, which require multidisciplinary input. A 19-year-old woman an unremarkable history suffered severe injury remained persistent vegetative state following gunshot wound neck. She was discovered be 15...
BACKGROUND: Pregnant mothers with opioid dependency commonly receive maintenance treatment of (OMT), either as buprenorphine (BMT) or methadone (MMT). We investigated, whether OMT adversely affects standardized neonatal anthropometric outcomes and BMT is potentially safer than MMT in this regard. METHODS: Retrospective chart review mother infant dyad, without OMT. Infant’s absolute ( z-score) at birth were first compared, between control group (negative meconium drug screen), then group....
ABSTRACT We describe the transvaginal sonographic findings in a patient with complete placenta previa and increased risk of preterm birth owing to prior history mid‐trimester pregnancy loss whom we observed short cervix prolapse fetal membranes into endocervical canal. believe that this could lead antepartum hemorrhage mandate close observation when diagnosed. introduced term “placental prolapse” our finding. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound , 43 :122–125, 2015