A5056244517- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Viral Infections and Immunology Research
- Conducting polymers and applications
- Macrophage Migration Inhibitory Factor
- Cardiac Imaging and Diagnostics
- Ion channel regulation and function
- Pharmacological Receptor Mechanisms and Effects
- Advanced battery technologies research
- Receptor Mechanisms and Signaling
- Venous Thromboembolism Diagnosis and Management
- Neuropeptides and Animal Physiology
- ECG Monitoring and Analysis
- Central Venous Catheters and Hemodialysis
Taipei Medical University
2017-2024
Taipei Veterans General Hospital
2018-2023
Wan Fang Hospital
2018-2023
National Yang Ming Chiao Tung University
2019-2020
John Wiley & Sons (United States)
2020
Hudson Institute
2020
Northwestern University
2020
Meenakshi Mission Hospital and Research Centre
2019
Siriraj Hospital
2019
Mahidol University
2019
Accurate identification of slow conducting regions in patients with scar-related atrial tachycardia (AT) is difficult using conventional electrogram annotation for cardiac electroanatomic mapping (EAM). Estimating delays between neighboring sites a potential option activation map computation. We describe our initial experience CARTO 3 Coherent Mapping (Biosense Webster Inc,) the ablation complex ATs.Twenty (58 ± 10 y/o, 15 males) ATs were included. created three-dimensional EAMs system...
Background Acute failure of radiofrequency ablation (RFA) ventricular arrhythmias (VAs) occur in 10%-20% patients and is partly attributed to inadequate lesion depth acquired with standard protocols. Half-normal saline (HNS)-irrigation a promising strategy improve the success rate VA ablation. Objective This study investigated efficacy HNS-irrigated after failed plain normal solution (PNSS)-irrigated on idiopathic outflow tract arrhythmia (OT-VA). Method prospective observational consecutive...
Abstract Background Myocarditis substantially increases the risk of ventricular arrhythmia. Approximately 30% all arrhythmia cases in patients with myocarditis originate from right outflow tract (RVOT). However, role NLRP3 signaling RVOT arrhythmogenesis remains unclear. Methods Rats myosin peptide–induced (experimental group) were treated an inhibitor (MCC950; 10 mg/kg, daily for 14 days) or left untreated. Then, they subjected to electrocardiography and echocardiography. Ventricular tissue...
The management of refractory electrical storm (ES) requiring mechanical circulation support (MCS) remains a clinical challenge in structural heart disease (SHD).The study sought to explore the 30-day and 1-year outcome rescue ablation for ES MCS SHD.A total 81 patients (mean age: 55.3 ± 18.9, 73 men [90.1%]) undergoing were investigated, including 26 with (group 1) 55 without 2). outcome, mortality recurrent ventricular tachyarrhythmias (VAs) receiving appropriate implantable cardioverter...
Macrophage migration inhibitory factor (MIF), a pleiotropic inflammatory cytokine, is highly expressed in patients with atrial fibrillation (AF). Inflammation increases the risk of AF and primarily triggered by pulmonary vein (PV) arrhythmogenesis. This study investigated whether MIF can modulate electrical activity PV examined underlying mechanisms MIF.A conventional microelectrode, whole-cell patch clamp, western blotting, immunofluorescent confocal microscopy were used to investigate...
Thrombosis involving the subclavian vein and superior vena cava is relatively common, especially in cancer patients. Edema of arms head a well-known clinical consequence this thrombosis. The intrinsic risk pulmonary embolism has not been reported previously. Herein, we describe case 63-year-old male patient with extensive stage small cell lung who developed syndrome. Pulmonary thromboembolism was complicated after receiving systemic chemotherapy localized radiotherapy. <Learning objective:...
High-power short-duration (HPSD) and cryoballoon ablation (CBA) has been used for pulmonary vein isolation (PVI).We aimed to compare the efficacy of PVI between CBA HPSD in patients with paroxysmal atrial fibrillation (PAF).We retrospectively analyzed 251 consecutive PAF from January 2018 July 2020. Of them, 124 (mean age 57.2 ± 10.1 year) received 127 59.6 9.4 CBA. In group, radiofrequency energy was set as 50 W/10 s at anterior wall 40 posterior wall. 28 mm generation according...
Most left atrial tachycardia (LAT) is associated with fibrillation (AF). The clinical and electrophysiological characteristics outcomes of LAT without AF have not been investigated. This study sought to determine the long-term ablation predictors recurrence isolated LAT.This a single-center consecutive patients LAT. Atrial arrhythmia was determined from follow-up records who underwent 2008 2017. Clinical electrophysiologic were identified.A total 50 (53 ± 19 years, 46% male) 59 (1.16 0.47...
Abstract Objectives This study aimed to assess the comparative efficacy of four ablation strategies on incidence rates freedom from atrial fibrillation (AF) or tachycardia (AT) through a 3‐year follow‐up in patients with persistent AF. Background The optimal substrate modification using catheter for AF remain unclear. Methods Patients were enrolled consecutively undergo each strategies: (a) Group 1 (Gp 1, n = 69), pulmonary vein isolation (PVI) plus rotor assisted by similarity index and...
cooled ablation catheter in order to enhance the energy delivery into deep tissue.Steam pop is a problem during of seated foci higher energy.RFA from both side outflow septum can be option either alternately using single uRFA or double simultaneously, but later requires two ablators.The configuration circuit was custom modified bRFA circuit, such that instead impedance patch, second designated as grounding connection for active RFA catheter.But distal port decapolar cable and jumper...
The application of new imaging software for the reconstruction left atrium (LA) geometry during atrial fibrillation (AF) ablation has not been well investigated.A total 27 patients undergoing AF using a CARTO Segmentation Module system were studied (phase I). High-density LA mapping PentaRay was merged with computed tomography-based from auto-segmentation module. spatial distortion between two geometries analyzed and compared Registration Match View. associated contact force on shells...
Precordial T-wave inversion (TWI) is an important diagnostic criterion for arrhythmogenic right ventricular cardiomyopathy (ARVC).This study aimed to characterize the initial repolarization features of definite ARVC in patients who first presented with outflow tract arrhythmia (RVOT-VA) and TWI.Patients RVOT-VA TWI ≥ V2 were retrospectively assessed. The characteristics between without a final diagnosis during follow-up compared.TWI was observed 61 553 (mean age: 44.1 ± 14.7 years; 14 men)...
Adrenomedullin, a peptide with vasodilatory, natriuretic, and diuretic effects, may be novel agent for treating heart failure. Heart failure is associated an increased risk of atrial fibrillation (AF), but the effects adrenomedullin on arrhythmogenesis remain unclear. This study investigated whether modulates electrophysiology atria (AF substrate) or pulmonary vein (PV; AF trigger) arrhythmogenesis. Conventional microelectrode whole-cell patch clamps were used to (10, 30, 100 pg/mL)...
Background: Propafenone is a class IC antiarrhythmic agent that commonly used as the first-line therapy for patients with paroxysmal atrial fibrillation (AF) in Taiwan. This study compared efficacy and safety of generic (Rhynorm) brand name (Rytmonorm) propafenone rhythm control AF Methods: was an open-label randomized multicenter noninferior conducted We enrolled 76 AF. To investigate propafenone, we wearable electrocardiogram (ECG) event recorder to evaluate daily burden episodes 24 weeks....
A drug provocation test (DPT) is important for the diagnosis of Brugada syndrome (BrS). The link, however, between dynamic changes electrocardiography (ECG) features after DPT and unstable ventricular arrhythmia (VA) in BrS remains unknown.Between 2014 2019, we assessed 27 patients with (median age: 37.0 [interquartile range, IQR: 22.0-51.0] years; 25 men), including 9 (33.3%) a history VA 18 (66.7%) without. All study presented Brugada-like ECG before DPT. parameters (∆) 12-lead ECGs...