A5054746968- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Acute Myocardial Infarction Research
- Adipokines, Inflammation, and Metabolic Diseases
- ECG Monitoring and Analysis
- Cardiovascular and Diving-Related Complications
- Cardiac Health and Mental Health
- Plant Parasitism and Resistance
- Metabolism, Diabetes, and Cancer
- Agricultural pest management studies
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Natural Antidiabetic Agents Studies
- Neurological disorders and treatments
- Brain Tumor Detection and Classification
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Acute Ischemic Stroke Management
- Traditional and Medicinal Uses of Annonaceae
National Defense Medical Center
2024
Changhua Christian Hospital
2019-2023
Taichung Veterans General Hospital
2012-2023
National Chung Hsing University
2023
National Yang Ming Chiao Tung University
2014-2021
Chang Hua Hospital
2020
Providence University
2018-2020
John Wiley & Sons (United States)
2020
Hudson Institute
2020
Northwestern University
2020
Background: Exercise tolerance and cardiac output have a major impact on the quality of life (QOL) patients experiencing heart failure (HF). Home-based rehabilitation can significantly improve not only exercise but also peak oxygen uptake ( peak), QOL in with HF. The aim this prospective study was to evaluate beneficial effects home-based medical care chronic Methods: This randomized trial. HF left ventricular ejection fraction (LVEF) less than 50% were included study. We randomly assigned...
Abstract Objective Metformin is the standard first-line drug for patients with Type 2 diabetes (T2DM). However, optimal second-line oral anti-diabetic agent (ADA) remains unclear. We investigated cardiovascular risk of various ADAs used as add-on medication to metformin in T2DM from a nationwide cohort. Methods using different after an initial therapy > 90 days were identified Taiwan National Health Insurance Database. Five classes ADAs, including sulphonylureas (SU), glinides,...
Although rare, some paroxysmal atrial fibrillations (AF) still progress despite radiofrequency (RF) ablation. In the study, we evaluated long-term efficacy of RF ablation and predictors AF progression.A total 589 patients (404 men 185 women; aged 54 ± 12 years) who received 3-dimensional mapping were enrolled. Their clinical parameters electrophysiological characteristics collected. They divided into Group 1 (N = 13, with progression) 2 576, no progression). progression was defined as...
Abstract We aimed to investigate the sex-related differences in clinical course of patients with Atrial Fibrillation (AF) enrolled Asia–Pacific-Heart-Rhythm-Society Registry. Logistic regression was utilized relationship between sex and oral anticoagulant, rhythm control strategies 1-year chance maintain sinus rhythm. Cox-regression assess risk all-cause, cardiovascular death, thromboembolic events, acute coronary syndrome, heart failure, major bleeding. In whole cohort (4121 patients, 69 ±...
Both angiotensin-receptor blockers (ARB) and angiotensin-converting enzyme inhibitors (ACEI) have protective effects against atrial fibrillation (AF). The differences between ARB ACEI in their on the primary prevention of AF remain unclear. This study compared combined antihypertensive medications for reducing risk patients with hypertension, determined which was better a nationwide cohort study. Patients aged ≥55 years history hypertension were identified from Taiwan National Health...
Catheter ablation for persistent atrial fibrillation (AF) has shown limited success.To determine whether AF drivers could be accurately identified by periodicity and similarity (PRISM) mapping results when added to pulmonary vein isolation (PVI).This prospective randomized clinical trial was performed between June 1, 2019, December 31, 2020, included patients with enrolled in 3 centers across Asia. Data were analyzed on October 2022.Patients assigned the PRISM-guided approach (group 1) or...
Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of adverse events in patients atrial fibrillation (AF); however, few data are available on this topic Asian populations.
The role of adipokines in the development cardiac syndrome X (CSX) remains unknown.Fifty-nine CSX subjects were retrospectively enrolled from our catheterization databank. Another 54 with valvular heart disease or arrhythmia served as controls. Adipokines measured by ELISA tests.The had lower circulating adiponectin but higher leptin and leptin/adiponectin ratio (×1000) (3.78 ± 4.96 vs. 2.14 5.67, p < 0.001) than those In a multivariate analysis, was predictor CSX, while insulin-resistance...
Abstract Aims Hypertrophic cardiomyopathy (HCM) is an inheritable disease that leads to sudden cardiac death and heart failure (HF). Sarcomere mutations (SMs) have been associated with HF. However, the differences in ventricular function between SM-positive SM-negative HCM patients are poorly characterized. Methods results Of prospectively enrolled 374 unrelated Taiwan, 115 underwent both 91 cardiomyopathy-related gene screening cardiovascular magnetic resonance (45.6 ± 10.6 years old, 76.5%...
The management of refractory electrical storm (ES) requiring mechanical circulation support (MCS) remains a clinical challenge in structural heart disease (SHD).The study sought to explore the 30-day and 1-year outcome rescue ablation for ES MCS SHD.A total 81 patients (mean age: 55.3 ± 18.9, 73 men [90.1%]) undergoing were investigated, including 26 with (group 1) 55 without 2). outcome, mortality recurrent ventricular tachyarrhythmias (VAs) receiving appropriate implantable cardioverter...
The SYNTAX score is an index of coronary severity used to determine the revascularization strategy a patient. Our previous study confirmed that helpful in predicting major adverse cardiac events patients with stable artery disease (CAD). However, few studies have comprehensively investigated predictors for scores CAD, including conventional risk factors, lipid parameters, inflammatory markers and adipokines.The severities 181 revascularization-naïve CAD who had received angiograms were coded...
The data relates to the cohort of patients with atrial fibrillation (AF) from National Health Insurance Research Database Taiwan, "Rhythm Control Better Prevents Stroke and Mortality than Rate Strategies in Patients Atrial Fibrillation - A Nationwide Cohort Study" (Weng et al., press). AF might receive either rate or rhythm control strategy according medication used. baseline groups was included this dataset. Multivariate Cox hazards regression model used evaluate hazard ratio (HR) for major...
Brugada syndrome (BrS) is a heritable sudden cardiac death (SCD) disease with male predominance. Information on gender difference of BrS remains scarce. To investigate the in Han Chinese. We consecutively enrolled 169 patients (153 males and 16 females) from Chinese Taiwan 1998 to 2017. Clinical characteristics, electrocardiographic parameters SCN5A mutation status were compared between genders. The percentage family history SCD females was slightly higher (31.3% vs. 15%, P = 0.15). Females...
as decrease ≥10-20 ms in iQRSd after CRT) on ventricular arrhythmia are controversial. 2In contrast, MRR is associated with significantly improved clinical outcomes. 3The anti-arrhythmic effect of only (only mechanical reverse remodeling) patients moderate-severe HF, however, still 4,5We recently found that both ERR and (ERR+MRR) CRT had more protective effects than only. 6-8It therefore clinically important to predict C ardiac resynchronization therapy (CRT) the standard treatment for heart...
The present study was designed to evaluate the local cardiology infrastructure and services for heart failure (HF) care in Taiwan hospitals compare HF with European countries.Available data from a total of 98 medical centers regional were analyzed. Each facility given single copy questionnaire between September December 2019, service records extracted National Health Insurance Database. adopted 2017 Society Cardiology Atlas.The number cardiologists per million populations 57.4, it lower than...
cooled ablation catheter in order to enhance the energy delivery into deep tissue.Steam pop is a problem during of seated foci higher energy.RFA from both side outflow septum can be option either alternately using single uRFA or double simultaneously, but later requires two ablators.The configuration circuit was custom modified bRFA circuit, such that instead impedance patch, second designated as grounding connection for active RFA catheter.But distal port decapolar cable and jumper...
Introduction High beat-to-beat morphological variation (divergence) on the ventricular electrogram during programmed stimulation (PVS) is associated with increased risk of fibrillation (VF), unclear mechanisms. We hypothesized that divergence epicardial wavebreaks PVS, and it predicts VF occurrence. Method results Langendorff-perfused rabbit hearts (n = 10) underwent 30-min therapeutic hypothermia (TH, 30°C), followed by a 20-min treatment rotigaptide (300 nM), gap junction modifier....