A5067822876- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Dementia and Cognitive Impairment Research
- Cardiovascular and exercise physiology
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Effects of Exercise
- Ion channel regulation and function
- Neurological disorders and treatments
- Male Reproductive Health Studies
- Medical Image Segmentation Techniques
- Sperm and Testicular Function
- Artificial Intelligence in Healthcare
- Medication Adherence and Compliance
- Steroid Chemistry and Biochemistry
- ECG Monitoring and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Machine Learning in Healthcare
- Health and Wellbeing Research
National Yang Ming Chiao Tung University
2014-2025
National Yang Ming University Hospital
2012-2023
Heart Rhythm Society
2017
Taipei Veterans General Hospital
2001-2012
Cardiovascular Institute Hospital
2009-2010
National Health Insurance Service Ilsan Hospital
2007
Mackay Memorial Hospital
2005-2006
Kuang Tien General Hospital
2005-2006
Wan Fang Hospital
2005
Kaohsiung Medical University Chung-Ho Memorial Hospital
2005
Document Reviewers: Carina Blomström-Lundqvist, MD, PhD; Angelo A.V. De Paola, Peter M. Kistler, MBBS, Gregory Y.H. Lip, MD; Nicholas S. Peters, Cristiano F. Pisani, Antonio Raviele, Eduardo B. Saad, Kazuhiro Satomi, Martin K. Stiles, MB ChB, Stephan Willems, PhD During the past three decades, catheter and surgical ablation of atrial fibrillation (AF) have evolved from investigational procedures to their current role as effective treatment options for patients with AF. Surgical AF, using...
Introduction: Some conflicting results of the efficacy inducibility test used in catheter ablation atrial fibrillation (AF) have been reported. The aim this study was to investigate and circumferential with pulmonary vein isolation (PVI) patients paroxysmal AF its relationship substrate. Methods Results: This consisted 88 who underwent ablation. Electroanatomic mapping using a NavX system performed biatrial voltage obtained during sinus rhythm. After successful PVI, an determine requirement...
PV Stenosis after AF Ablation. Introduction: Elimination of the initiating focus within pulmonary vein (PV) using radiofrequency (RF) catheter ablation is a new treatment modality for drug‐refractory atrial fibrillation. However, information on long‐term safety RF limited. Methods and Results: In 102 patients with fibrillation at least one from PV, series transesophageal echocardiography was performed to monitor effect PV. There were 66 foci in right upper 65 left Within 3 days ablation, 26...
Pulmonary Vein Dilation in AF. Introduction: The positive relationship between left atrial (LA) size and fibrillation (AF) is well recognized; however, there little information on the association of pulmonary vein (PV) diameter purpose this study was to investigate by magnetic resonance angiography change PV LA patients with no history AF, paroxysmal AF (PAF), chronic (CAF). Methods Results: included 47 patients. Group I 15 normal sinus rhythm documented II 24 drug‐refractory PAF who...
Introduction: Understanding the structural remodeling and reverse of left atrium (LA) pulmonary vein (PV) after radiofrequency ablation atrial fibrillation (AF) may provide important insights into mechanism management AF. This study used magnetic resonance angiographic (MRA) images to investigate changes in PV LA morphologies before more than 1 year ablation. Method Results: Forty‐five patients (36 men 9 women, mean age 60 ± 13 years) who underwent MRA 12 months (mean 21 11) paroxysmal AF...
Introduction: The atrial substrate plays an important role in the maintenance of fibrillation (AF). Further investigation biatrial may be helpful for understanding mechanism AF. aim this study was to investigate properties right and left (RA LA) AF patients their impact on catheter ablation. Methods: Biatrial electroanatomic mapping using a three‐dimensional system (NavX) performed 117 consecutive with paroxysmal (n = 99) persistent 18) voltage total activation time (TAT) were obtained...
Atrial substrate properties have been demonstrated to be related atrial arrhythmias. This study investigated whether the exhibits progressive remodeling in patients with recurrence of fibrillation (AF) after catheter ablation.Fifteen consecutive AF (52 +/- 12 years old, males) underwent same mapping technique (NavX, St. Jude Medical, Minnetonka, MN, USA) and ablation for primary (170 66 days first procedure). The bipolar mean peak-to-peak voltage (PPV) global left atrium during sinus rhythm...
Introduction: The left atrium (LA) ablation in different regions, including LA appendage (LAA), roof, and septum, has recently been proposed to improve the success rate of treating patients with atrial fibrillation (AF). purpose this study was investigate anatomy LAA, using computed tomography (CT). Methods Results: Multidetector CT scan used depict 47 drug‐refractory paroxysmal AF (39 males, age = 50 ± 12 years) 49 control subjects (34 54 11 years). area LAA orifice, neck, length roof line...
Long‐Term Outcome of NPV AF Ablation . Introduction: Data regarding the long‐term outcome catheter ablation in patients with nonpulmonary vein (NPV) ectopy initiating atrial fibrillation (AF) are limited. We aimed to evaluate result who had triggers and underwent ablation. Methods Results: The study included 660 consecutive (age 54 ± 11 years old, 477 males) undergone for AF. Group 1 consisted 132 from NPV, group 2 528 pulmonary (PV) only. Patients were younger than those (51 12 old vs P =...
Right Middle Pulmonary Vein and AF. Introduction: Elimination of the ectopic foci from pulmonary veins (PVs) has proved to be a curative therapy for focal atrial fibrillation (AF). However, information about importance right middle PV (RMPV) in initiation AF radiofrequency ablation is limited. Method Results: Forty‐three patients (34 men 9 women; age 65 ± 12 years) with drugrefractory paroxysmal underwent electrophysiologic study catheter treatment Three‐dimensional magnetic resonance...
Objectives and Background: The success rate of achieving electrical isolation by circumferential pulmonary vein ablation (CPVA) varies from 32% to 88%. We carried out at the carina evaluate elimination rates potentials (PVPs) after one round CPVA had failed eliminate all PVPs in patients with atrial fibrillation (AF). Methods: Ninety‐seven (75 males; mean age: 50 ± 12 years; 15 persistent AF 82 paroxysmal AF) who underwent catheter were analyzed. All PVP as endpoint. electrophysiology...
The impact of non-sustained ventricular tachycardia (NSVT) on the risk thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate association between NSVT outcomes.The population 5903 was culled from "Registry 24-hour ECG monitoring at Taipei Veterans General Hospital" (REMOTE database) January 1, 2002 December 31, 2004. Of that total, we enrolled 3767 sustained tachycardia, disease, permanent pacemaker. For...
Introduction: The mechanisms of late (<1 year after the ablation) and very (>1 recurrences paroxysmal atrial fibrillation (AF) catheter ablation have not been reported. Methods Results: Fifty consecutive patients undergoing a repeated electrophysiologic study to investigate recurrence AF first were included. Group 1 consisted 12 with (26 ± 13 months) group 2 38 (3 3 AF. In baseline study, had lower incidence foci from pulmonary veins (PVs) (67% vs 92%, P = 0.048) higher right atrium...
Coronary artery disease (CAD) is an important etiology of atrial fibrillation (AF). calcification a marker coronary atherosclerosis and events. The purpose this study was to investigate whether larger left atrium (LA) pulmonary veins (PVs) were seen by multidetector computed tomography (MDCT) scans in those patients with higher calcium scores.A total 166 undergoing MDCT for general check-up (n = 128, 77%) or suspected CAD 38, 23%) enrolled divided into control (calcium score 0, n 60), medium...
Previous studies have indicated that atrial fibrillation (AF) in patients over the age of 60 at diagnosis is a risk factor for substantial increase cardiovascular events. However, information about impact on substrate and clinical outcome after catheter ablation AF limited.This study included 350 (53 ± 12 years, 254 males) who underwent circumferential pulmonary vein isolation (CPVI) AF, guided by NavX mapping system. The subjects were divided into three groups according to their age, as...
Background: The left atrial (LA) size is an important predictor of fibrillation (AF) procedural termination and the long‐term outcome. We sought to evaluate outcome in regard LA termination. Methods: Eighty‐seven consecutive chronic AF patients (72 males, 53 ± 10 years) underwent 3D mapping (NavX) ablation. A stepwise approach including circumferential pulmonary vein (PV) isolation, linear ablation, continuous complex‐fractionated electrogram (CFE) ablation (targeting fractionation intervals...
Long‐Term Outcome of SVC AF Ablation. Introduction: Data the long‐term clinical outcome after superior vena cava (SVC) isolation are limited. We aimed to evaluate in patients with atrial fibrillation (AF) who had triggers originating from and received catheter ablation AF. Methods Results: The study consisted 68 (age 56 ± 12 years old, 32 males) underwent procedure for drug‐refractory, symptomatic paroxysmal since 1999. Group 1 37 initiated only, group 2 31 both pulmonary vein (PV) triggers....
The recurrence of atrial fibrillation (AF) is not uncommon in the era catheter ablation. This study aimed to evaluate characteristics AF patients who underwent multiple (>2) ablation procedures.Of 666 consecutive (53 ± 11 y/o, 484 men) (paroxysmal AF, n = 530), 144 (22%) 2 procedures and 52 (8%) more than due symptomatic recurrences refractory medication during 48 23 months follow-up. Baseline procedural at index procedure were investigated determine their impact on necessity procedures....
An artificial intelligence (AI)-enabled electrocardiogram (ECG) model has been developed in a healthy adult population to predict ECG biological age (ECG-BA). This ECG-BA exhibited robust correlation with chronological (CA) adults and additionally significantly enhanced the prediction of aging-related diseases' onset subclinical diseases. The showed particularly strong predictive power for cardiovascular non-cardiovascular diseases such as stroke, coronary artery disease, peripheral arterial...
Introduction: High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most the recurrences occur within 6 months after ablation. The characteristics very late recurrent AF (>12 ablation) have not been reported. Methods and Results: Two hundred seven patients drug‐refractory underwent successful focal or isolation foci. After first procedure, Holter monitoring event recorders were used to evaluate symptomatic AF. A second procedure was...
Atrial tachycardia (AT), including focal and reentrant AT, can occur after circumferential pulmonary vein isolation (CPVI). The aim of this study was to investigate the electrophysiological characteristics induced AT its clinical outcome.In our series 160 patients with paroxysmal atrial fibrillation (AF), 45 ATs were by high-current burst pacing CPVI in 26 patients. All mapped using a three-dimensional (3D) mapping system. Noninducibility endpoint ablation AT. Gap-related considered if...
Gender Differences in Patients With AVNRT. Introduction: The detailed electrophysiological characteristics of the gender differences associated with atrioventricular nodal reentrant tachycardia (AVNRT) have not been clarified. This study investigated gender‐related a large series patients undergoing radiofrequency catheter ablation. Methods and Results: A total 2,088 consecutive AVNRT (men/women 869/1,219) who underwent ablation were enrolled this study. We evaluated their characteristics....
Introduction: Left atrial (LA) isthmus ablation was reported to improve the success rate of catheter paroxysmal fibrillation (AF). LA could also cure a subset flutter. Therefore, understanding anatomy is important for performing effectively. Methods and Results: Group I included 45 patients (40 male, mean age = 50 ± 13 years) with AF who underwent ablation. II (37 54 10 without history AF. They 16‐slice multidetector computed tomography (MDCT) scan delineate structures before procedure. The...