A5006803964- Immunotherapy and Immune Responses
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Glycosylation and Glycoproteins Research
- Acute Kidney Injury Research
- Bacteriophages and microbial interactions
- Chronic Kidney Disease and Diabetes
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Research Studies
- Heart Failure Treatment and Management
- Cancer Research and Treatments
- Cardiac Arrest and Resuscitation
- Blood Pressure and Hypertension Studies
- Cerebrovascular and Carotid Artery Diseases
- Mycobacterium research and diagnosis
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Heart rate and cardiovascular health
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetes Treatment and Management
University of Georgia
2022-2024
Palmerston North Hospital
2024
Whakatane Hospital
2022
Hospital del Niño
2020-2021
SingHealth
2013-2017
Ng Teng Fong General Hospital
2016-2017
Taipei Veterans General Hospital
2012-2016
Alexandra Hospital
2008-2016
Singapore General Hospital
2016
National University Hospital
2007-2015
Racotumomab-alum is an anti-idiotype vaccine targeting the NeuGcGM3 tumor-associated ganglioside. This clinical trial was conducted to provide a preliminary estimate of efficacy and safety racotumomab as switch maintenance for patients with advanced non-small cell lung cancer (NSCLC).Patients stage IIIb/IV NSCLC who have at least stable disease after first-line chemotherapy were randomized 1:1 racotumomab-alum (5 immunizations every 2 weeks re-immunizations 4 weeks) or placebo. Treatment...
Long‐Term Outcome of NPV AF Ablation . Introduction: Data regarding the long‐term outcome catheter ablation in patients with nonpulmonary vein (NPV) ectopy initiating atrial fibrillation (AF) are limited. We aimed to evaluate result who had triggers and underwent ablation. Methods Results: The study included 660 consecutive (age 54 ± 11 years old, 477 males) undergone for AF. Group 1 consisted 132 from NPV, group 2 528 pulmonary (PV) only. Patients were younger than those (51 12 old vs P =...
Patients with diabetes mellitus have worse long-term outcomes after acute myocardial infarction (AMI) than non-diabetics. This may be related to differential contribution of neutrophil and lymphocyte inflammation during AMI in diabetics vs. We aim determine the predictive value neutrophil-to-lymphocyte ratio (NLR) for major adverse events post-AMI Type 2 non-diabetics.A total 2559 consecutive patients admitted (61 ± 14 years, 73% male 43% diabetic) were analyzed. A complete blood count was...
Background The prognostic significance of premature atrial complex ( PAC ) burden is not fully elucidated. We aimed to investigate the relationship between s and long‐term outcome. Methods Results investigated clinical characteristics 5371 consecutive patients without fibrillation AF or a permanent pacemaker PPM at baseline who underwent 24‐hour electrocardiography monitoring January 1, 2002, December 31, 2004. Clinical event data were retrieved from Bureau National Health Insurance Taiwan....
We aim to examine the risk predictors of contrast-induced nephropathy (CIN) in patients with normal baseline serum creatinine (Cr). CIN is an important complication postpercutaneous coronary intervention (PCI). Previous studies examined chronic renal impairment. No large investigated function which constitute majority undergoing PCI. identify this cohort and clinical outcomes.A total 3036 Cr (<1.5 mg/dL) who did not receive prophylaxis while PCI were enrolled. occurrence mortality outcome at...
Background: Contrast nephropathy (CIN) increases adverse clinical outcomes. We examine risks and predictors of CIN in patients undergoing percutaneous coronary intervention (PCI) effectiveness prophylactic therapy. Methods: A cohort 8,798 who underwent PCI from May 2000 to April 2008 was enrolled. divided into 3 groups. A: STEMI patient primary PCI; B: UA/NSTEMI early C: Patients without MI elective PCI. Pre‐PCI saline hydration given group B C if baseline glomerular filtration rate (GFR)...
Background This study explored the relationship between glycated hemoglobin (HbA1c) level in patients with or without diabetes mellitus and future risks of cardiovascular disease death. Methods Based on a national representative cohort, total 5277 participants (7% diabetes) were selected from Taiwan's Triple High Survey 2002. The comorbidities, medication usages, outcomes death, extracted Taiwan’s National Health Insurance Research Database Death Registry. Results After median follow-up 9.7...
Background Heart failure (HF) is a global health problem. Guidelines for the management of HF have been established in Western countries and Taiwan. However, data from Taiwan Society Cardiology-Heart Failure with reduced Ejection Fraction (TSOC-HFrEF) registry showed suboptimal prescription guideline-recommended medications. We aimed to analyze reason non-prescription clinical outcomes as result under-prescription Methods A total 1509 patients hospitalized acute HFrEF were recruited 21...
The optimal substrate ablation approach in patients with persistent atrial fibrillation (Per AF) remains unclear. This was a prospective randomized study comparing the efficacy of limited (continuous complex fractionated electrogram, CFAE: <60 milliseconds) versus extensive CFAE plus variable <120 modification Per AF patients.We enrolled 120 study, and 30 termination after pulmonary vein isolation (PVI) were excluded. In remaining 90 patients, 45 treated (Group 1) an 2). end point incidence...
Rhodiola, a popular plant in Tibet, has been proven to decrease arrhythmia. The aim of this study was elucidate the molecular mechanism and electrophysiological properties rhodiola suppression atrial fibrillation.This consisted 3 groups as follows: Group 1: normal control rabbits (n = 5); 2: with heart failure (HF) created by coronary ligation who received 2 weeks water orally placebo 3: HF 270 mg/kg/day treatment 5). monophasic action potential, histology, real-time polymerase chain...
Background: Endothelial progenitor cell (EPC) capture stent is designed to promote rapid endothelization and healing potentially useful in patients undergoing primary percutaneous coronary intervention ( PCI) for acute myocardial infarction (AMI). We studied the intermediate‐term efficacy safety of EPC compared that with sirolimus‐eluting bioabsorbable polymer (CURA) bare metal (BMS) AMI patients. Methodology: Patients presenting who underwent PCI respective stents between January 2004 June...
Recent studies suggest that obstructive sleep apnea (OSA) causes thoracic aortic dilatation; but it is well accepted hypertension can cause dilatation, and a common finding in patients with OSA. We aimed to investigate the relative impact of OSA on structural functional changes aorta.This was an echocardiography substudy our prospective study acute myocardial infarction (AMI). Ninety-four male who completed both polysomnography were recruited. defined as apnea-hypopnea index (AHI) > or =...