A5010438868- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Medicinal Plants and Bioactive Compounds
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Streptococcal Infections and Treatments
- Biomarkers in Disease Mechanisms
- Cardiac Fibrosis and Remodeling
- Ion Channels and Receptors
- Cardiovascular Effects of Exercise
- Artificial Intelligence in Healthcare
- Pharmaceutical Practices and Patient Outcomes
- Restless Legs Syndrome Research
- Pericarditis and Cardiac Tamponade
- Medication Adherence and Compliance
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Adipose Tissue and Metabolism
- Healthcare Systems and Public Health
- Signaling Pathways in Disease
- Paraoxonase enzyme and polymorphisms
- Mitochondrial Function and Pathology
- Pharmacological Effects of Natural Compounds
- Apelin-related biomedical research
Taipei Medical University-Shuang Ho Hospital
2011-2024
Taipei Medical University
2021-2024
Taipei Veterans General Hospital
2011-2023
National Yang Ming Chiao Tung University
2015
Rhodiola, a popular plant in Tibet, has been proven to decrease arrhythmia. The aim of this study was elucidate the molecular mechanism and electrophysiological properties rhodiola suppression atrial fibrillation.This consisted 3 groups as follows: Group 1: normal control rabbits (n = 5); 2: with heart failure (HF) created by coronary ligation who received 2 weeks water orally placebo 3: HF 270 mg/kg/day treatment 5). monophasic action potential, histology, real-time polymerase chain...
The atrial substrate in chronic fibrillation (AF) patients with a left spontaneous echo contrast (LASEC) has not been previously reported. aim of this study was to investigate the properties and long-term follow-up results who received catheter ablation AF.Of 36 consecutive AF stepwise approach, 18 an LASEC (group I) were compared age-gender-left volume matched without II). including weighted peak-to-peak voltage, total activation time during sinus rhythm (SR), dominant frequency (DF),...
Electromechanical Interval and Paroxysmal Atrial Fibrillation. Introduction: It is difficult to discriminate patients with without paroxysmal atrial fibrillation (PAF). The electromechanical interval determined by the transthoracic echocardiogram demonstrated be a predictor of new onset AF. aim our study was investigate whether useful parameter identify PAF. Methods Results: A total 297 (PAF group = 103; control 194) mean age 59.4 ± 12.4 years were enrolled. (PA-PDI) defined as time from...
Sleep deprivation (SD) is a recognized risk factor for atrial fibrillation (AF), yet the precise molecular and electrophysiological mechanisms behind SD-induced AF are unclear. This study explores electrical structural changes that contribute to in chronic partial SD. We induced SD Wistar rats using modified multiple-platform method. Echocardiography demonstrated impaired systolic diastolic function left ventricle (LV) of rats. The exhibited an elevated heart rate higher low-frequency...
Rapid eye movement (REM) sleep deprivation triggers mania and induces cardiac fibrosis. Beyond neuroprotection, lithium has cardioprotective potential antifibrotic activity. This study investigated whether improved REM deprivation-induced dysfunction evaluated the mechanisms. Transthoracic echocardiography, histopathological analysis, Western blot analysis were performed in control sleep-deprived rats with or without treatment (LiCl of 1 mmol/kg/day administered by oral gavage for 4 weeks)...
Acetyl‑CoA carboxylase 2 plays a crucial role in regulating mitochondrial fatty acid oxidation cardiomyocytes. Lithium, monovalent cation known for its cardioprotective potential, has been investigated influence on bioenergetics. The present study explored whether lithium modulated acetyl‑CoA and metabolism cardiomyocytes the potential therapeutic applications of alleviating metabolic stress. Mitochondrial bioenergetic function, oxidation, reactive oxygen species production, membrane...
A 75-year-old woman was admitted because of acute chest pain for one day. The electrocardiogram (ECG) showed progressive decreasing R wave amplitudes with new QS waves at precordial leads in three hours (Figure 1 A, B). Serial high-sensitivity cardiac troponin testing baseline and after admission were within normal range (8.8 pg/mL 11.1 respectively. Upper reference limit: 17.5 pg/mL). white-cell count 6800 /µL (reference range: 4800 to 10,800). contrast-enhanced computer tomography no...
Abstract Background Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia. Recently, there a new scoring system - 4S (Stroke Risk; Symptoms; Severity of Burden; Substrate), proposed in 2020 European Society Cardiology AF guideline to identify characteristics patients details and provide precise guidance for management. Purpose We aimed report disease severity who received first time catheter ablation (CA) using 4S-AF system, further discover value scheme prediction atrial...