Yun‐Yu Chen

ORCID: 0000-0001-7009-7838
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Effects of Exercise
  • Cardiac pacing and defibrillation studies
  • Diabetes Treatment and Management
  • Diabetes Management and Research
  • Cardiovascular Function and Risk Factors
  • Fatty Acid Research and Health
  • Plant Ecology and Soil Science
  • Sports injuries and prevention
  • Alcohol Consumption and Health Effects
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Health Systems, Economic Evaluations, Quality of Life
  • Ethics in Business and Education
  • Heart Rate Variability and Autonomic Control
  • Eicosanoids and Hypertension Pharmacology
  • Parkinson's Disease Mechanisms and Treatments
  • Diet and metabolism studies
  • Acute Myocardial Infarction Research
  • Long-Term Effects of COVID-19
  • Bacterial Infections and Vaccines
  • Helicobacter pylori-related gastroenterology studies
  • Central Venous Catheters and Hemodialysis

Taichung Veterans General Hospital
2023-2025

Taipei Veterans General Hospital
2015-2025

National Yang Ming Chiao Tung University
2016-2025

National Chung Hsing University
2024-2025

National Taiwan University
2014-2024

National Cheng Kung University
2020

National Yang Ming University Hospital
2016

Jinan University
2012

De novo lipogenesis (DNL) is the primary metabolic pathway synthesizing fatty acids from carbohydrates, protein, or alcohol. Our aim was to examine associations of in vivo levels selected (16:0, 16:1n7, 18:0, 18:1n9) DNL with incidence type 2 diabetes (T2D).Seventeen cohorts 12 countries (7 Europe, 7 United States, 1 Australia, Taiwan; baseline years = 1970-1973 2006-2010) conducted harmonized individual-level analyses DNL-related incident T2D. In total, we evaluated 65,225 participants...

10.1371/journal.pmed.1003102 article EN cc-by PLoS Medicine 2020-06-12

AimsIt is not known if successful catheter ablation for atrial fibrillation (AF) improves the patient's long-term cardiovascular outcomes. This study investigated outcomes and mortality of AF patients at high risk who received antiarrhythmic medication ablation.

10.1093/europace/eus336 article EN EP Europace 2012-11-28

Background The prognostic significance of premature atrial complex ( PAC ) burden is not fully elucidated. We aimed to investigate the relationship between s and long‐term outcome. Methods Results investigated clinical characteristics 5371 consecutive patients without fibrillation AF or a permanent pacemaker PPM at baseline who underwent 24‐hour electrocardiography monitoring January 1, 2002, December 31, 2004. Clinical event data were retrieved from Bureau National Health Insurance Taiwan....

10.1161/jaha.115.002192 article EN cc-by-nc-nd Journal of the American Heart Association 2015-08-28

This study investigated the epidemiological characteristics of new-onset dementia in patients with atrial fibrillation (AF) and association catheter ablation different subtypes dementia.We conducted a population-based, retrospective cohort using data from Taiwan National Health Insurance Research Database. In total, 136 774 without history were selected after 1:1 propensity score matching based on age (with AF vs. AF). A competing risk model was used to investigate three dementia:...

10.1093/europace/euad109 article EN cc-by-nc EP Europace 2023-04-25

Sodium-glucose co-transporter 2 inhibitors (SGLT2i) enhance cardiovascular outcomes in individuals with type diabetes mellitus (T2DM). Whether such effects also occur T2DM patients atrial fibrillation (AF) remains unknown. We aimed to investigate SGLT2i use on concomitant AF and T2DM. Patients both were identified from TriNetX, an international electronic medical record. Participants divided into groups according their of SGLT2i, at a 1:1 distribution through propensity score matching (PSM)....

10.1210/clinem/dgae861 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2025-02-25

Background This study explored the relationship between glycated hemoglobin (HbA1c) level in patients with or without diabetes mellitus and future risks of cardiovascular disease death. Methods Based on a national representative cohort, total 5277 participants (7% diabetes) were selected from Taiwan's Triple High Survey 2002. The comorbidities, medication usages, outcomes death, extracted Taiwan’s National Health Insurance Research Database Death Registry. Results After median follow-up 9.7...

10.1371/journal.pone.0123116 article EN cc-by PLoS ONE 2015-04-13

The long-term clinical impact of premature ventricular complexes (PVCs) on mortality and morbidity has not been fully studied. This study aimed to investigate the association between burden PVCs adverse outcome. A total 5778 subjects, who were pacemaker-free tachycardia-free at baseline, received 24-hour electrocardiography monitoring January 1, 2002 December 31, 2004. Clinical event data retrieved from Bureau National Health Insurance Taiwan. Multivariate Cox hazards regression models...

10.1097/md.0000000000005476 article EN cc-by-nc Medicine 2017-01-01

Gender differences in the penetrance and clinical expression of genetic mutations have been reported patients with arrhythmogenic right ventricular (RV) dysplasia/cardiomyopathy (ARVD/C). Our study aimed at clarifying impact gender on substrates outcomes after radiofrequency catheter ablation (RFCA).Patients ARVD/C underwent RFCA for drug-refractory arrhythmias (VAs) were consecutively enrolled. Baseline characteristics, electrocardiograms, substrates, VA recurrences extracted comparison...

10.1016/j.ijcard.2016.11.055 article EN cc-by-nc-nd International Journal of Cardiology 2016-11-08

This study investigated whether initial SGLT2 (sodium-glucose cotransporter 2) inhibitor-based treatment is superior to metformin-based regimens as a primary prevention strategy among low-risk patients with diabetes.

10.1161/jaha.123.032397 article EN cc-by-nc-nd Journal of the American Heart Association 2024-04-09

Whether the distribution of scar in arrhythmogenic right ventricular cardiomyopathy (ARVC) plays a role predicting different types arrhythmias is unknown. This study aimed to investigate prognostic value patients with ARVC.We studied 80 consecutive ARVC (46 men, mean age 47 ± 15 years) who underwent an electrophysiological ablation. Thirty-four receive both endocardial and epicardial mapping. Abnormal substrates were characterized. Three groups defined according gradient (<10%: transmural,...

10.1093/europace/euw393 article EN EP Europace 2016-11-08

The incidence of acute myocarditis complicated with ventricular tachycardia (VT) is unknown. This study aimed to investigate the association between and VT mortality. We also determine independent predictors that increased risk in those patients. From 2000 2004, 13,250 patients a history were identified from Taiwan National Health Insurance Research Database. same number individuals without heart disease matched sex underlying diseases selected as control group. long-term risks...

10.1097/md.0000000000006633 article EN cc-by-nc Medicine 2017-05-01

This study investigated the feasibility of using precordial surface ECG lead interlead QRS dispersion (IQRSD) in identification abnormal ventricular substrate arrhythmogenic right cardiomyopathy (ARVC).Seventy-one consecutive patients were enrolled and reclassified into 4 groups: definite ARVC with epicardial ablation (Group 1), tachycardia (VT, Group 2), idiopathic outflow tract VT without 3), controls 4). IQRSD was quantified by angular difference between reconstruction vectors obtained...

10.1371/journal.pone.0182364 article EN cc-by PLoS ONE 2017-08-03

Background: Pulmonary embolism (PE) is frequently associated with cancer. This study aimed to assess patients acute PE and identify diagnostic predictors of new cancer after 1 year follow-up. Methods: One hundred twenty-one were enrolled consecutively from the emergency department a single medical center in Taiwan. Data computed tomography angiography, echocardiogram, electrocardiogram for baseline comorbidities, clinical presentation, laboratory parameters recorded. The surviving discharged...

10.1097/jcma.0000000000000259 article EN cc-by-nc-nd Journal of the Chinese Medical Association 2020-01-16

The long-term outcomes of radiofrequency catheter ablation (RFCA) in patients with Wolff-Parkinson-White syndrome (WPW) remain unclear. We investigated the impact RFCA on risk coronary events and mortality WPW patients.We conducted a prospective cohort study utilizing Taiwan National Health Insurance Research Database. Between 2000 2003, no prior artery disease (CAD) history, aged over 18 years, who underwent were identified. without matched propensity-score 1:4 matching for confounding...

10.1093/europace/eux115 article EN EP Europace 2017-06-10

Left ventricular (LV) systolic strain is presumably a more sensitive myocardial indicator than LV ejection fraction (LVEF). Data regarding the use of in clinical risk stratification and identifying angiotensin receptor-neprilysin inhibitor (ARNi) responders remain scarce heart failure with mildly reduced (HFmrEF). The authors aimed to examine whether assessing may provide prognostic insight beyond LVEF help discriminate therapeutic efficacy ARNi HFmrEF patients. were quantified among 1,075...

10.1016/j.jacadv.2023.100654 article EN cc-by-nc-nd JACC Advances 2023-11-01
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