A5063899324- Intracranial Aneurysms: Treatment and Complications
- Nerve injury and regeneration
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Mesenchymal stem cell research
- Neurogenesis and neuroplasticity mechanisms
- Spinal Cord Injury Research
- RNA Interference and Gene Delivery
- Cardiovascular Health and Disease Prevention
- Facial Nerve Paralysis Treatment and Research
- Neuroscience and Neuropharmacology Research
- Facial Trauma and Fracture Management
- Cerebral Venous Sinus Thrombosis
- Cervical and Thoracic Myelopathy
- Trigeminal Neuralgia and Treatments
- Vascular Malformations Diagnosis and Treatment
- Vestibular and auditory disorders
- Genetic diversity and population structure
- Oropharyngeal Anatomy and Pathologies
- Neurological Complications and Syndromes
- Botulinum Toxin and Related Neurological Disorders
- Moyamoya disease diagnosis and treatment
- Cancer, Hypoxia, and Metabolism
- Spinal Fractures and Fixation Techniques
Chungnam National University
2018-2024
Inha University Hospital
2006-2023
Inha University
2006-2018
National Evidenc- based healthcare Collaborating Agency
2018
Shanghai Cell Therapy Research Institute
2009
University of Sheffield
2007
Incheon Medical Center
2007
Abstract To assess the safety and therapeutic efficacy of autologous human bone marrow cell (BMC) transplantation administration granulocyte macrophage-colony stimulating factor (GM-CSF), a phase I/II open-label nonrandomized study was conducted on 35 complete spinal cord injury patients. The BMCs were transplanted by injection into surrounding area site within 14 days (n = 17), between 8 weeks 6), at more than 12) after injury. In control group, all patients 13) treated only with...
Abstract Granulocyte–macrophage colony‐stimulating factor (GM‐CSF) is a hematopoietic cytokine that has the potential for clinical application. The biological effects of GM‐CSF have been well characterized, and include stimulation bone marrow stem cell proliferation inhibition apoptosis cells. In contrast, therapeutic on central nervous system in acute injury such as stroke spinal cord reported only recently. To better understand protective effect dopaminergic neurons Parkinson’s disease...
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a potent hematopoietic growth that both enhances the survival and drives differentiation proliferation of myeloid lineage cells. Recent studies have suggested GM-CSF has neuroprotective effect against CNS injury. In this paper, authors investigated on neuron locomotor behavior in rat model focal cerebral ischemic injury.To understand its vitro, was administered to glutamate-induced excitotoxicity neuronal injury cell culture mimics...
Object Vascular endothelial growth factor (VEGF) has been investigated as a therapy for many disorders and injuries involving ischemia. In this report, we constructed evaluated hypoxia-inducible VEGF expression system treatment spinal cord injury (SCI). Methods The plasmid was using the erythropoietin (Epo) enhancer with Simian virus 40 (SV40) promoter (pEpo-SV-VEGF) or RTP801 (pRTP801-VEGF). of in vitro after transfection into N2A cells. plasmids were then injected rat cords contusion...
Objective: Decompressive craniectomy (DC) is a useful surgical method to achieve adequate decompression in hypertensive intracranial patients.This study suggested new skin incision for DC, and analyzed its efficacy safety.Methods: In the retrograde reviews, 15 patients underwent newly approach using n-shape technique (Group A) 23 were treated with conventional question mark B).Two groups compared terms of decompressed area craniectomy, protruded brain volume out skull layer, operation time...
The purpose of this study was to evaluate and compare the long-term effects carotid endarterectomy (CEA) artery stenting (CAS) on blood pressure (BP).Between January 2003 December 2009, 134 patients underwent 145 procedures for treatment stenosis. Patients with at least 1 year clinical radiographic follow-up after were included in study. A total 102 met criterion placed CEA group (n = 59) or CAS 43) according their treatment. percentage change BP decrement number a normotensive evaluated...
Background Despite increasing usage of endovascular treatments for intracranial aneurysms, few research studies have been conducted on the incidence unruptured aneurysm (UA) and subarachnoid hemorrhage (SAH), could not show a decrease in SAH. Moreover, socioeconomic disparities with respect to diagnosis treatment UA SAH is lacking. Method Trends incidences newly detected trends modalities used were assessed from 2005 2015 using nationwide database Korean National Health Insurance Service...
Purpose: Clinical outcomes and radiologic results after cervical arthroplasty have been reported in many articles, yet relatively few studies conducted severe degenerative disc disease.Materials Methods: Sixty patients who underwent (Mobi-C ® ) between April 2006 November 2011 with a minimum follow-up of 18 months were enrolled this study.Patients divided into two groups according to Pfirrmann classification on preoperative MR images: group A (Pfirrmann grade III, n=38) B grades IV or V,...
Objective : This study is to investigate time course of symptom disappearance in patients whose spasm relieved completely after microvascular decompression (MVD).Methods Of 115 with hemifacial (HFS) who underwent MVD from April 2003 December 2006, 89 had no facial paralysis operation and showed at last follow-up more than 1.5 years were selected.Symptom was classified into type 1 (symptom right operation), 2 (delayed disappearance) 3 (unusual disappearance).Type 2a (with postoperative silent...
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Hemifacial spasm (HFS) is a clinical syndrome characterized by unilateral facial nerve dysfunction. The usual cause involves vascular compression of the seventh cranial nerve, but an artery passing through very unusual. A 20-year-old man presented with left that had persisted for 4 years. Compression root exit zone anterior inferior cerebellar (AICA) was revealed on magnetic resonance angiography. During microvascular decompression surgery, penetration distal portion AICA observed. At...
IntroductionIntracranial pressure (ICP) control is the main goal in managing traumatic brain injury (TBI).In addition to direct injury, secondary insult due post-traumatic in-crease ICP or decrease cerebral perfusion well recognized as a cause of increased mortality and morbidity. 4,15,18,22,23,27)Although debates concerning its effectiveness improving patient outcomes are ongoing, decompressive craniectomy (DC) widely performed throughout world manage TBI. 38)Although DC has been shown ICP,...
Abstract The rat organic anion transporter 3 (rOAT3) has recently been identified as the third isoform of OAT family. mechanisms that regulate rOAT3's functions remain to be elucidated. rOAT3 contributes for moving a number negatively charged compounds between cells and their extracellular milieu. Caveolin (Cav) also plays role membrane transporter. To address relationship these two proteins, we investigated protein‐protein interaction Cav‐1. mRNA protein expression were observed in kidney,...
We present a case of subdural osteoma. A 29-year-old female presented with 3-year history headaches. Computed tomography scan revealed homogeneous high-density lesion isolated from the inner table frontal bone (a lucent dural line) in right convexity. Magnetic resonance imaging an extra-axial broad base without tail sign and punctate enhancement pattern characteristic abundant adipose tissue. Upon surgical excision, we found hard bony mass clearly demarcated dura. The displayed...
Plant endophyte and epiphyte communities cooperatively interact with their host plants play crucial roles in sustaining plant fitness. In Korea, a variety of studies have been conducted to elucidate the reasons for declining population endangered Korean fir (Abies koreana), but relationship between microbiota healthy condition trees remains unclear. Here, we bacterial 16S rRNA gene fungal ITS sequence analyses dissect composition endophytic epiphytic both live dead located same Mt. Jiri...