A5010940887- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Sleep and Wakefulness Research
- Neural dynamics and brain function
- Neonatal and fetal brain pathology
- Cerebrospinal fluid and hydrocephalus
- Functional Brain Connectivity Studies
University of Oulu
2023-2025
Oulu University Hospital
2023
During sleep, there is an increase in the brain cerebrospinal fluid (CSF) solute convection driven by physiological pulsations. Although main drivers of CSF flow, namely cardiac, respiratory, and vasomotor pulsations, become more powerful during relatively little information regarding their effects on flow velocity across human sleep. Here, we used functional magnetic resonance encephalography (MREG) to measure non-invasively changes water sleep tracking propagating ultrafast signal induced...
Sleep increases brain fluid transport and the power of pulsations driving fluids. We investigated how sleep deprivation or electrophysiologically different stages non-rapid-eye-movement (NREM) affect human pulsations.Fast functional magnetic resonance imaging (fMRI) was performed in healthy subjects (n = 23) with synchronous electroencephalography (EEG), that used to verify arousal states (awake, N1 N2 sleep). Cardiorespiratory rates were verified physiological monitoring. Spectral analysis...
Abstract Respiratory brain pulsations pertaining to intra-axial hydrodynamic solute transport are markedly altered in focal epilepsy. We used optical flow analysis of ultra-fast functional magnetic resonance imaging (fMRI) data investigate the velocity characteristics respiratory impulse propagation patients with epilepsy treated antiseizure medication (ASM) (medicated epilepsy; ME, n = 23), drug-naïve at least one seizure (DN, 19) and matched healthy control subjects (HC, 75). detected two...