A5075952346- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Epilepsy research and treatment
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Neuroscience and Music Perception
- Visual perception and processing mechanisms
- Face Recognition and Perception
- Advanced Neuroimaging Techniques and Applications
- Neonatal and fetal brain pathology
- Multiple Sclerosis Research Studies
- Atomic and Subatomic Physics Research
- Pharmacological Effects and Toxicity Studies
- Peripheral Neuropathies and Disorders
- Systemic Sclerosis and Related Diseases
- Interconnection Networks and Systems
University Hospital of Zurich
2021-2025
University of Zurich
2023-2025
Senckenberg Centre for Human Evolution and Palaeoenvironment
2015-2022
Bernstein Center for Computational Neuroscience Tübingen
2015-2022
Hertie Institute for Clinical Brain Research
2014-2022
University of Tübingen
2015-2022
University of Trento
2021
University of Bern
2021
Universitätsklinikum Tübingen
2015
Importance Acute symptomatic seizures occurring within 7 days after ischemic stroke may be associated with an increased mortality and risk of epilepsy. It is unknown whether the type acute seizure influences this risk. Objective To compare epilepsy following different types seizures. Design, Setting, Participants This cohort study analyzed data acquired from 2002 to 2019 9 tertiary referral centers. The derivation included adults cohorts 2 case-control studies neuroimaging-confirmed without...
Idiopathic/genetic generalized epilepsy (IGE/GGE) is characterized by seizures, which start and rapidly engage widely distributed networks, result in symptoms such as absences, myoclonic primary tonic-clonic seizures. Although routine magnetic resonance imaging apparently normal, many studies have reported structural alterations IGE/GGE patients using diffusion tensor voxel-based morphometry. Changes also been functional networks during spike wave discharges. However, network function the...
To assess the impact of colored noise on statistics in event-related functional MRI (fMRI) (visual stimulation using checkerboards) acquired by simultaneous multislice imaging enabling repetition times (TRs) between 2.64 to 0.26 s.T-values within visual cortex obtained with analysis tools that assume a first-order autoregressive plus white process (AR(1)+w) fixed AR coefficient versus higher-order models spatially varying coefficients were compared. In addition, dependency T-values...
The human brain is known to contain several functional networks that interact dynamically. Therefore, it desirable analyze the temporal features of these by dynamic connectivity (dFC). A sliding window approach was used in an event-related fMRI (visual stimulation using checkerboards) assess impact repetition time (TR) and size on BOLD dFC. In addition, we also examined spatial distribution dFC tested feasibility this for analysis interictal epileptiforme discharges. 15 healthy controls...
Conscious perception of the emotional valence faces has been proposed to involve top-down and bottom-up information processing. Yet, underlying neuronal mechanisms these two processes implementation their cooperation is still unclear. According global workspace model, higher level cognitive processing visual stimuli relies on both Using masking in a backward paradigm with delays at perceptual threshold, which can only partly be detected, suggests that differs between correctly incorrectly...
<h3>Objective</h3> To assess whether neuronal signals in patients with genetic generalized epilepsy (GGE) are heritable, we examined magnetoencephalography resting-state recordings and their healthy siblings. <h3>Methods</h3> In a prospective, cross-sectional design, investigated source-reconstructed power functional connectivity patients, siblings, controls. We analyzed 5 minutes of cleaned awake data without epileptiform discharges 6 frequency bands (1–40 Hz). further calculated intraclass...
Abstract Objective Genetic generalized epilepsy (GGE) is characterized by aberrant neuronal dynamics and subtle structural alterations. We evaluated whether a combination of magnetic electrical signals cortical thickness would provide complementary information about network pathology in GGE. also investigated these imaging phenotypes were present healthy siblings the patients to test for genetic influence. Methods In this cross‐sectional study, we analyzed 5 min resting state data acquired...
Genetic generalized epilepsies (GGEs) are characterized by spike-wave discharges (GSWDs) in electroencephalography (EEG) recordings without underlying structural brain lesions. The origin of the epileptic activity remains unclear, although several studies have reported involvement thalamus and default mode network (DMN). aim current study was to investigate networks involved generation temporal evolution GSWDs elucidate propagation activity.We examined 12 patients with GGE using...
Abstract Conscious perception of emotional valence faces has been proposed to involve top-down and bottom-up information processing. Yet, the underlying neuronal mechanisms these two processes implementation their cooperation is still unclear. We hypothesized that networks activated during interaction are key substrates responsible for perception. assessed participation neural involved in conscious stimuli near perceptual threshold using a visual-backward-masking paradigm 12 healthy...
Abstract Despite several studies investigating the relationship between blood-oxygen-level-dependent functional MRI (BOLD-fMRI) and neuroelectric activity, our understanding is rather incomplete. For instance, canonical hemodynamic response function (HRF) commonly used, regardless of brain region, frequency electric activity networks. We studied this BOLD-fMRI electroencephalography (EEG) signal human in detail using simultaneous fMRI EEG healthy awake subjects at rest. Signals from sensors...