A5078842723- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Dietary Effects on Health
- Physical Activity and Health
- Obesity and Health Practices
- Nutritional Studies and Diet
- Circadian rhythm and melatonin
- Sleep and related disorders
- Health and Lifestyle Studies
- Nutrition, Genetics, and Disease
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Gut microbiota and health
- Genetic and Kidney Cyst Diseases
- Epigenetics and DNA Methylation
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Renal and related cancers
- COVID-19 and Mental Health
- Gestational Diabetes Research and Management
- Impact of Light on Environment and Health
- Pharmacology and Obesity Treatment
- Bariatric Surgery and Outcomes
- Behavioral Health and Interventions
University of Colorado Anschutz Medical Campus
2016-2025
University of Colorado Denver
2008-2023
University of Colorado System
2020
Colorado School of Public Health
2016
University of Denver
2009
University of Colorado Health
2006-2008
To evaluate the safety and tolerability of alternate-day fasting (ADF) to compare changes in weight, body composition, lipids, insulin sensitivity index (Si) with those produced by a standard weight loss diet, moderate daily caloric restriction (CR).Adults obesity (BMI ≥30 kg/m(2) , age 18-55) were randomized either zero-calorie ADF (n = 14) or CR (-400 kcal/day, n 12) for 8 weeks. Outcomes measured at end 8-week intervention after 24 weeks unsupervised follow-up.No adverse effects...
Objective: The National Weight Control Registry (NWCR) was established in 1993 to examine the characteristics of those who are successful at weight loss: individuals maintaining a 13.6‐kg loss for >1 year. size registry has increased substantially since early descriptions this group decade ago. purpose study describe detail weekly physical activity habits NWCR members, relationship between amount and demographic characteristics, determine if changes parameters have occurred over time....
This trial aimed to evaluate the acceptability and efficacy of early time-restricted eating plus daily caloric restriction (E-TRE+DCR) compared with DCR alone within a behavioral weight-loss intervention.Participants (n = 81, 69 women, mean [SD] age: 38.0 [7.8] years, BMI: 34.1 [5.7] kg/m2 ) were randomized E-TRE (10-hour window starting 3 hours waking) or (~35% DCR) for 39 weeks. The primary outcome was body weight (measured digital scale) at week 12. Secondary outcomes measured 12 included...
The National Weight Control Registry (NWCR) was established in 1993 to examine characteristics of successful weight-loss maintainers. This group consistently self-reports high levels physical activity. aims this study were obtain objective assessments activity NWCR subjects and compare both normal-weight overweight controls. Individuals from the (n = 26) compared a never obese control matched group's current BMI 30), an self-reported pre-weight-loss 34). Objective assessment obtained for...
The National Weight Control Registry (NWCR) is the largest ongoing study of individuals successful at maintaining weight loss; registry enrolls a loss least 13.6 kg (30 lb) for minimum 1 year. current report uses multivariate latent class cluster analysis to identify unique clusters within NWCR that have distinct experiences, strategies, and attitudes with respect maintenance. considers health history, control behaviors effort satisfaction weight, psychological demographic characteristics....
Objective The objective of this study was to compare physical activity energy expenditure (PAEE) and total daily (TDEE) in successful weight loss maintainers (WLM) with normal controls (NC) overweight/obesity (OC). Methods Participants were recruited three groups: WLM ( n = 25, BMI 24.1 ± 2.3 kg/m 2 ; maintaining ≥ 13.6‐kg for 1 year), NC 27, 23.0 2.0 similar current WLM), OC 28, 34.3 4.8 pre–weight WLM). TDEE measured using the doubly labeled water method. Resting (REE) indirect...
Background: The National Weight Control Registry (NWCR) was established to examine characteristics of successful weight loss maintainers. This study compares the diet and behavioral regain trajectories NWCR members with differing physical activity (PA) levels at baseline. Methods: Participants (n = 3591) were divided into 4 self-reported PA registry entry (< 1000, 1000 < 2250, 2250 3500, ≥ 3500 kcals/week). We compared energy intake (EI), macronutrient composition, eating behaviors...
The objective of this study was to compare patterns objectively measured moderate-to-vigorous physical activity (MVPA, ≥ 3.00 metabolic equivalents [METs]), light-intensity (LPA, 1.50-2.99 METs), and sedentary behavior (SB, < 1.50 METs) in successful weight loss maintainers (WLMs), normal controls (NC), with overweight/obesity (OC).Participants (18-65 y) were recruited three groups: WLM (maintaining 13.6-kg for 1 year, n = 30), NC (BMI matched current BMI WLM, 33), OC pre-weight 27). All...
Accumulating evidence suggests that later timing of energy intake (EI) is associated with increased risk obesity. In this study, 83 individuals overweight and obesity underwent assessment a 7-day period data collection, including measures body weight composition (DXA) 24-h EI (photographic food records), sleep (actigraphy), physical activity (PA, monitors) for 7 days. Relationships between mass index (BMI) percent fat meal timing, sleep, PA were examined. For every 1 h start eating, there...
Altered gut microbiota has been linked to obesity and may influence weight loss. We are conducting an ongoing loss trial, comparing daily caloric restriction (DCR) intermittent fasting (IMF) in adults who overweight or obese. report here ancillary study of the selected obesity-related parameters at baseline after first three months interventions. During this time, participants experienced significant improvements clinical health measures, along with altered composition diversity fecal...
Long-term (≥12 months) randomized trials evaluating the efficacy of intermittent fasting (IMF) as a dietary weight loss strategy are limited. Furthermore, no studies have compared IMF versus daily caloric restriction (DCR) when both interventions provided in context guidelines-based behavioral program.
Summary Obesity rates are increasing in most countries throughout the world. The reasons for increase complex and involve biological, behavioural environmental factors. We have unintentionally created environments that encourage over‐eating discourage physical activity. Despite recognition of seriousness obesity to public health, no interventions been effective reducing on a population basis. Reversing within populations will require addressing both individual behaviour obesogenic...
The purpose of this study was to evaluate the feasibility and acceptability randomizing adults with overweight obesity (BMI 25-40 kg/m
Objective The aim of this cross-sectional study was to evaluate prevalence and strategies behind low/no calorie sweetened beverage (LNCSB) consumption in successful weight loss maintainers. Methods An online survey administered 434 members the National Weight Control Registry (NWCR, individuals who have lost ≥13.6 kg maintained for > 1 year). Results While few participants (10%) consume sugar-sweetened beverages on a regular basis, 53% regularly LNCSB. top five reasons choosing LNCSB were...
Daytime light exposure has been reported to impact or have no influence on energy metabolism in humans. Further, whether inter-individual differences wake, sleep, 24 h expenditure, and RQ during circadian entrainment misalignment are stable across repeated assessments is largely unknown. We present data from two studies: Study 1 of 15 participants (7 females) exposed three conditions: continuous typical room ~100 lx warm white light, ~750 alternating hourly blue-enriched separate days a...
Abstract Objective The COVID‐19 pandemic has resulted in significant changes to daily life and many health‐related behaviors. objective of this study was examine how the stay‐at‐home/safer‐at‐home mandates issued Colorado (March 2020–May 2020) impacted lifestyle behaviors mental health among individuals with overweight or obesity participating two separate behavioral weight loss trials ( n = 82). Methods Questionnaires were used collect qualitative quantitative data on challenges presented...
Abstract Objective Weight loss of ≥10% improves glucose control and may remit type 2 diabetes (T2D). High‐protein (HP) diets are commonly used for weight loss, but whether protein sources, especially red meat, impact loss‐induced T2D management is unknown. This trial compared an HP diet including beef a normal‐protein (NP) without meat body composition changes, in individuals with T2D. Methods A total 106 adults (80 female) consumed (40% protein) ≥4 weekly servings lean or NP (21% excluding...
Abstract Background The standard of care for treating overweight and obesity is daily caloric restriction (DCR). While this approach produces modest weight loss, adherence to DCR declines over time regain common. Intermittent fasting (IMF) an alternative dietary strategy reducing energy intake (EI) that involves >60% on 2–3 days per week, or alternate days, with habitual fed days. numerous studies have evaluated IMF as a loss strategy, there are several limitations including lack...