- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Obesity and Health Practices
- Eating Disorders and Behaviors
- Nutritional Studies and Diet
- Physical Activity and Health
- Health and Lifestyle Studies
- Pharmacology and Obesity Treatment
- Bariatric Surgery and Outcomes
- Muscle metabolism and nutrition
- Nutrition and Health in Aging
- Diabetes Treatment and Management
- Diet, Metabolism, and Disease
- Regulation of Appetite and Obesity
- Cancer survivorship and care
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Behavioral Health and Interventions
- Cancer Risks and Factors
- Adipose Tissue and Metabolism
- Urban Transport and Accessibility
- Metabolism, Diabetes, and Cancer
- Nutrition, Genetics, and Disease
University of Alabama at Birmingham
2020-2025
University of Colorado Anschutz Medical Campus
2014-2023
University of Colorado Denver
2009-2022
University of Pittsburgh
1999-2022
Providence College
2020
Novo Nordisk (Finland)
2018
University of California, San Diego
2015
University of California, Los Angeles
2007-2015
Temple University
2010-2013
Pennington Biomedical Research Center
2013
The obesity epidemic shows no signs of abating. There is an urgent need to push back against the environmental forces that are producing gradual weight gain in population. Using data from national surveys, we estimate affecting energy balance by 100 kilocalories per day (by a combination reductions intake and increases physical activity) could prevent most This can be achieved small changes behavior, such as 15 minutes walking or eating few less bites at each meal. Having specific behavioral...
Despite the popularity of low-carbohydrate, high-protein, high-fat (Atkins) diet, no randomized, controlled trials have evaluated its efficacy.
Abstract Objective: To examine the effects of naltrexone/bupropion (NB) combination therapy on weight and weight‐related risk factors in overweight obese participants. Design Methods: CONTRAVE Obesity Research‐II (COR‐II) was a double‐blind, placebo‐controlled study 1,496 (BMI 30‐45 kg/m 2 ) or (27‐45 with dyslipidemia and/or hypertension) participants randomized 2:1 to combined naltrexone sustained‐release (SR) (32 mg/day) plus bupropion SR (360 (NB32) placebo for up 56 weeks. The...
Given the risk of obesity and diabetes in U.S., clear benefit exercise disease prevention management, this study aimed to determine prevalence physical activity among adults with at for diabetes.The Medical Expenditure Panel Survey is a nationally representative survey U.S. population. In 2003 survey, 23,283 responded when asked about whether they were physically active (moderate or vigorous activity, > =30 min, three times per week). Information on sociodemographic characteristics health...
Obesity and physical inactivity are established risk factors for type 2 diabetes cardiovascular comorbidities. Whether adiposity or fitness level is more important to health controversial. The objective of this research determine the relative associations activity BMI with prevalence diabetes-related comorbidities in U.S.The Medical Expenditure Panel Survey (MEPS) a nationally representative survey U.S. population. From 2000 2002, detailed information on sociodemographic characteristics...
U.S. adults may have lower levels of ambulatory physical activity compared with living in other countries.The purpose this study was to provide descriptive, epidemiological data on the average number steps per day estimated be taken by and identify predictors pedometer-measured basis demographic characteristics self-reported behavioral characteristics.The America On Move conducted 2003. Individuals (N = 2522) aged 13 yr older consented fill out a survey, including 1921 18 older. Valid...
Obesity increases risk for all-cause and breast cancer mortality comorbidities in women who have been diagnosed treated cancer. The Exercise Nutrition to Enhance Recovery Good Health You (ENERGY) study is the largest weight loss intervention trial among survivors of date.In this multicenter trial, 692 overweight/obese were, on average, 2 years since primary treatment early-stage were randomly assigned either a group-based behavioral intervention, supplemented with telephone counseling...
The objective of this study was to investigate the efficacy and safety Epitomee capsule versus placebo as an adjunct high-intensity lifestyle intervention in participants with overweight or obesity. Randomized Evaluation Efficacy Safety Capsule Trial (RESET) a prospective, double-blind, placebo-controlled pivotal trial adults baseline BMI 27.0 40.0 kg/m2. co-primary endpoints at week 24 were percentage change from body weight for groups proportion Epitomee-treated patients achieving ≥5% loss...
Abstract Objective: To examine breakfast consumption in subjects maintaining a weight loss the National Weight Control Registry (NWCR). Research Methods and Procedures: A cross‐sectional study which 2959 NWCR completed demographic history questionnaires as well questions about their current consumption. All had maintained of at least 13.6 kg (30 lb) for 1 year; on average these lost 32 kept it off 6 years. Results: large proportion (2313 or 78%) reported regularly eating every day week. Only...
Despite significant efforts, obesity continues to be a major public health problem, and there are surprisingly few effective strategies for its prevention treatment. We now realize that healthy diet activity patterns difficult maintain in the current physical environment. Recently, it was suggested social environment also contributes obesity. Therefore, using network-based interaction models, we simulate how spreads along networks predict effectiveness of large-scale weight management...
OBJECTIVES. The intent of this study was to evaluate whether small changes in diet and physical activity, as promoted by the America on Move initiative, could prevent excessive weight gain overweight children. METHODS. In family-intervention study, small-changes approach for weight-gain prevention evaluated families with at least 1 child (7–14 years old) who or risk overweight. These children were primary target intervention, parents secondary target. Families randomly assigned either group...
The consumption of pomegranate juice (PJ), a rich source antioxidant polyphenols, has grown tremendously due to its reported health benefits. Pomegranate extracts, which incorporate the major antioxidants found in pomegranates, namely, ellagitannins, have been developed as botanical dietary supplements provide an alternative convenient form for consuming bioactive polyphenols PJ. Despite commercial availability extract supplements, there no studies evaluating their safety human subjects. A...
Objective: The National Weight Control Registry (NWCR) was established in 1993 to examine the characteristics of those who are successful at weight loss: individuals maintaining a 13.6‐kg loss for >1 year. size registry has increased substantially since early descriptions this group decade ago. purpose study describe detail weekly physical activity habits NWCR members, relationship between amount and demographic characteristics, determine if changes parameters have occurred over time....
The study objective was to evaluate the effect of prescribing a low-carbohydrate diet (LCD) and low-fat (LFD) on food cravings, preferences, appetite. Obese adults were randomly assigned LCD (n = 134) or LFD 136) for 2 years. Cravings specific types foods (sweets, high-fats, fast-food fats, carbohydrates/starches); preferences high-sugar, high-carbohydrate, low-carbohydrate/high-protein foods; appetite measured during trial evaluated this secondary analysis data. Differences between change...
Objective To compare the efficacy of non-nutritive sweetened beverages (NNS) or water for weight loss during a 12-week behavioral treatment program. Methods An equivalence trial design with NNS as main factor in prospective randomized among 303 men and women was employed. All participants participated The results phase (12 weeks) an ongoing (1 year) that is also evaluating effects these two treatments on maintenance were reported. Results not equivalent beverage group losing significantly...
Objective To evaluate the effects of water versus beverages sweetened with non‐nutritive sweeteners (NNS) on body weight in subjects enrolled a year‐long behavioral loss treatment program. Methods The study used randomized equivalence design NNS or as main factor trial among 303 weight‐stable people overweight and obesity. All participants participated program plus assignment to consume 24 ounces (710 ml) daily for 1 year. Results treatments were non‐equivalent, showing greater at end At...