- Health Systems, Economic Evaluations, Quality of Life
- Health Policy Implementation Science
- Schizophrenia research and treatment
- Pharmaceutical studies and practices
- Mobile Health and mHealth Applications
- Pharmaceutical Practices and Patient Outcomes
- Healthcare Policy and Management
- Diabetes Management and Education
- Diet and metabolism studies
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical Economics and Policy
- Health and Medical Research Impacts
- Public Health Policies and Education
- Meta-analysis and systematic reviews
- Family and Disability Support Research
- Health Sciences Research and Education
- Diabetes Management and Research
- Digital Mental Health Interventions
- Ethics in Clinical Research
- Childhood Cancer Survivors' Quality of Life
- Diabetes Treatment and Management
- Infant Development and Preterm Care
- Medication Adherence and Compliance
- Pharmaceutical industry and healthcare
- Biomedical and Engineering Education
Loyola University Chicago
2020-2024
University of Chicago
2022-2023
University of Colorado Anschutz Medical Campus
2013-2022
Colorado School of Public Health
2013-2022
Outcomes Research Consortium
2019-2022
Chicago Department of Public Health
2022
United States Food and Drug Administration
2020-2021
University of Pittsburgh
2021
University of Colorado Denver
2008-2018
Children's Hospital Colorado
2010-2016
Given the risk of obesity and diabetes in U.S., clear benefit exercise disease prevention management, this study aimed to determine prevalence physical activity among adults with at for diabetes.The Medical Expenditure Panel Survey is a nationally representative survey U.S. population. In 2003 survey, 23,283 responded when asked about whether they were physically active (moderate or vigorous activity, > =30 min, three times per week). Information on sociodemographic characteristics health...
Background Although growing concern has been expressed about premature medical mortality in persons with mental illness, limited data are available quantifying the extent and correlates of this problem using population-based, nationally representative samples. Methods The study used from 1989 National Health Interview Survey health supplement, through 2006 linked Death Index (80,850 participants, 16,435 deaths). Multivariable models adjusting for demographic factors assessed increased hazard...
Obesity and physical inactivity are established risk factors for type 2 diabetes cardiovascular comorbidities. Whether adiposity or fitness level is more important to health controversial. The objective of this research determine the relative associations activity BMI with prevalence diabetes-related comorbidities in U.S.The Medical Expenditure Panel Survey (MEPS) a nationally representative survey U.S. population. From 2000 2002, detailed information on sociodemographic characteristics...
Objective: In October 2003, the U.S. Food and Drug Administration (FDA) issued a public health advisory about risk of suicidality in pediatric patients taking selective serotonin reuptake inhibitors (SSRIs) for depression. This study used data from large national cohort to examine patterns diagnosis depression, prescription antidepressants, pharmacological alternatives use psychosocial care before after FDA was issued. Method: A with newly diagnosed episodes depression created integrated...
In 2003, the Food and Drug Administration (FDA) required a warning on diabetes risk for second-generation antipsychotic (SGA) drugs. The American Diabetes Association (ADA) Psychiatric (APA) recommended glucose lipid testing all patients starting to receive SGA drugs.To characterize associations between combined warnings recommendations baseline metabolic drug selection.Interrupted time-series analysis.California, Missouri, Oregon. Patients A total of 109 451 individuals receiving Medicaid...
OBJECTIVE Several second-generation antipsychotic (SGA) drugs have been associated with weight gain, hyperglycemia, and dyslipidemia. We evaluated whether glucose lipid testing increased after the American Diabetes Association (ADA) consensus statement recommending metabolic monitoring for SGA-treated patients. RESEARCH DESIGN AND METHODS Laboratory claims serum were identified an incident cohort of 18,876 adults initiating SGA in a U.S. commercial health plan (2001–2006) control group...
Pediatric surgical procedures are being performed in a variety of hospitals with large differences volume. We examined the frequency and inpatient pediatric United States by hospital type geographic region using nationally representative sample.The 2009 Kids' Inpatient Database for patients <18 years old was used to calculate frequencies International Classification Diseases, Ninth Revision, Clinical Modification, (ICD-9-CM) codes. stratified analysis (free-standing children's hospital, unit...
<h3>Objectives</h3> To estimate metabolic screening rates, predictors of screening, and incidence disturbances in children initiating second-generation antipsychotic (SGA) drug treatment. <h3>Design</h3> A retrospective, new-user cohort study (between July 1, 2004, June 30, 2006) using Medicaid claims data. <h3>Settings</h3> California, Missouri, Oregon. <h3>Patients</h3> total 5370 (aged 6-17 years) without diabetes mellitus taking SGA drugs 15 000 albuterol (control) but no drugs....
Abstract The Accrual to Clinical Trials (ACT) network is a federated of sites from the National and Translational Science Award (CTSA) Consortium that has been created significantly increase participant accrual multi-site clinical trials. ACT represents an unprecedented collaboration among diverse CTSA sites. governance regulatory frameworks common data model harmonize electronic health record (EHR) data, deployed set Informatics for Integrating Biology Bedside (i2b2) repositories are linked...
Objective: In 2003, the U.S. Food and Drug Administration (FDA) issued a public health advisory about risk of suicidality in pediatric patients taking selective serotonin reuptake inhibitors (SSRIs) for depression, 2005, agency mandated black box warning medication guide indicating that adult may be at risk. The authors examine effects this policy on treatment depression community. Method: An cohort with newly diagnosed episodes was created from large national integrated claims database...
Article AbstractObjective: Increased risk of diabetes and dyslipidemia is associated with major mental illness antipsychotic drug use. This study aimed to determine the prevalence serum glucose lipid monitoring in public health clients initiating second-generation (SGA) drugs. Method: retrospective cohort using Medicaid claims data from California, Oregon, Tennessee, Utah evaluated 55,436 enrollees a prescription claim for an SGA between January 1, 1998, December 31, 2003. Serum testing were...
Objective: The Food and Drug Administration (FDA) issued a public health advisory in October 2003 on the risk of suicide pediatric patients taking antidepressants advised maintaining "close supervision" such patients. In this study, authors compared trends frequency provider contacts for with depression before after was issued. Method: Retrospective cohorts children (N=27,370) adults (N=193,151) new episodes treated were created from national claims database managed care plans (1998–2005)....
OBJECTIVE—With increased focus on the obesity and diabetes epidemics, clear benefit of exercise in disease prevention management, this study determined lifetime prevalence health professional advice to among individuals with or at risk for diabetes. RESEARCH DESIGN AND METHODS—The Medical Expenditure Panel Survey is a nationally representative survey U.S. population. In 2002 survey, 26,878 adults responded when asked about ever receiving more. Information sociodemographic characteristics...
<h3>Importance</h3> Federal per-child early intervention (EI) appropriations have declined, while accountability for improving children's development and function has increased. It is critical to understand high-value EI services systems. <h3>Objective</h3> To examine service timeliness intensity, the association between intensity outcomes. <h3>Design, Setting, Participants</h3> This secondary data analysis cohort study linked pediatric primary care electronic health records program from...
Abstract Background Early Intervention (EI) is a federally mandated, state-administered system of care for children with developmental delays and disabilities under the age three. Gaps exist in process accessing EI through pediatric primary care, low rates access are well documented disproportionately affect poor minority children. The aims this paper to examine child characteristics associated gaps (1) referral, (2) (3) service use. To our knowledge, first study leverage linked safety net...
The Reporting recommendations Intended for pharmaceutical risk Minimization Evaluation Studies (RIMES) was developed to improve the quality of reporting minimization program evaluations. In light continued inadequacies in study reporting, and high-profile implementation failures, we updated RIMES Checklist incorporate additional concepts from Standards Implementation studies (StaRI). development checklist, RIMES-StaRI Extension (RIMES-SE), entailed developing a protocol drafting an initial...
Fundoplication is a common pediatric surgery, but little data comparing the laparoscopic approach with open have been published.To compare infection rates, complication length of stay, and cost for fundoplication versus among patients to examine trends in utilization fundoplication.We used Pediatric Health Information System database conduct retrospective study children (aged <19 years) admitted between 2005 2008. Descriptive characteristics those undergoing were compared. Multivariate...
Regulators are increasingly mandating the use of pharmaceutical risk-minimization programs for a variety medicinal products. To date, however, evaluations these have shown mixed results and relatively little attention has been directed at diagnosing specific factors contributing to program success or lack thereof. Given growing in many different patient populations, it is imperative understand how best design, deliver, disseminate, assess them. In this paper, we argue that current approaches...
Currently, national training programs do not have the capacity to meet growing demand for dissemination and implementation (D&I) workforce education development. The Colorado Research in Implementation Science Program (CRISP) developed delivered an introductory D&I workshop adapted from extend reach foster a local learning community D&I. To gauge interest assess needs, pre-registration survey was administered. Based on feedback, 1.5-day designed. Day 1 introduced frameworks, strategies,...
Abstract Objective To evaluate the relationship between direct cognitive assessment introduced with Medicare Annual Wellness Visit (AWV) and new diagnoses of dementia, to determine if effects vary by race. Data Sources Limited Set 5% sample claims 2003‐2014 HRSA Area Health Resources Files. Study Design Instrumental Variable approach estimating AWV utilization dementia using county‐level Welcome rates as an instrument. Collection/Extraction Methods Three hundred twenty‐four thousand three...
Background: We performed a retrospective cohort study of 7637 spinal fusion surgical cases from 2004 to 2006 at 38 children’s hospitals participating in the Pediatric Health Information System database evaluate variability in-hospital outcomes by patient factors and between facilities children who underwent surgery. Methods: Outcomes were stratified whether did or not have neurological impairment. Multilevel multivariate logistic regression models used determine hospital associated with...
Pharmaceutical risk minimization programs involve interventions designed to support safe and appropriate use of medicines. Currently, information regarding the evaluation these is not publicly reported in a standardized transparent manner. To address this gap, we developed piloted quality reporting checklist entitled Reporting recommendations Intended for pharmaceutical Minimization Evaluation Studies (RIMES). Checklist development was guided by three sources: (1) theoretical framework...