A5033803578- Health Systems, Economic Evaluations, Quality of Life
- Health Policy Implementation Science
- Primary Care and Health Outcomes
- Mental Health and Patient Involvement
- Healthcare Policy and Management
- Clinical practice guidelines implementation
- Trauma and Emergency Care Studies
- Pharmaceutical industry and healthcare
- Healthcare cost, quality, practices
- Acute Myocardial Infarction Research
- Health and Medical Research Impacts
- Health Sciences Research and Education
- Ethics in Clinical Research
- Coronary Interventions and Diagnostics
- Emergency and Acute Care Studies
- Obstructive Sleep Apnea Research
- Evaluation and Performance Assessment
- Occupational Health and Performance
- Statistical Methods in Clinical Trials
- Geriatric Care and Nursing Homes
- Injury Epidemiology and Prevention
- Meta-analysis and systematic reviews
- Complement system in diseases
- Patient Satisfaction in Healthcare
- Medical Education and Admissions
RAND Corporation
2016-2025
Tufts University
2014-2025
Southern California Clinical and Translational Science Institute
2010-2024
Tufts Medical Center
2007-2021
Agency for Healthcare Research and Quality
2017
Boston University
2017
Northwestern University
2017
University of Alabama at Birmingham
2017
Global Healthy Living Foundation
2017
Carolina Veterinary Specialists
2015
Abstract Background Stakeholder engagement has become widely accepted as a necessary component of guideline development and implementation. While frameworks for developing guidelines express the need those potentially affected by recommendations to be involved in their development, there is lack consensus on how this should done practice. Further, guidance equitably meaningfully engage multiple stakeholders. We aim develop meaningful equitable stakeholders Methods This will multi-stage...
SUMMARY We assessed how much, if anything, people would pay for a laboratory test that predicted their future disease status. A questionnaire was administered via an internet‐based survey to random sample of adult US respondents. Each respondent answered questions about two different scenarios, each which specified: one four randomly selected diseases (Alzheimer's, arthritis, breast cancer, or prostate cancer); ex ante risk developing the (randomly designated 10 25%); and accuracy perfect...
Abstract Background Given the colonial connotations of term “stakeholder”, its continued use may be perceived as disrespectful to Indigenous Peoples. While several groups have introduced alternative terms, each has own limitations. The objective this article is introduce “interest‐holders” an “stakeholders” and describe discussions underpinning adoption new by MuSE Consortium. Methods Consortium international network over 160 individuals with interest expertise in different aspects relevant...
The delivery of burn care is a resource-intensive endeavor that requires specialized personnel and equipment. optimal geographic distribution centers has long been debated; however, the current relative to area population unknown.
In 2001, 1176 US hospitals were capable of performing primary percutaneous coronary intervention (PCI), and 79% the population lived within 60-minute ground transport these hospitals. We compared estimates with data from 2006 to explore how hospital PCI capability access have changed over time.We estimated proportion 18 years age or older, living in a drive PCI-capable hospital, we our estimate previously published report on 2001 data. Over 5-year period, number grew 1695 hospitals, relative...
Established in 2015, the Multi-Stakeholder Engagement (MuSE) Consortium is an international network of over 120 individuals interested stakeholder engagement research and guidelines. The MuSE group developing guidance for development health healthcare guideline development. this has included multiple meetings with stakeholders, including patients, payers/purchasers services, peer review editors, policymakers, program managers, providers, principal investigators, product makers, public,...
PURPOSE: A notable increase in-hospital admissions for Clostridium difficile colitis has occurred in the United States. In this paper we evaluate changes epidemiology of a subset hospitalized patients with inflammatory bowel diseases. METHODS: retrospective cohort analysis was conducted all disease Nationwide Inpatient Sample, 20 percent stratified random sample national hospital discharge abstracts from 1993 through 2003. Using standard diagnostic codes, identified yearly difficile, other...
Primary percutaneous coronary intervention (PCI) is more effective on average than fibrinolytic therapy in the treatment of ST-segment-elevation myocardial infarction. Yet, most US hospitals are not equipped for PCI, and still widely used. This study evaluated comparative effectiveness infarction regionalization strategies to increase use PCI against standard emergency transport care.We estimated incremental costs quality-adjusted life expectancies 2000 patients with who received or...
Background— Evidence suggests that recent and projected future investments in percutaneous coronary intervention (PCI) programs at US hospitals fail to increase access timely reperfusion for patients with ST-segment elevation myocardial infarction. Methods Results— We set out estimate the annual number costs of new PCI from 2004 2008 identify characteristics hospitals, neighborhoods, states where have been introduced. estimated a discrete-time hazard model measure influence these on decision...
Background— In patients with a major cardiac event, the first priority is to minimize time treatment. For many patients, contact health system through emergency medical services (EMS). We set out identify patient-level and neighborhood-level factors that were associated elapsed in EMS. Methods Results— A retrospective cohort study was conducted 10 municipalities Dallas County, Tex, from January 1 December 31, 2004. The data included 5887 suspected cardiac-related symptoms. region served by...
Abstract Background Health research teams increasingly partner with stakeholders to produce that is relevant, accessible, and widely used. Previous work has covered stakeholder group identification. Objective We aimed develop factors for health consider during identification invitation of individual representatives in a multi-stakeholder partnership, the aim forming equitable informed teams. Design Consensus development. Participants involved 16 from international Multi-Stakeholder...
An important challenge in comparative effectiveness research is the lack of infrastructure to support pragmatic clinical trials, which compare interventions usual practice settings and subjects. These trials present challenges that differ from those classical efficacy are conducted under ideal circumstances, patients selected for their suitability, with highly controlled protocols. In 2012, we launched a 1-year learning network identify high-priority deploy through NIH Clinical Translational...
Introduction Stakeholder engagement can play an important role in increasing public trust and the understanding of scientific research its impact. Frameworks for stakeholder identification exist, but these frameworks may not apply well to basic science early stage translational research. Methods Four Clinical Translational Science Award (CTSA) hubs led six focus groups two semi-structured interviews using a discussion guide learn from researchers about their work. The 24 participants...
Although the US FDA encourages manufacturers of medical devices to submit real-world evidence (RWE) support regulatory decisions, ability data (RWD) generate suitable for decision making remains unclear. The 2017 Medical Device User Fee Amendments (MDUFA IV), authorized National Evaluation System health Technology Coordinating Center (NESTcc) conduct pilot projects, or 'Test-Cases', assess whether current RWD captures information needed answer research questions proposed by industry...
To identify ongoing practices and opportunities for improving national comparative effectiveness research (CER) translation through dissemination implementation (D&I) via NIH-funded Clinical Translational Science Award (CTSA) institutions.Key informant interviews were conducted with 18 CTSA grantees sampled to represent a range of D&I efforts.The institutional representatives endorsed fostering CER nationally the Consortium. However, five themes emerged from as barriers D&I: lack awareness,...
Background Studies of some human prothrombotic diseases suggest that phosphatidylserine‐positive ( PS +) and tissue factor‐positive TF microparticles MP s) might play a role in the pathogenesis thrombosis or serve as biomarkers thrombotic risk. Hypothesis/Objectives To determine if circulating levels + procoagulant activity PCA ) associated with s are increased dogs IMHA . Animals Fifteen primary secondary 17 clinically healthy dogs. Methods Prospective case‐controlled observational study....
Traumatic brain injury (TBI) is considered a signature of modern warfare, though TBIs can also result from training accidents, falls, sports, and motor vehicle accidents. Among service members diagnosed with TBI, the majority cases are mild (mTBIs), known as concussions. Many these receive care through Military Health System, but amount, type, quality they has been largely unknown. A RAND study, first to examine mTBI census patients in assessed number characteristics (including deployment...