A5051529501- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Inflammatory Bowel Disease
- Pelvic floor disorders treatments
- Minimally Invasive Surgical Techniques
- Appendicitis Diagnosis and Management
- Microscopic Colitis
- Colorectal and Anal Carcinomas
- Enhanced Recovery After Surgery
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Surgical Simulation and Training
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Urological Disorders and Treatments
- Abdominal Surgery and Complications
- Stoma care and complications
- Hernia repair and management
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal Tumor Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Surgical site infection prevention
Lahey Medical Center
2014-2024
Lahey Hospital and Medical Center
2015-2024
Fondazione Toscana Gabriele Monasterio
2024
American Society of Colon and Rectal Surgeons
2011-2021
Baylor University Medical Center
2018
University of Missouri
2017
Burlington College
1992-2016
Tufts University
2008-2014
American College of Surgeons
2012
American College of Financial Services
2012
IMPORTANCEEvidence about the efficacy of laparoscopic resection rectal cancer is incomplete, particularly for patients with more advanced-stage disease.OBJECTIVE To determine whether noninferior to open resection, as determined by gross pathologic and histologic evaluation resected proctectomy specimen.DESIGN, SETTING, AND PARTICIPANTS A multicenter, balanced, noninferiority, randomized trial enrolled between October 2008 September 2013.The was conducted credentialed surgeons from 35...
INTRODUCTION: Surgeons have been reluctant to apply laparoscopic techniques Crohn's disease surgery because of concerns with evaluating and excising inflamed tissue using methods Additionally in surgery, not demonstrated clear advantages over conventional ones. METHOD: We conducted a prospective, randomized trial one surgical department comparing vs. 60 patients (25 males), median age 34.4 (range 10-60.1) years, undergoing elective ileocolic resection for refractory disease. Postoperatively,...
To determine the disease-free survival (DFS) and recurrence after treatment of patients with rectal cancer open (OPEN) or laparoscopic (LAP) resection.This randomized clinical trial (ACOSOG [Alliance] Z6051), performed between 2008 2013, compared LAP OPEN resection stage II/III cancer, within 12 cm anal verge (T1-3, N0-2, M0) in who received neoadjuvant chemoradiotherapy. The rectum mesorectum were resected using instruments for dissection (included hybrid hand-assisted laparoscopic) under...
PURPOSE: The purpose of our study was to determine the clinical and CT predictors recurrent disease after a first episode diverticulitis that successfully managed nonoperatively. METHODS: We retrospectively analyzed 954 consecutive patients who presented institution with from 2002 2008. Patients were identified International Classification Diseases, 9th Revision/Current Procedural Terminology codes. excluded if they had subsequent colectomy based on attack (n = 81), or between 2008 not their...
PURPOSE: A laparoscopic approach to restorative proctocolectomy is new and has not been compared recently with the traditional open procedure. By using prospectively gathered data, procedures in mucosal ulcerative colitis familial adenomatous polyposis patients were by a case-matched design. METHODS: Forty patients, composing 20 consecutive cases (13 colitis, 7 polyposis), matched for age, gender, body mass index polyposis) performed during same time period. Mucosal also severity of disease...
Many surgeons consider the ileoanal pouch procedure to be of choice for patients who require surgery ulcerative colitis and familial adenomatous polyposis. To determine long-term results, 460 (mean +/- SD age, 31 9 years) underwent from 1980 through 1991 were prospectively observed by computerized registry. The leading indication operation was (n = 382; 83%). A J-shaped reservoir created in 434 (94%). More than 5 years after ileostomy closure, mean number bowel movements 5.8 2.2, 13% had...
This study was designed to compare short-term outcomes after hand-assisted laparoscopic vs. straight colorectal surgery.Eleven surgeons at five centers participated in a prospective, randomized trial of patients undergoing elective sigmoid/left colectomy and total colectomy. The powered detect 30-minute reduction operative time between groups.There were 47 (33 colectomy, 14 colectomy) 48 15 colectomy). There no differences the patient age, sex, body mass index, previous surgery, diagnosis,...
There are no previous comparative studies of total abdominal colectomy by laparoscopic methods in ulcerative colitis and Crohn's disease patients requiring urgent colectomy. This study aimed to determine the safety efficacy these compared with those undergoing conventional colectomy.Patients for acute were identified a prospective registry. All underwent creation an end ileostomy buried mucous fistula. No patient had fulminant (tachycardia, fever, marked leukocytosis, peritonitis), but all...
Objective The safety and efficacy of PGG-glucan in surgical patients at high risk for postoperative infection who underwent major thoracic or abdominal surgery were determined. Summary Background Data Recent studies have reported a 25% to 27% infectious complication rate undergoing with an average cost per infected patient $12,000. pretreatment prevention sepsis has been demonstrated rodent models gram-negative gram-positive bacterial yeast infections. In vitro enhanced microbial killing by...
Recent studies have suggested that a subset of patients with Crohn's colitis may favorable outcome after ileal pouch-anal anastomosis and advocated elective in selected disease. We not offered to known disease, but because the overlap clinical presentation ulcerative indeterminate colitis, some receiving an are subsequently found review our experience these identify potential preoperative predictors ultimate pouch failure.Patients final diagnosis disease were identified from registry. These...
PURPOSE: Indications for operative intervention in the treatment of diverticulitis have become unclear. We hypothesized that surgical has decreased resulting proportionately more complicated cases (free perforation and/or abscess). METHODS: conducted a retrospective analysis patients with diverticular disease Nationwide Inpatient Sample from 1991 through 2005. used diagnostic codes to identify all patient discharges and then determined proportion diverticulitis, perforated disease, abscess,...
PURPOSE: Single-incision laparoscopic colectomy represents a potential advance in minimally invasive surgical approaches to colorectal disease. Although widely promoted, outcome data are virtually absent. A group of highly experienced attending surgeons convened standardize technique and prospectively record operative details outcomes. METHODS: was performed by 10 with minimal or no prior single-incision experience. Surgeon rating ergonomics 15 components operation conduct compared...
Intensive postoperative surveillance is associated with improved survival and recommended for patients late stage (stage IIB III) colon cancer. We hypothesized that I IIA cancer would experience similar benefits.
There are various surgical techniques used treat anal fistulas. The adoption and success rates of newer have not been clearly established.The purpose this study was to determine the healing rate after operations for fistulas in New England colorectal surgery practices.We conducted a retrospective review prospectively collected database.The at practices England.A prospective, multicenter registry created by Society Colon Rectal Surgeons. Surgeons were invited collect data regarding patients...
PURPOSE: Inadequate initial differentiation between ulcerative colitis and Crohn's disease may lead to a diagnosis of indeterminate colitis. Construction an ileoanal pouch in these patients result significant morbidity failure when the ultimate is disease. METHOD: We prospectively studied 543 with idiopathic inflammatory bowel determine whether patient's pathologic changed time how it affected outcome. RESULTS: Preoperative was 499 patients, 42 2 patients. Prior colectomy performed 58...
PURPOSE: The aim of this study was to understand better the cause and predictability pouch failure requiring rediversion after ileal pouch-anal anastomosis assess ultimate outcome patients in a large series who required rediversion. METHODS: Data from 460 completing at one institution were recorded both prospectively accumulated registry patient medical records. RESULTS: Of patients, 21 (4.6 percent) underwent Five these subsequently had successful restoration continuity, leaving permanent...
PURPOSE: A notable increase in-hospital admissions for Clostridium difficile colitis has occurred in the United States. In this paper we evaluate changes epidemiology of a subset hospitalized patients with inflammatory bowel diseases. METHODS: retrospective cohort analysis was conducted all disease Nationwide Inpatient Sample, 20 percent stratified random sample national hospital discharge abstracts from 1993 through 2003. Using standard diagnostic codes, identified yearly difficile, other...
Approximately half of Crohn's patients require intestinal resection, and many need repeat resections.The purpose this study was to evaluate the increased risk clinical anastomotic leak in with a history previous resection undergoing anastomosis for disease.This retrospective analysis prospectively collected departmental data 100% capture.The conducted at department colorectal surgery tertiary care teaching hospital between July 2007 March 2016.A cohort consecutive disease who were treated...
Hand-assisted laparoscopic colectomy is thought to facilitate colonic mobilization while maintaining the benefits of surgery. Although previous studies hand-assisted have focused on segmental resection, use restorative proctocolectomy has not been investigated. This study evaluated effectiveness approach compared with a conventional method in patients undergoing proctocolectomy.From prospective database, consecutive series were identified and results compared. Twenty-three patients,...