A5010705038- HIV/AIDS Research and Interventions
- Meta-analysis and systematic reviews
- Health Systems, Economic Evaluations, Quality of Life
- HIV, Drug Use, Sexual Risk
- Delphi Technique in Research
- Mobile Health and mHealth Applications
- Health Policy Implementation Science
- Adolescent Sexual and Reproductive Health
- Ethics in Clinical Research
- HIV/AIDS drug development and treatment
- Global Maternal and Child Health
- Clinical practice guidelines implementation
- HIV Research and Treatment
- HIV-related health complications and treatments
- Healthcare cost, quality, practices
- Primary Care and Health Outcomes
- Health Sciences Research and Education
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Statistical Methods in Clinical Trials
- Medication Adherence and Compliance
- Child Nutrition and Water Access
- Food Security and Health in Diverse Populations
- Health disparities and outcomes
- Vaccine Coverage and Hesitancy
McMaster University
2016-2025
Impact
2017-2025
St. Joseph’s Healthcare Hamilton
2016-2025
McMaster University Medical Centre
2020-2024
Stellenbosch University
2021-2024
Department of Health Research
2018-2024
Central Hospital of Yaoundé
2015-2024
Center for Global Health
2024
Western Cape Department of Health
2021-2024
Hamilton Health Sciences
2016-2023
Sensitivity analyses play a crucial role in assessing the robustness of findings or conclusions based on primary data clinical trials. They are critical way to assess impact, effect influence key assumptions variations—such as different methods analysis, definitions outcomes, protocol deviations, missing data, and outliers—on overall study. The current paper is second series tutorial-type manuscripts intended discuss clarify aspects related methodological issues design analysis In this we...
Background Mobile phone technology is a novel way of delivering health care and improving outcomes. This trial investigates the use motivational mobile text messages (SMS) to improve adherence antiretroviral therapy (ART) over six months. Methodology/Principal Findings CAMPS was single-site randomized two-arm parallel design in Yaoundé, Cameroon. We enrolled HIV-positive adults on ART, aged 21 years above receive weekly standardized message versus usual alone. The primary outcome measured...
Acute respiratory infections (ARI) are a leading cause of morbidity and mortality in under-five children worldwide. About 6.6 million less than 5 years age die every year the world; 95% them low-income countries one third total deaths is due to ARI. This study aimed at determining proportion acute associated risk factors under visiting Bamenda Regional Hospital Cameroon.A cross-sectional analytic involving 512 was carried out from December 2014 February 2015. Participants were enrolled by...
Abstract Introduction : Successful population‐level antiretroviral therapy (ART) adherence will be necessary to realize both the clinical and prevention benefits of scale‐up and, ultimately, end AIDS. Although many people living with HIV are adhering well, others struggle most likely experience challenges in that may threaten virologic suppression at some point during lifelong therapy. Despite importance ART adherence, supportive interventions have generally not been implemented scale. The...
Abstract Virtual reality (VR) for mental health promotion remains understudied in low-income humanitarian settings. We examined the effectiveness of VR reducing depression with urban refugee youth Kampala, Uganda. This randomized controlled trial assessed alone (Arm 1), followed by Group Problem Management Plus (GPM+) 2) and a control group 3), peer-driven convenience sample aged 16–25 Kampala. The primary outcome, depression, was measured Patient Health Questionnaire-9. Secondary outcomes...
Reporting guidelines have been available for the past 17 years since inception of Consolidated Standards Trials statement in 1996. These were developed to improve quality reporting studies medical literature. Despite widespread availability these guidelines, literature remained suboptimal. In this study, we assess current adherence practice guidelines; determine key factors associated with better and provide recommendations enhance future studies.We undertook a systematic scoping review...
Our objectives were to analyse the effects of text messaging versus usual care in improving adherence antiretroviral therapy (ART) people living with HIV using individual patient data meta-analysis. Adjusted, sensitivity and subgroup analyses conducted.3 randomised controlled trials conducted between 2010 2012 rural urban centres Cameroon Kenya (two studies) used.A total 1166 participants included this analysis (Cameroon=200; Kenya=428 538).The primary outcome was ART >95%. The secondary...
Abstract The coronavirus disease 2019 (COVID-19) pandemic and antimicrobial resistance (AMR) are parallel interacting health emergencies that provide the opportunity for mutual learning. As their measures consequences comparable, COVID-19 helps to illustrate potential long-term impact of AMR, which is less acute but not crucial. They may also each other as there a push use existing antimicrobials treat critically ill patients in absence specific treatments. Attempts manage spread lead...