Lora Giangregorio

ORCID: 0000-0002-3739-1805
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Hip and Femur Fractures
  • Bone health and osteoporosis research
  • Cerebral Palsy and Movement Disorders
  • Nutrition and Health in Aging
  • Balance, Gait, and Falls Prevention
  • Physical Activity and Health
  • Spinal Cord Injury Research
  • Musculoskeletal pain and rehabilitation
  • Bone fractures and treatments
  • Frailty in Older Adults
  • Health Policy Implementation Science
  • Geriatric Care and Nursing Homes
  • Health Systems, Economic Evaluations, Quality of Life
  • Spinal Fractures and Fixation Techniques
  • Scoliosis diagnosis and treatment
  • Stroke Rehabilitation and Recovery
  • Bone and Joint Diseases
  • Spine and Intervertebral Disc Pathology
  • Evaluation and Performance Assessment
  • Hip disorders and treatments
  • Delphi Technique in Research
  • Behavioral Health and Interventions
  • Meta-analysis and systematic reviews
  • Clinical practice guidelines implementation
  • Bone health and treatments

Research Institute for Aging
2015-2024

University of Waterloo
2015-2024

Toronto Rehabilitation Institute
2013-2024

University Health Network
2014-2024

Osteoporosis Canada
2023

Institute of Aging
2016-2022

Hamilton Health Sciences
2007-2018

St. Peter's Hospital
2015-2018

McMaster University
2004-2015

Toronto General Hospital
2015

Pilot studies for phase III trials - which are comparative randomized designed to provide preliminary evidence on the clinical efficacy of a drug or intervention routinely performed in many areas. Also commonly know as "feasibility" "vanguard" studies, they assess safety treatment interventions; recruitment potential; feasibility international collaboration coordination multicentre trials; increase experience with study medication trials. They best way large, expensive full-scale study, and...

10.1186/1471-2288-10-1 article EN cc-by BMC Medical Research Methodology 2010-01-06

Sensitivity analyses play a crucial role in assessing the robustness of findings or conclusions based on primary data clinical trials. They are critical way to assess impact, effect influence key assumptions variations—such as different methods analysis, definitions outcomes, protocol deviations, missing data, and outliers—on overall study. The current paper is second series tutorial-type manuscripts intended discuss clarify aspects related methodological issues design analysis In this we...

10.1186/1471-2288-13-92 article EN cc-by BMC Medical Research Methodology 2013-07-16

The Canadian Society for Exercise Physiology assembled a Consensus Panel representing national organizations, content experts, methodologists, stakeholders, and end-users followed an established guideline development procedure to create the 24-Hour Movement Guidelines Adults aged 18–64 years 65 or older: An Integration of Physical Activity, Sedentary Behaviour, Sleep. These guidelines underscore importance movement behaviours across whole 24-h day. process strategy outlined in Appraisal...

10.1139/apnm-2020-0467 article EN cc-by Applied Physiology Nutrition and Metabolism 2020-10-01

Physical inactivity and sedentary behavior increase the risk of chronic illness death. The newest generation "wearable" activity trackers offers potential as a multifaceted intervention to help people become more active.To examine usability usefulness wearable for older adults living with illness.We recruited purposive sample 32 participants over age 50, who had been previously diagnosed illness, including vascular disease, diabetes, arthritis, osteoporosis. Participants were between 52 84...

10.2196/mhealth.4225 article EN cc-by JMIR mhealth and uhealth 2016-01-27

Abstract The study objective was to determine whether diabetes is a risk factor for incident hip or major osteoporotic fractures independent of the WHO fracture assessment tool (FRAX). Men and women with (n = 3518) nondiabetics 36,085) aged ≥50 years at time bone mineral density (BMD) testing (1990 2007) were identified in large clinical database from Manitoba, Canada. FRAX probabilities calculated, outcomes 2008 established via linkage population-based data repository. Multivariable Cox...

10.1002/jbmr.556 article EN Journal of Bone and Mineral Research 2011-11-02

Background: Wearable activity trackers are promising as interventions that offer guidance and support for increasing physical health-focused tracking. Most adults do not meet their recommended daily guidelines, wearable fitness increasingly cited having great potential to improve the levels of adults.

10.2196/mhealth.4461 article EN cc-by JMIR mhealth and uhealth 2016-04-27

The purpose of this overview systematic reviews was to determine the relationship between different types and patterns sedentary behaviour selected health outcomes in adults older adults. Five electronic databases were last searched May, 2019, with a 10-year search limit. Included met priori population (community-dwelling aged 18 years older), intervention/exposure/comparator (various and/or behaviour), criteria. Eighteen included evidence synthesis. High levels are unfavourably associated...

10.1139/apnm-2020-0272 article EN cc-by Applied Physiology Nutrition and Metabolism 2020-10-01

The objective of this overview systematic reviews was to examine the associations between sleep duration and health outcomes in adults. Four electronic databases were searched December 2018 for published previous 10 years. Included met a priori determined population (community-dwelling adults aged 18 years older), intervention/exposure/comparator (various levels duration), outcome criteria (14 examined). To avoid overlap primary studies, we used priority list choose single review per...

10.1139/apnm-2020-0034 article EN cc-by Applied Physiology Nutrition and Metabolism 2020-10-01

In Canada, more than 2 million people live with osteoporosis, a disease that increases the risk for fractures, which result in excess mortality and morbidity, decreased quality of life loss autonomy. This guideline update is intended to assist Canadian health care professionals delivery optimize skeletal prevent fractures postmenopausal females males aged 50 years older.This an 2010 Osteoporosis Canada clinical practice on diagnosis management osteoporosis Canada. We followed Grading...

10.1503/cmaj.221647 article EN cc-by-nc-nd Canadian Medical Association Journal 2023-10-09

Background: Multi-channel surface functional electrical stimulation (FES) for walking has been used to improve voluntary and balance in individuals with spinal cord injury (SCI).Objective: To investigate short-and long-term benefits of 16 weeks thrice-weekly FES-assisted program, while ambulating on a body weight support treadmill harness system, versus non-FES exercise improvements gait chronic incomplete traumatic SCI, randomized controlled trial design.Methods: Individuals (≥18 months)...

10.1179/2045772314y.0000000263 article EN Journal of Spinal Cord Medicine 2014-09-01
Coming Soon ...