A5055518070- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Poverty, Education, and Child Welfare
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Global Maternal and Child Health
- HIV Research and Treatment
- Child Nutrition and Water Access
- HIV/AIDS Impact and Responses
- HIV, Drug Use, Sexual Risk
- Adolescent and Pediatric Healthcare
- Pneumocystis jirovecii pneumonia detection and treatment
- Homelessness and Social Issues
- Ethics in Clinical Research
- Mobile Health and mHealth Applications
- Maternal Mental Health During Pregnancy and Postpartum
- Ethics and Legal Issues in Pediatric Healthcare
- Gestational Diabetes Research and Management
- Tuberculosis Research and Epidemiology
- COVID-19 Impact on Reproduction
- Viral gastroenteritis research and epidemiology
- Pediatric Pain Management Techniques
- Child Abuse and Trauma
- Global Health and Surgery
- Vaccine Coverage and Hesitancy
Mount Sinai Health System
2019-2025
Icahn School of Medicine at Mount Sinai
2019-2025
AMPATH
2014-2024
Moi University
2013-2024
Mount Sinai Hospital
2021-2024
Indiana University – Purdue University Indianapolis
2011-2021
Indiana University School of Medicine
2011-2021
Indiana University
2012-2021
New York City Health and Hospitals Corporation
2020
Riley Hospital for Children
2012-2019
Abstract Introduction : Successful population‐level antiretroviral therapy (ART) adherence will be necessary to realize both the clinical and prevention benefits of scale‐up and, ultimately, end AIDS. Although many people living with HIV are adhering well, others struggle most likely experience challenges in that may threaten virologic suppression at some point during lifelong therapy. Despite importance ART adherence, supportive interventions have generally not been implemented scale. The...
In resource-limited settings, beliefs about disclosing a child's HIV status and the subsequent impacts of disclosure have not been well studied. We sought to describe how parents guardians HIV-infected children view impact status, particularly for children's antiretroviral therapy (ART) adherence. A qualitative study was conducted using involving focus groups interviews with receiving ART in western Kenya. Interviews covered multiple aspects experience having take medicines. Transcribed...
Background Globally, the population of adolescents living with perinatally acquired HIV (APHs) continues to expand. In this study, we pooled data from observational pediatric cohorts and cohort networks, allowing comparisons in "real-life" settings across multiple regions. We describe geographic temporal characteristics mortality outcomes APHs regions, including South America Caribbean, North America, Europe, sub-Saharan Africa, Southeast Asia. Methods findings Through Collaborative...
Keywords: HIV, antiretroviral therapy, access, adherence, resource-limited settings
Introduction Disclosure of HIV status to children is essential for disease management but not well characterized in resource-limited settings. This study aimed describe the prevalence disclosure and associated factors among a cohort HIV-infected adolescents Kenya. Methods We conducted cross-sectional study, randomly sampling ages 6–14 years attending 4 clinics western Data were collected from questionnaires administered by clinicians their caregivers, supplemented with chart review....
Researchers and aid organizations have reported that orphans in sub-Saharan Africa (SSA) are particularly vulnerable to abuse neglect. This article is a review of qualitative studies address experiences maltreatment among orphaned children youth living extended families SSA. It aims inform policy programming by providing better understanding the types encountered perceived risk factors. A literature search was carried out using Google, PubMed, Scholars Portal Search Scopus. Searches relevant...
The objective of this study was to identify the vital status and reasons for children becoming loss follow-up (LTFU) from a large program in western Kenya.
<h3>Background</h3> The most important reason for childhood cancer treatment failure in low-income countries is abandonment. <h3>Objective</h3> aim of this study was to explore reasons abandonment and assess the clinical condition these children. <h3>Design</h3> This a descriptive using semistructured questionnaires. Home visits were conducted interview families patients, diagnosed between January 2007 2009, who had abandoned at Moi Teaching Referral Hospital (MTRH). <h3>Results</h3> Between...
Introduction As highly active antiretroviral therapy (HAART) transforms human immunodeficiency virus (HIV) into a manageable chronic disease, new challenges are emerging in treating children born with HIV, including number of risks to their physical and psychological health due HIV infection its lifelong treatment. Methods We conducted literature review evaluate the evidence on effects perinatal (PHIV+) treatment era HAART, major comorbidities. Results discussion Perinatally infected face...
Abstract Introduction We assessed mortality and losses to follow‐up ( LTFU ) during adolescence in routine care settings the International epidemiology Databases Evaluate AIDS (Ie DEA consortium. Methods Cohorts Asia‐Pacific, Caribbean, Central, South America, sub‐Saharan Africa (Central, East, Southern, West) contributed data, included adolescents living with HIV ALHIV enrolled from January 2003 aged 10 19 years (period of adolescence) while under up database closure (June 2016). Follow‐up...
Stigma shapes all aspects of HIV prevention and treatment, yet there are limited data on how HIV-infected youth their families affected by stigma in sub-Saharan Africa. The authors conducted a qualitative study using focus group discussions among 39 adolescents receiving care at clinics western Kenya 53 caregivers children. Participants felt that while knowledge access to treatment were increasing, many community members still held negative inaccurate views about HIV, including associating...
Mobile technologies represent potentially novel and scalable intervention delivery platforms for adolescents living with HIV (ALWH) in low- middle-income countries. We conducted a prospective, mixed methods pilot study to evaluate the acceptability feasibility of WhatsApp® platform deliver individual counseling services facilitate peer support ALWH western Kenya. Thirty (17 female, mean age 15.4) on ART, engaged care aware their status, were enrolled. After 6 months, participants described...
Global health researchers often discount mutual learning and benefit to address shared challenges across high low- middle-income settings. Drawing from a 30-year partnership called AMPATH that started between Indiana University in the US Moi Kenya, we describe an innovative approach program for coined 'reciprocal innovation.' Reciprocal innovation harnesses bidirectional, co-constituted, iterative exchange of ideas, resources, innovations diverse global The success particularly HIV/AIDS...
Objective To describe the nutritional status of orphaned and separated children adolescents (OSCA) living in households community (HH), on street, those institutional environments western Kenya. Methods The study enrolled OSCA from 300 randomly selected 19 Charitable Children's Institutions (CCIs), 100 street-involved children. Measures malnutrition were standardized with Z-scores using World Health Organization criteria; ≤-2 standard deviations (sd) moderate-severe malnutrition. Data...
Introduction High levels of adherence to antiretroviral therapy (ART) are central HIV management. The objective this study was compare multiple measures and investigate factors associated with among HIV‐infected children in western Kenya. Methods We evaluated ART prospectively for six months aged ≤14 years attending a large outpatient clinic Adherence reported using caregiver report, plasma drug concentrations Medication Event Monitoring Systems (MEMS ® ). Kappa statistics were used...
International collaborators face challenges in the design and implementation of ethical biomedical research. Evaluating community understanding research processes like informed consent may enable researchers to better protect participants a particular setting; however, there exist few studies examining perspectives health research, particularly resource-limited settings, or strategies for engaging processes. Our goal was inform practice setting western Kenya similar settings. We sought use...
Abstract Background Community-based participatory research (CBPR) is a collaborative approach to that involves the equitable participation of those affected by an issue. As field global public health grows, potential CBPR build capacity and engage communities in identification problems development implementation solutions sub-Saharan Africa has yet be fully tapped. The Orphaned Separated Children’s Assessments Related their Health Well-Being (OSCAR) project longitudinal cohort orphaned...