A5018705503- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Impact and Responses
- Global Maternal and Child Health
- HIV, Drug Use, Sexual Risk
- Homelessness and Social Issues
- Poverty, Education, and Child Welfare
- Child Nutrition and Water Access
- HIV-related health complications and treatments
- Adolescent and Pediatric Healthcare
- Community Health and Development
- Mobile Health and mHealth Applications
- Health Policy Implementation Science
- Mental Health and Patient Involvement
- Gestational Diabetes Research and Management
- HIV Research and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- ICT in Developing Communities
- Participatory Visual Research Methods
- COVID-19 Clinical Research Studies
- Migration, Health and Trauma
- Ethics in Clinical Research
- Substance Abuse Treatment and Outcomes
- Innovative Human-Technology Interaction
- Vaccine Coverage and Hesitancy
AMPATH
2014-2025
Moi University
2014-2025
University of Toronto
2019-2025
Manipal Teaching Hospital
2017-2023
Mobile technologies represent potentially novel and scalable intervention delivery platforms for adolescents living with HIV (ALWH) in low- middle-income countries. We conducted a prospective, mixed methods pilot study to evaluate the acceptability feasibility of WhatsApp® platform deliver individual counseling services facilitate peer support ALWH western Kenya. Thirty (17 female, mean age 15.4) on ART, engaged care aware their status, were enrolled. After 6 months, participants described...
Abstract Introduction There are approximately 1.7 million adolescents living with HIV (ALHIV, ages 10 to 19) globally, including 110,000 in Kenya. While ALHIV experience poor retention care, limited data exist on factors underlying disengagement. We investigated the burden of trauma among disengaged western Kenya, and its potential role care Methods performed in‐depth qualitative interviews who had from at two sites, their caregivers healthcare workers (HCW) 2018 2020. Disengagement was...
Introduction Adolescents living with HIV (ALHIV, ages 10–19) experience complex challenges to adhere antiretroviral therapy (ART) and remain in care, may be vulnerable wide-scale disruptions during the COVID-19 pandemic. We assessed for a range of effects pandemic on ALHIV western Kenya, whether were greater recent histories being lost program (LTP). Methods recruited from an ongoing prospective study at 3 sites Kenya. The parent enrolled participants February 2019–September 2020, into...
Research suggests a burden of HIV among street-connected youth (SCY) in Kenya. We piloted the use peer navigators (PNs), individuals mixed serostatus and with direct experience being street-connected, to link SCY testing care. From January 2015 October 2017, PNs engaged 781 (585 male, 196 female), median age 16 (IQR 13-20). At initial encounter, 52 (6.6%) were known HIV-positive 647 (88.8%) agreed testing. Overall, 63/781 (8.1%) this program HIV-positive; 4.6% males 18.4% females (p <...
Despite the central role of caregivers in managing HIV treatment for children living with HIV, viral suppression within caregiver-child dyads which both members are is not well described. We conducted a retrospective analysis <15 years age and their attending clinics affiliated Academic Model Providing Access to Healthcare (AMPATH) Kenya between 2015 2017. To be included analysis, must have had ≥1 load (VL) during study period while receiving antiretroviral therapy (ART) ≥6 months, date...
Introduction: Mobile technologies represent a scalable platform for delivering knowledge and interventions targeting adolescents living with HIV (ALWH) in low middle income countries. Data from mobile can be used to assess the contextual understanding experiences of ALWH. Methods: We examined HIV-related knowledge, attitudes, beliefs, behaviors, Kenyan ALWH revealed data enrollment WhatsApp® group chat intervention. Results: Thirty (17 female, mean age 15.4) on ART, engaged care aware their...
Long-acting antiretroviral treatment (LA ART) is a forthcoming option for adolescents and young people living with HIV (AYPLHIV), but perspectives on using peer mentors to implement LA ART AYPLHIV are unknown. We conducted seven focus group discussions ( n = 58 participants) from November 2021 April 2022 in Kenya four stakeholder groups, including AYPLHIV, healthcare providers, advocates, policymakers. used inductive coding thematic analysis. Our stakeholders articulated crucial the...
Introduction Adolescents and young people living with HIV (AYPLHIV) face significant hurdles in adhering to daily oral antiretroviral therapy (ART). Long-acting (LA) ART, such as injectable cabotegravir rilpivirine, may help overcome these hurdles. However, little is known about the perceived benefits barriers LA ART usage by AYPLHIV resource-limited settings. Methods We conducted focus group discussions (FGDs) four target groups of adolescents/youth, providers, policymakers, other advocates...
Abstract Introduction Adolescent and youth‐friendly health services (AYFHS) have been promoted as a best practice for adolescents young people living with HIV (AYLH). However, thorough descriptions of AYFHS AYLH remain scarce. We sought to characterize adolescent‐friendly in global paediatric research consortium. Methods Cross‐sectional data were collected from 16 sites the Young Adult Network IeDEA (AYANI) International epidemiology Databases Evaluate AIDS consortium between August 2020...
Adolescents living with HIV (ALHIV, ages 10–19) are retained in care at low rates, resulting poor clinical outcomes. We investigated barriers and facilitators to retention experienced by perinatally infected ALHIV western Kenya. This qualitative study purposefully sampled hospitalized (engaged not currently engaged care), outpatient care, caregivers of ALHIV. In total, 116 participated interviews or focus group discussions. Challenges related the effects both stigma poverty multiple...
Objective To obtain an estimate of the size of, and human immunodeficiency (HIV) prevalence among, young people children living on streets Eldoret, Kenya.Methods We counted using a point-in-time approach, ensuring we reached our target population by engaging relevant community leaders during planning study.We acquired count data over period 1 week between hours 08:00 23:00, from both stationary site mobile teams.Participants provided demographic fingerprint (to avoid double-counting) were...
Introduction The objective of this study was to determine the growth patterns, rates malnutrition, and factors associated with malnutrition in children born HIV-infected mothers western Kenya using data from an electronic medical record system. Methods This a retrospective chart review (HIV+) and–exposed (HEU) (<5 years) collected prospectively course routine clinical care stored system between January 2011 August 2016. Demographics anthropometrics were described, Chi-square testing compare...
Abstract Introduction Adolescents living with HIV are subject to multiple co‐morbidities, including growth retardation and immunodeficiency. We describe CD4 evolution during adolescence using data from the Collaborative Initiative for Paediatric Education Research (CIPHER) global project. Methods Data were collected between 1994 2015 11 CIPHER networks worldwide. perinatally acquired infection (APH) who initiated antiretroviral therapy (ART) before age 10 years, at least one height or count...
Abstract Introduction Adolescents living with HIV (ALHIV, ages 10–19) experience complex barriers to care engagement. Challenges surrounding status disclosure or non-disclosure adolescents may contribute adolescent disengagement from non-adherence ART. We performed a qualitative study investigate the contribution of challenges care. Methods This was disengaged ALHIV and their caregivers, healthcare workers (HCW) in Academic Model Providing Access Healthcare (AMPATH) program western Kenya....
HIV has transformed from a serious acute illness with high rates of morbidity and mortality to fairly easily managed chronic disease. However, children adolescents living are yet achieve similar improvement in their care outcomes compared adults. There have been number studies assessing the reasons for slower these age categories, mainly focusing on health systems, drug- family- related barriers ART adherence children. We sought explore school-related through in-depth interviews students...
UNICEF estimates that there are as many 100 million street-involved youth (SIY) globally. Marginalized conditions put SIY at higher risk of HIV and adverse outcomes once HIV-positive. The objective this analysis was to describe barriers facilitators accessing prevention, testing, treatment services Phase I an implementation study evaluating the use peer navigators increase access services.
Abstract Background Youth in sub-Saharan Africa are at high risk of substance use yet lack access to interventions. The goal this project was evaluate the feasibility and acceptability a peer-delivered, single-session screening brief intervention program for youth Kenya. Methods This convergent parallel mixed methods study utilizing both quantitative qualitative approaches. Two trained peer providers administered 100 aged 15–24 years. To implementation intervention, we collected data....
Adolescents living with HIV (ALHIV) may be vulnerable to widescale impacts of the COVID-19 pandemic and health system responses which impact care. We assessed healthcare worker (HCW) perspectives on adolescent care delivery engagement in western Kenya.We performed in-depth qualitative interviews HCW at 10 clinical sites Academic Model Providing Access Healthcare Kenya, from January March, 2021. Semistructured ascertained pandemic-related retention.Interviews were conducted 22 HCWs clinics....
Abstract Introduction Adolescents living with HIV (ALHIV, ages 10–19) have developmentally specific needs in care, and lower retention compared to other age groups. Family‐level contexts may be critical adolescent outcomes, but often been overlooked. We investigated family‐level factors underlying disengagement supporting re‐engagement among adolescents disengaged from care. Methods Semi‐structured interviews were performed 42 ALHIV, 32 of their caregivers 28 healthcare workers (HCW) the...
Overwhelmed, under-trained medical staff working in resource-limited settings need efficient resources for HIV disclosure counselling. The objective of this study was to describe providers' experiences using tablet computers disclosure-related counselling with HIV-infected children and their caregivers western Kenya, additional perspectives from adolescents. A qualitative design implemented at three clinics Kenya (Bumala, Busia Port Victoria) within the Academic Model Providing Access...
For adolescents living with HIV (ALWH), school may be the most important but understudied social sphere related to stigma. Teachers are role models in classroom and within community, their attitudes behavior towards people have critical psychosocial treatment ramifications. Altering teachers' knowledge, beliefs (K/A/B) about could reduce stigmatizing content teaching, classrooms school, improving environment for ALWH.
Introduction: Understanding community members' knowledge, attitudes, and beliefs about the novel SARS-CoV-2 virus prevalence of associated stigma are critical steps for increasing accurate public health encouraging uptake preventative or mitigating behaviors, ultimately bringing COVID-19 pandemic under control. Methods: We conducted a one-time, phone-based assessment to assess presence perceived reported by Kenyan primary secondary school teachers, as well adolescents living with HIV....