A5069608211- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Obesity and Health Practices
- Food Security and Health in Diverse Populations
- Bariatric Surgery and Outcomes
- Breastfeeding Practices and Influences
- Birth, Development, and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Mobile Health and mHealth Applications
- Sleep and related disorders
- Eating Disorders and Behaviors
- Pregnancy and preeclampsia studies
- Diabetes Treatment and Management
- Diet and metabolism studies
- Child and Adolescent Health
- Health Literacy and Information Accessibility
- Sleep and Wakefulness Research
- Physical Activity and Health
- Healthcare Systems and Technology
- Pregnancy-related medical research
- Geriatric Care and Nursing Homes
- Social Media in Health Education
- Metabolism, Diabetes, and Cancer
- Pancreatitis Pathology and Treatment
- Dietetics, Nutrition, and Education
Temple University
2015-2024
Patient-Centered Outcomes Research Institute
2023
Creative Commons
2023
Thomas Jefferson University
2023
Children's Hospital of Philadelphia
2023
Duke University
2023
University of Mississippi Medical Center
2019
National Institute of General Medical Sciences
2019
Royal Berkshire NHS Foundation Trust
2016
Filadelfia
2010
OBJECTIVE This trial compared the efficacy and safety of first oral glucagon-like peptide 1 (GLP-1) receptor agonist, semaglutide, as monotherapy with placebo in patients type 2 diabetes managed by diet exercise alone. Two estimands addressed two efficacy-related questions: a treatment policy estimand (regardless product discontinuation or rescue medication use) (on without all randomized patients. RESEARCH DESIGN AND METHODS was 26-week, phase 3a, randomized, double-blind,...
Efficacy and safety of the glucagon-like peptide 1 (GLP-1) analog oral semaglutide sodium-glucose cotransporter 2 inhibitor empagliflozin were compared in patients with type diabetes uncontrolled on metformin.Patients randomized to once-daily open-label treatment 14 mg (n = 412) or 25 410) a 52-week trial. Key end points change from baseline week 26 HbA1c (primary) body weight (confirmatory secondary). Two estimands addressed efficacy-related questions: policy (regardless trial product...
Objective: Despite the increased emphasis on obesity and diet-related diseases, nutrition education remains lacking in many internal medicine training programs. We evaluated attitudes, self-perceived proficiency, knowledge related to clinical among a cohort of interns.Methods: Nutrition attitudes proficiency were measured using previously validated questionnaires. Knowledge was assessed with multiple-choice quiz. Subjects asked whether they had prior training.Results: Of 114 participants, 61...
Evidence is lacking regarding effective and sustainable weight loss approaches for use in the primary care setting. We conducted a 12‐week randomized controlled trial to evaluate short‐term efficacy of web‐based intervention among 101 patients with obesity hypertension. Patients had access comprehensive website that used moderate‐intensity approach designed specifically implementation. also participated four (two in‐person two telephonic) counseling sessions health coach. Intent‐to‐treat...
Evidence is lacking regarding effective weight control treatments in pregnancy for ethnic minority women with obesity. This study evaluated whether a technology-based behavioral intervention could decrease the proportion of African American overweight or obesity who exceeded Institute Medicine (IOM) guidelines gestational gain.We conducted two-arm pilot randomized clinical trial. Participants were 66 socioeconomically disadvantaged pregnant (12.5 ± 3.7 weeks' gestation; 36% overweight, 64%...
Objective To compare the efficacy of non-nutritive sweetened beverages (NNS) or water for weight loss during a 12-week behavioral treatment program. Methods An equivalence trial design with NNS as main factor in prospective randomized among 303 men and women was employed. All participants participated The results phase (12 weeks) an ongoing (1 year) that is also evaluating effects these two treatments on maintenance were reported. Results not equivalent beverage group losing significantly...
Objective To evaluate the effects of water versus beverages sweetened with non‐nutritive sweeteners (NNS) on body weight in subjects enrolled a year‐long behavioral loss treatment program. Methods The study used randomized equivalence design NNS or as main factor trial among 303 weight‐stable people overweight and obesity. All participants participated program plus assignment to consume 24 ounces (710 ml) daily for 1 year. Results treatments were non‐equivalent, showing greater at end At...
To examine the extent to which early postpartum depression is associated with weight retention 1 year after childbirth.
Excessive gestational weight gain promotes poor maternal and child health outcomes. Weight misperception is associated with in non-pregnant women, but no data exist during pregnancy. The purpose of this study was to examine the association misperceived pre-pregnancy body status excessive gain. At enrollment, participants Project Viva reported weight, height, perceived by questionnaire. Our sample comprised 1537 women who had either normal or overweight/obese BMI. We created 2 categories...
Objective: Maternal obesity is associated with adverse pregnancy outcomes. To improve outcomes, obstetric providers must effectively evaluate and manage their obese pregnant patients. We sought to determine the knowledge, attitudes, practice patterns of regarding in pregnancy. Methods: In 2007–2008, we surveyed 58 practicing obstetricians, nurse practitioners, certified nurse-midwives at a multispecialty Massachusetts. administered 26-item questionnaire that included provider self-reported...
Abstract IMPORTANCE Prior studies have demonstrated the effectiveness of COVID-19 vaccines in children and adolescents. However, benefits vaccination these age groups with prior infection remain underexplored. OBJECTIVE To evaluate preventing reinfection various Omicron subvariants (BA.1/2, BA.4/5, XBB, later) among 5- to 17-year-olds SARS-CoV-2 infection. DESIGN A target trial emulation through nested designs distinct study periods. SETTING The utilized data from Research COVID Enhance...
This study examined the efficacy of a commercially available, portion-controlled diet (PCD) on body weight and HbA1c over 6 months in obese patients with type 2 diabetes.One-hundred participants mean±s.d. age 55.6±10.6 year, 102.9±18.4 kg 7.7±1.3% were randomly assigned to 9-session group lifestyle intervention that included PCD or program diabetes self-management education (DSME). Participants two groups prescribed same goals for energy intake (1250-1550 kcal per day) physical activity (200...
Efforts to prevent postpartum weight retention in extant clinical trials of African American women have proven exceedingly challenging. The primary purpose this pilot study was determine whether a behavioral intervention implemented early pregnancy through 6 months could increase the proportion who were at or below their weights by postpartum. We additionally evaluated mothers' loss be maintained 12 Participants 66 socioeconomically disadvantaged (36% overweight, 64% obese) randomly assigned...