A5015347623- Spine and Intervertebral Disc Pathology
- Bone health and osteoporosis research
- Plant Stress Responses and Tolerance
- Postharvest Quality and Shelf Life Management
- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Bone and Joint Diseases
- Photosynthetic Processes and Mechanisms
- MicroRNA in disease regulation
- Multiple Myeloma Research and Treatments
- Circular RNAs in diseases
- Scoliosis diagnosis and treatment
- Bone Metabolism and Diseases
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Plant Molecular Biology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cervical and Thoracic Myelopathy
- Adipokines, Inflammation, and Metabolic Diseases
- Plant Gene Expression Analysis
- Animal Behavior and Reproduction
- Plant Pathogens and Fungal Diseases
- Medical Imaging and Analysis
- Adipose Tissue and Metabolism
Dynamique du noyau
2025
State Key Laboratory of Molecular Reaction Dynamics
2025
Dalian Institute of Chemical Physics
2025
Chinese Academy of Sciences
2025
Sun Yat-sen University
2020-2024
The First Affiliated Hospital, Sun Yat-sen University
2020-2024
Key Laboratory of Guangdong Province
2022-2023
Guangdong Provincial People's Hospital
2022
Third Affiliated Hospital of Southern Medical University
2021
China Agricultural University
2010-2012
Songbirds have one of the most accessible neural systems for study brain mechanisms behavior. However, neuroethological studies in songbirds been limited by lack high-throughput molecular resources and gene-manipulation tools. To overcome these limitations, we constructed 21 regular, normalized, subtracted full-length cDNA libraries from brains zebra finches 57 developmental behavioral conditions an attempt to clone as much transcriptome possible. From libraries, approximately 14,000...
Defect passivation engineering, an effective strategy to optimize grain boundaries and reduce defects in organic-inorganic hybrid perovskites, has been widely used improve device performance; however, knowledge of its impact on the carrier transport property is still limited. Herein, we take carbon dot (CD) as example explore effect surface modification longitudinal diffusivity (D) CH3NH3PbI3 perovskite films by using transient reflection spectroscopy. The results show that D value...
Background: Osteoporotic vertebral compression fracture (OVCF) is a common disease in elderly population, which could cause serious back pain and has substantial impact on patients’ health-related quality of life (HRQoL). The aim this study was to identify the effect Teriparatide as conservative treatment reducing pain, improving for postmenopausal women with osteoporotic fractures.Methods: In 12-month, retrospective study, 112 OVCFs were assigned group (20 µg Teriparatide, subcutaneous,...
Abstract Background With the increase in life expectancy, a large number of patients with osteoporosis (OP) are undergoing spine surgery, which may adversely affect surgical success rate. The prevalence OP varies different regions, and no data available that represent among Chinese over 50 years age who surgery. It was first multicenter study to assess these patients. Aiming obtain comprehensive data, this combined bone mineral density (BMD) measurements visual radiography assessment (VRA)...
Background. Circular RNAs (circRNAs) contribute to the regulation of many diseases. However, little is known about role circRNAs in development glucocorticoid-induced osteoporosis (GIOP). The present study aimed at systematically characterizing circRNA expression profiles GIOP and predict potential functions associated regulatory networks. Methods. A small animal model was developed Sprague-Dawley rats given daily intraperitoneal doses synthetic glucocorticoid dexamethasone. Micro-CT bone...
Objective: Postmenopausal osteoporosis (PMOP), a chronic systemic metabolic disease prevalent in middle-aged and elderly women, heavily relies on bone mineral density (BMD) measurement as the diagnostic indicator. In this study, we investigated serum microRNAs (miRNAs) possible screening tool for PMOP. Methods: This investigation recruited 83 eligible participants from 795 community-dwelling postmenopausal women between June 2020 August 2021. The miRNA expression profiles of PMOP patients...
Abstract Purpose To analyze the association between scoliosis and vertebral refracture after percutaneous kyphoplasty (PKP) in patients with osteoporotic compression fractures (OVCFs). Methods A retrospective study was conducted on 269 meeting criteria from January 2014 to October 2022. All underwent PKP complete data were followed-up for > 12 months. First, it verified that a risk factor patients. Second, grouped based Cobb angle evaluate impact of post-operative angle. The cox...
While serum bone turnover markers (BTMs) and mineral density (BMD) have been confirmed as useable risk assessment tools for postmenopausal osteoporosis, the associations between BTMs BMD changes are still ambiguous. The aim of this study was to explore underlying in women.Between January 2015 October 2020, 135 women were retrospectively enrolled. They divided into two groups according lumbar spine (LS) 1-4 change (1 y T-score minus baseline T-score, Group 1 [n = 36] < 0 2 99] ≥ 0)....
SummaryTo reveal details of the role(s) abscisic acid (ABA) during fruit ripening and regulation ABA levels, two 9-cis-epoxycarotenoid dioxygenase genes (DkNCED1 DkNCED2) DkCYP707A1 gene for 8'-hydroxylase were isolated from unripened persimmon fruit. Expression DkNCED1 increased at start maturation peaked 20 d before harvest, which was consistent with accumulation in persimmon. DkNCED2 high immature stage, then declined continuously throughout ripening. Compared to DkNCED genes, expression...
While the prognosis of multiple myeloma (MM) has significantly improved over last decade because new treatment options, it remains incurable. Aetiological explanations and biological targets based on genomics may provide additional help for rational disease intervention.Three microarray datasets associated with MM were downloaded from Gene Expression Omnibus (GEO) database. GSE125364 GSE39754 used as training set, GSE13591 was verification set. The differentially expressed genes (DEGs)...
Prevention of fragility fractures is one the public health priorities worldwide, whilst incidence osteoporotic vertebral compression (OVCF) continues to rise and lacks corresponding accurate prediction model. This study aimed screen potential causes risk factors for primary non-traumatic (NTOVCF) in elderly by characterizing a patient population with NTOVCF comparing it patients.Between January 2013 2022, 208 patients unequivocal evidence bone manifested as painful were enrolled, compared...
Background Anoikis resistance is a prerequisite for the successful development of osteosarcoma (OS) metastases, whether expression anoikis-related genes (ARGs) correlates with OS prognosis remains unclear. This study aimed to investigate feasibility using ARGs as prognostic tools risk stratification OS. Methods The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases provided transcriptome information relevant GeneCards database was used identify ARGs. Differentially...
Background/Objectives: Alterations in the body mass index (BMI) and percent fat (PBF) have been considered to be related aging-induced changes bone muscle. This study aimed evaluate associations of BMI PBF with osteoporosis, sarcopenia, osteosarcopenia postmenopausal women. Methods: A total 342 participants who underwent musculoskeletal function assessments at First Affiliated Hospital Sun Yat-sen University between January 2015 December 2022 were retrospectively screened. The diagnosis...
Therapy of very severe osteoporotic compression fractures (VSOVCF) has been a growing challenge for spine surgeons. Opinions vary regarding the optimal surgical procedure treatment VSOVCF and which internal fixation method is more effective still under debate, research on this topic lacking. This retrospective study was conducted to compare efficacy safety various pedicle screw methods treating VSOVCF.This single-center comparative between January 2015 September 2020. Two hundred one...
The diffusion tensor imaging (DTI) parameters (fractional anisotropy [FA] and apparent coefficient [ADC]) are commonly used to provide quantitative information on tissues. This study aimed evaluate the predictive value of preoperative DTI spinal nerve roots in surgical outcome lumbar disc herniation (LDH).A total 117 LDH patients were included. According postoperative improvement rate, dichotomized into unfavorable group (N.=35) favorable (N.=82).The had a younger age (P=0.005) shorter...