- Phytochemicals and Antioxidant Activities
- Bee Products Chemical Analysis
- Sirtuins and Resveratrol in Medicine
- Antioxidant Activity and Oxidative Stress
- Essential Oils and Antimicrobial Activity
- Skin Protection and Aging
- Phytochemistry Medicinal Plant Applications
- Natural Antidiabetic Agents Studies
- Botanical Research and Applications
- Insect and Pesticide Research
- Microbial Metabolites in Food Biotechnology
- Pomegranate: compositions and health benefits
- Calcium signaling and nucleotide metabolism
- Nutrition, Genetics, and Disease
- Medicinal Plants and Bioactive Compounds
- Consumer Attitudes and Food Labeling
- PARP inhibition in cancer therapy
- Mitochondrial Function and Pathology
- Food Science and Nutritional Studies
- Plant Gene Expression Analysis
- Tea Polyphenols and Effects
- Healthcare and Venom Research
- Genomics, phytochemicals, and oxidative stress
- Edible Oils Quality and Analysis
- Autophagy in Disease and Therapy
Marche Polytechnic University
2016-2025
Ospedali Riuniti di Ancona
2015-2019
University of Hong Kong
2018
University of Macau
2018
Leiden University
2018
University of Kentucky
2018
Universidad Europea del Atlántico
2018
Seoul National University
2018
This study investigates the protective effect of Sveva strawberry polyphenol-rich extract on human dermal fibroblasts against AAPH-induced oxidative stress. The HPLC-DAD/ESI-MS analysis was used for evaluating phenolic composition fruits. presented a high anthocyanin content (639.79 mg per kg fresh fruit), representing ∼86.08% total content, with Pg-3-glc as most abundant representative (611.18 fruit). Only one ellagitannin (agrimoniin) identified, while two quercetins, three kaempherol...
Strawberry bioactive compounds are widely known to be powerful antioxidants. In this study, the antioxidant and anti-aging activities of a polyphenol-rich strawberry extract were evaluated using human dermal fibroblasts exposed H2O2. Firstly, phenol flavonoid contents studied, as well capacity. HPLC-DAD analysis was performed determine vitamin C β-carotene concentration, while HPLC-DAD/ESI-MS used for anthocyanin identification. presented high capacity, relevant concentration vitamins...
Food fortification through the increase and/or modulation of bioactive compounds has become a major goal for preventing several diseases, including cancer. Here, strawberry lines cv. Calypso transformed with construct containing an anthocyanidin synthase (ANS) gene were produced to study effects on anthocyanin biosynthesis, metabolism, and transcriptome. Three ANS transgenic (ANS L5, L15, L18) analyzed phytochemical composition total antioxidant capacity (TAC), their fruit extracts assessed...
Abstract We describe the biological effects of a polyphenol-rich strawberry extract (PRSE), obtained from “Alba” variety, on highly aggressive and invasive basal-like breast cancer cell line A17. Dose-response time-course experiments showed that PRSE is able to decrease cellular viability A17 cells in time- dose-dependent manner. effect survival was investigated other tumor normal lines both mouse human origin, demonstrating more active against cells. Cytofluorimetric analysis demonstrated...
Honey is a natural product known to modulate several biological activities including cancer. The aim of the present study was examine phytochemical content and antioxidant activity Strawberry tree (Arbutus unedo) honey (STH) its cytotoxic properties against human colon adenocarcinoma (HCT-116) metastatic (LoVo) cell lines in comparison with Manuka (Leptospermum scoparium) (MH). Several unifloral STH MH were analyzed for their phenolic, flavonoid, amino acid protein contents, as well radical...
Regulation of lipid metabolism is essential for treatment and prevention several chronic diseases such as obesity, diabetes, cardiovascular diseases, which are responsible most deaths worldwide. It has been demonstrated that the AMP-activated protein kinase (AMPK) a direct impact on by modulating downstream-signaling components. The main objective present work was to evaluate in vitro effect methanolic strawberry extract AMPK its possible repercussion human hepatocellular carcinoma cells...