A5050772423- Porphyrin and Phthalocyanine Chemistry
- Supramolecular Chemistry and Complexes
- Molecular Sensors and Ion Detection
- DNA and Nucleic Acid Chemistry
- Metal complexes synthesis and properties
- Supramolecular Self-Assembly in Materials
- Advanced biosensing and bioanalysis techniques
- Luminescence and Fluorescent Materials
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Organometallic Compounds Synthesis and Characterization
- Molecular spectroscopy and chirality
- Spectroscopy and Quantum Chemical Studies
- Porphyrin Metabolism and Disorders
- Ubiquitin and proteasome pathways
- Protein Interaction Studies and Fluorescence Analysis
- Surface Chemistry and Catalysis
- Analytical Chemistry and Chromatography
- Photochemistry and Electron Transfer Studies
- Origins and Evolution of Life
- Photodynamic Therapy Research Studies
- Thermal and Kinetic Analysis
- Analytical Chemistry and Sensors
- Photoreceptor and optogenetics research
- Chemical Thermodynamics and Molecular Structure
University of Catania
2016-2025
National Interuniversity Consortium of Materials Science and Technology
2020
Columbia University
2011
University of Wyoming
2011
University of Messina
1990-2011
Institute of Biostructure and Bioimaging
2002-2009
Doane University
2009
National Academy of Sciences of Ukraine
2005
Louisiana State University
2004
Princeton University
1989-1991
Abstract The chirality of (nano)structures is paramount in many phenomena, including biological processes, self-assembly, enantioselective reactions, and light or electron spin polarization. In the quest for new chiral materials, metallo-organic hybrids have been attractive candidates exploiting aforementioned scientific fields. Here, we show that carbon nanoparticles, called nanodots, can be readily prepared using hydrothermal microwave-assisted synthesis easily purified. These particles,...
The presence of 10-13 M chiral clusters aromatic amino acids addresses aggregation opposite-charged achiral porphyrin towards the formation smart assemblies. latter supramolecular complexes are able to self-propagate and transfer their information with a 100% yield. bias occurs through correlated sequence induction, memory, amplification chirality that strongly recalls possible prebiotic scenarios.
Samples containing J-aggregates formed by the porphyrin meso-tetrakis(4-sulfonatophenyl)porphine (H2TPPS44-) were studied a combination of elastic (ELS) and dynamic (DLS) light scattering techniques. Aggregation was fostered lowering pH increasing ionic strength (I; selected experimental conditions: (i) = 0.7; (ii) 2.8, I 0.5 M; (iii) 0.7, 2 M). The ELS data suggest presence self-similar structures, whose fractal dimension are df 1.7, 2.13, 2.09 (for case i, ii, iii, respectively). DLS...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTTemplate-Imprinted Chiral Porphyrin AggregatesEmanuele Bellacchio, Rosaria Lauceri, Sergio Gurrieri, Luigi Monsù Scolaro, Andrea Romeo, and Roberto PurrelloView Author Information Dipartimento di Scienze Chimiche Università Catania, Viale Doria 6 95125 Italy Istituto per lo Studio delle Sostanze Naturali Interesse Alimentare e Chimico Farmaceutico C.N.R., Chimica Inorganica Analitica Fisica Messina, ICTPN-C.N.R. Sezione Cite this: J. Am....
The anionic nickel(II) porphyrin NiTPPS is able to selectively sense the spermine induced left-handed Z-form of DNA while it completely silent in presence right-handed B-DNA. Interactions between and can be easily modulated by pH temperature. resulting Z-DNA−porphyrin−spermine complex behaves as a supramolecular reversible information storage system AND logic gate.
Z for zinc and Z-DNA: As a result of different binding modes, cationic porphyrin discriminates between B conformations DNA holds promise as probe Z-DNA. A very intense induced circular dichroism (ICD) effect with bisignate spectrum is observed upon interaction the Z-DNA (see graphic; red, green), whereas only weak ICD results its B-DNA.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUVRR spectroscopy of the peptide bond. 1. Amide S, a nonhelical structure marker, is C.alpha.H bending modeYang Wang, Roberto Purrello, Trace Jordan, and Thomas G. SpiroCite this: J. Am. Chem. Soc. 1991, 113, 17, 6359–6368Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August 1991https://pubs.acs.org/doi/10.1021/ja00017a002https://doi.org/10.1021/ja00017a002research-articleACS...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUVRR spectroscopy of the peptide bond. 2. Carbonyl H-bond effects on ground- and excited-state structures N-methylacetamideYang Wang, Roberto Purrello, Savas Georgiou, Thomas G. SpiroCite this: J. Am. Chem. Soc. 1991, 113, 17, 6368–6377Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August 1991https://pubs.acs.org/doi/10.1021/ja00017a003https://doi.org/10.1021/ja00017a003research-articleACS...
J-Aggregate antworten dynamisch auf durch Rühren erzeugte Strudel. Das CD-Signal kehrt sich mit der Rührrichtung um, und seine Intensität nimmt zu. Bei längerem lagern chirale Aggregate an Küvettenwand ab, deren Chiraliät von abhängt. verschiebt das Gleichgewicht einer racemischen Mischung zu die gewählten (und bevorzugten) Seite (siehe Bild; CW,CCW: im bzw. gegen den Uhrzeiger). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents...
The synthesis, characterization, optical, and fluorescent properties of an amphiphilic Schiff-base bis(salicylaldiminato)zinc(II) complex are reported. Detailed (1)H nuclear magnetic resonance (NMR), diffusion-ordered spectroscopy (DOSY) NMR, optical absorption, fluorescence studies indicate the existence aggregate species in noncoordinating solvents. degree type aggregation related to concentration polarity solvent. Dilute solutions likely characterized by presence defined dimers, whereas...
Self-organization is the driving force that led to evolution of life. Rationalization spontaneous self-assembly paradigm will offer tremendous potentialities obtain a wide variety complex systems, having specific functionality and properties. Herein, we propose an overview developments in non-covalent syntheses multi-porphyrin supramolecular species aqueous solution. This work took inspiration from pioneering studies aimed at rationalizing aggregation processes, governed by conventional...
ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTChiral H- and J-Type Aggregates of meso-Tetrakis(4-sulfonatophenyl)porphine on α-Helical Polyglutamic Acid Induced by Cationic PorphyrinsRoberto Purrello, Luigi Monsu' Scolaro, Emanuele Bellacchio, Sergio Gurrieri, Andrea RomeoView Author Information Dipartimento di Scienze Chimiche, Università Catania, Viale A. Doria 6, 95125, Italy, Chimica Inorganica, Analitica e Fisica, Messina, ICTPN CNR Sezione Istituto per lo Studio delle Sostanze Naturali...
Exploitation of the remarkable kinetic inertness and ability chiral aggregates built with opposite charged porphyrins to self-replicate leads a system able cycle between an "achiral" state.
Abstract The interaction between the tetra‐anionic porphyrin H 2 TPPS and its copper derivative, CuTPPS, with tetra‐cationic T4 CuT4, leads, in aqueous solution, to formation of remarkably stable kinetically inert heteroaggregates. aggregation process is under hierarchic control and, presence a suitable chiral mold, leads heteroassemblies as achiral ones. Because these properties, chirality “imprinted” heteroaggregates not only survives disruption template, but also complete removal from...
A designed amphiphilic Schiff-base bis(salicylaldiminato)zinc(II) complex, 1, forms defined aggregates in dilute solutions of non-coordinating solvents. The switching to the monomer can be driven by addition a coordinating species and involves dramatic enhancement fluorescence emission.
The aim of this study is to verify if water-soluble porphyrins can be used as proteasome inhibitors. We have found that cationic inhibit peptidase activities much more effectively than the corresponding anionic derivatives. relevance electrostatics in driving porphyin-proteasome interactions has been confirmed by observation inhibitory efficiency macrocycles decreases with number positive substituents. also investigated various metalloporphyrins, which differ due different propension central...
Anions do make a difference! Counterions released during the acid-promoted self-assembly of AB-type monomer precursors dock into designated ancillary binding sites and thus facilitate polymerization process while transferring their molecular properties to entire supramolecular structure (see picture). Detailed facts importance specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors....
The design of functional chiral nanostructures in aqueous solution represents one the most exciting challenges supramolecular chemistry, offering potential applications catalysis, sensing, and materials science. In this...
Journal of Porphyrins and PhthalocyaninesAccepted Papers Free AccessTuning hybrid porphyrin-melanin films via supramolecular approachAndrea Vella, Tiziano Grillo, Matteo Barcellona, Gabriele Travagliante, Maria E. Fragala, Roberto Purrello, Massimiliano Gaeta, Alessandro D'ursoAndrea Grillo Search for more papers by this author , Barcellona Travagliante Fragala Purrello Gaeta D'urso https://doi.org/10.1142/S1088424625500336Cited by:0 (Source: Crossref) PreviousNext...
Porphyrins are highly conjugated macrocyclic compounds that possess exceptional photophysical and chemical properties, progressively establishing themselves as versatile tools in the structural investigation of biomolecules. This review explores their role chiroptical conformational probes, focusing on interactions with DNA RNA. The planar electron rich structure porphyrin macrocycle promote π–π interactions, easy functionalization at meso positions, capacity to coordinate metal ions enable...
In this paper we investigate the self-aggregation of tetracationic porphyrin meso-tetrakis(N-methylpyridinium-4-yl)porphinatocopper(II) (CuT4) onto a chiral polymeric matrix (polyglutamic acid, PG) as well mixtures and tetraanionic, meso-tetrakis(4-sulfonatophenyl)porphine (H4TPPS), porphyrins same PG function pH, temperature, ionic strength, reactant concentration. The systems have been studied by light absorption, fluorescence, circular dichroism (CD), resonance scattering techniques....
The tetraanionic meso-tetrakis(4-sulfonatophenyl)porphine (H2TPPS) in the pH range 5−12 exists a monomeric form, and its fluorescence is not pH-dependent. However, presence of polylysine, absorption, circular dichroism, resonance light scattering data indicate extensive polymer-induced self-aggregation porphyrins. In addition, intensity vs behavior deeply modified, showing sigmoidal profile. particular, at low pHs (≤7), protonated polylysine promotes porphyrins binding with consequent strong...
In aqueous solution meso-tetrakis(4-phosphonatophenyl)porphyrin shows self-aggregation processes controlled by the "sergeant−soldier rule". After partial protonation of external phosphonic groups, it is possible (i) to further protonate inner nitrogen atoms molecules or (ii) allow, over time, system aggregate. Therefore, two procedure lead a different evolution, producing species with chemico-physical properties.