A5039015623- Cancer-related molecular mechanisms research
- DNA Repair Mechanisms
- Autism Spectrum Disorder Research
- Adipose Tissue and Metabolism
- Bone Metabolism and Diseases
- MicroRNA in disease regulation
- Macrophage Migration Inhibitory Factor
- RNA modifications and cancer
- Bone and Dental Protein Studies
- Estrogen and related hormone effects
- Vitamin D Research Studies
- Diabetes and associated disorders
- Bone health and osteoporosis research
- Genomics, phytochemicals, and oxidative stress
- Asthma and respiratory diseases
- Curcumin's Biomedical Applications
- Immune Response and Inflammation
- Eicosanoids and Hypertension Pharmacology
- Genetic factors in colorectal cancer
- Neuroinflammation and Neurodegeneration Mechanisms
- Psoriasis: Treatment and Pathogenesis
- Birth, Development, and Health
- Sepsis Diagnosis and Treatment
- PARP inhibition in cancer therapy
- Apelin-related biomedical research
Taif University
2014-2024
Zagazig University
2009-2019
Université de Montréal
2012
Zinc oxide nanoparticles (ZnONPs) are widely used in the last decades. Therefore, investigation of its neurotoxic effect is important. This work aimed to investigate potential adverse effects ZnONPs on rat's cerebellar cortex and possible neuroprotective role curcumin (Cur). Forty male albino rats were randomly divided into four equal groups. Two groups injected with one group was previously received Cur before ZnONPs. At end experiment, tissue samples prepared for histological,...
Although genetics plays an essential role in the pathogenesis of vitiligo, vitiligo is still unclear. Our aim was to investigate IFN-γ expression and polymorphism susceptibility whether intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor (TNF)-α, TNF-β play a as important inflammatory parameters. Eighty-five patients with 90 controls were investigated for gene by quantitative real-time PCR genotyped +874T/A (rs2430561) +2109A/G (rs1861494) polymorphisms sequence-specific primer...
Abstract Background Previous studies have suggested a strong genetic effect on sepsis pathogenesis. The present study aimed to investigate the role of miRNA‐146‐a expression in pediatric sepsis. Methods included 55 patients and 60 control children same age sex. Serum was measured using quantitative real‐time polymerase chain reaction. C‐reactive protein, interleukin‐6, tumor necrosis factor‐α procalcitonin levels were by an enzyme‐linked immunosorbent assay. outcome group determined at 28...
Interferon (IFN)-β is one of the disease modifying drugs used in treatment multiple sclerosis. A predictive marker that indicates good or poor response to highly desirable. We aimed investigate relation between immune genes receptors (IFNAR1, IFNAR2, and CCR5) expression their polymorhic variants sclerosis (MS) susceptibility as well IFN-β therapy. The genotyping were analyzed 80 patients with MS, treated 110 healthy controls. There was a significant decrease IFNAR1 IFNAR2 mRNA increase CCR5...