A5057675458- Building Energy and Comfort Optimization
- Urban Heat Island Mitigation
- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurosurgical Procedures and Complications
- Trigeminal Neuralgia and Treatments
- Imbalanced Data Classification Techniques
- Meningioma and schwannoma management
- Intracranial Aneurysms: Treatment and Complications
- Financial Distress and Bankruptcy Prediction
- Cancer-related molecular mechanisms research
- Trace Elements in Health
- Stock Market Forecasting Methods
- Glioma Diagnosis and Treatment
- Heavy Metal Exposure and Toxicity
- Noise Effects and Management
- Advanced Decision-Making Techniques
- Pharmacogenetics and Drug Metabolism
- Intracerebral and Subarachnoid Hemorrhage Research
- Conservation Techniques and Studies
- Organizational Learning and Leadership
- Spinal Hematomas and Complications
- Human Resource Development and Performance Evaluation
- RNA modifications and cancer
- Machine Learning in Healthcare
Columbia University
2024
University of Nottingham Ningbo China
2023
Zhejiang University
2023
Nanchang University
2007-2021
Union Hospital
2020-2021
Huazhong University of Science and Technology
2005-2021
Second Affiliated Hospital of Nanchang University
2020-2021
ORCID
2020
Union Hospital
2020
University of Tennessee Health Science Center
2019
Glioma stem cells (GSC) are a subpopulation of tumor with special abilities to proliferate and differentiate in gliomas. They one the main causes recurrence, especially under hypoxic conditions. Although long noncoding RNAs (lncRNA) known be involved numerous biological processes implied occurrence certain diseases, their role development progression remains poorly understood. Here we explored mechanisms by which lncRNA derived from GSCs (H-GSC) cause glioma progression. Isolation...
Pneumonia is a common complication after stroke, causing an increased length of hospital stay and death. Therefore, the timely accurate prediction post-stroke pneumonia would be highly valuable in clinical practice. Previous risk score models were often built on simple statistical methods such as logistic regression. This study aims to investigate using more advanced machine learning algorithms, specifically deep approaches.Using hospital's electronic health record(EHR) data from 2007-2017,...
In this paper, deep learning technology, along with a Gated Recurrent Unit (GRU) combined an attention mechanism, is used to enhance the recognition ability and risk assessment accuracy of abnormal trading behavior in financial markets. The GRU effectively solves problem gradient vanishing traditional recurrent neural networks through its unique gated structure, allowing model learn more stable effective feature representations long sequence data. On basis, contextual (CA) module mechanism...
In this study, BRL 3A cells were treated with different Cd concentrations (0, 10, 20, and 40 μmol/L) for 12 h preincubated or without N-acetyl-L-cysteine (NAC) (2 mmol/L) 30 min, (0 20 μmol/L), pretreated p38 inhibitor (SB203580), JNK (c-Jun NH2-terminal kinases) (SP600125), extracellular signal-regulated kinase (ERK) (U0126) then μmol/L h. decreased cell viability, SOD, GSH-Px activity in a concentration-dependent manner. Increased MDA level, ROS generation, nuclear condensation, shrinkage,...
Prediction of outcome for surgical patients with primary pontine hemorrhage (PPH) is seldom reported although many predictors from clinical and radiological features have been identified in conservative patients. The purpose this study was to assess the prognostic factors affecting 30-day mortality 3-month functional after PPH.Forty-five large PPH ( > 5 ml) Glasgow Coma Scale (GCS) score < 8 were treated surgically at West China Hospital. demographic, clinical, imaging follow-up data...
Abstract Background Glioma is a primary malignancy of the central nervous system (CNS). As biomedicine advances, an efficient molecular target urgently needed for diagnosis and treatment glioma. Meanwhile, several studies have demonstrated that glioma development closely related to immunity. PARP9 inactive mono‐ADP‐ribosyltransferase belonging poly‐ADP ribosyltransferase (ARTD) family. In this article, we aimed reveal relationship between explore potential prognostic value immunotherapeutic...
Malignant intraventricular meningiomas are quite rare and may spread along the craniospinal axis or extraneurally. However, simultaneous cerebrospinal dissemination distal extraneural metastasis has seldom been reported. A 51-year-old woman presented with recurrent anaplastic meningioma in trigone of right lateral ventricle over a 1.5-year period. Suggested radiotherapy was refused after each operation. The patient showed local relapse around previous tumoral cavity spinal canal during last...
The aims of the present study were to investigate effect cadmium (Cd)‑induced apoptosis and determine protective N‑acetylcysteine (NAC) in BRL 3A cells. cells treated with 0, 10, 20 or 40 µmol/l acetate (CdAc2) for 12 h. Another two groups preincubated 2 mmol/l NAC 30 min, then either incubated CdAc2 h, alone. levels mitochondrial membrane potential (ΔΨm) measured using flow cytometry. Mitochondrial ultrastructural changes detected transmission electron microscopy. protein caspase‑3,...
The aim of this study is to report the burden ocular morbidity following iodine-125 episcleral plaque brachytherapy (EPBT) in treatment American Joint Committee on Cancer (AJCC) T4-staged posterior uveal melanoma (PUM).Clinical records patients with PUM treated 125I EPBT were analyzed for incidence failure and radiation-induced complications.Cumulative local was 9% (95% CI 5-15%) at 5 years associated decreased tumor height (HR = 0.78; p 0.01). Cumulative enucleation 21% correlated worsening...
Background: Vertebrobasilar dolichoectasia (VBD) is one of the rare causes trigeminal neuralgia (TN). The common surgical treatments for patients with TN caused by VBD (VBD-TN) are microvascular decompression (MVD) and Gamma Knife radiosurgery (GKRS). However, therapeutic effects two methods have not been clinically compared, so this study was performed to evaluate treatment outcomes MVD GKRS VBD-TN. Methods: retrospective from March 2011 2019 in Wuhan Union Hospital. A total 80 diagnosed...
Background: Chemotherapy with or without pelvic radiotherapy (RT) is included in the NCCN Clinical Practice Guidelines Oncology (NCCN Guidelines) for metastatic anal cancer (MAC), despite limited clinical evidence RT this setting. In addition, increasing shows that local therapies, including RT, may increase patient survival some types of cancers. The purpose study was to evaluate patterns care and association between definitive overall (OS) patients MAC. Methods: National Cancer Database...
Intracranial epidermoid cysts are usually located in the paramedian regions with characteristic imaging features. Intracystic hemorrhage is rarely reported most cerebellopontine angle area. We described a case of hemorrhagic cyst cerebellar vermis. The patient was 21-year-old male presenting first episode convulsive seizure attack as initial and sole symptom. Head computed tomography showed mass lesion vermis high density nodular low back lesion. Magnetic resonance revealed hypointense to...
Background: RNA methylation modification is not only intimately interrelated with cancer development and progression but also actively influences immune cell infiltration in the tumor microenvironment (TME). genes influence therapeutic of lung adenocarcinoma (LUAD), mining prognosis-related markers LUAD crucial for its precise prognosis. Methods: RNA-Seq data Gene sets were collected from online databases or published literature. Genomic variation analysis was conducted by Maftools package....