A5100602331- Hydrology and Watershed Management Studies
- Flood Risk Assessment and Management
- Plant-Microbe Interactions and Immunity
- Cancer-related Molecular Pathways
- Plant Molecular Biology Research
- Ubiquitin and proteasome pathways
- Plant Pathogens and Fungal Diseases
- Endometrial and Cervical Cancer Treatments
- Photosynthetic Processes and Mechanisms
- Environmental and Agricultural Sciences
- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Analysis
- Thermochemical Biomass Conversion Processes
- Epigenetics and DNA Methylation
- Coal and Its By-products
- Hepatitis B Virus Studies
- Fungal Biology and Applications
- Ginseng Biological Effects and Applications
- Hydrology and Drought Analysis
- Gut microbiota and health
- Radiomics and Machine Learning in Medical Imaging
- Hepatitis C virus research
- Plant Stress Responses and Tolerance
- Microtubule and mitosis dynamics
- Medicinal Plants and Bioactive Compounds
Taiyuan University of Technology
2022-2024
First Affiliated Hospital of Wannan Medical College
2023-2024
Zhengzhou University of Light Industry
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Guilin Medical University
2024
Ministry of Agriculture and Rural Affairs
2022-2024
Beihua University
2024
Wannan Medical College
2023-2024
Viva Biotech (China)
2024
Epizyme (United States)
2024
p27$^{Kip1}$ (p27) is an intrinsically disordered protein (IDP) that folds upon binding to cyclin-dependent kinase (Cdk)$/$cyclin complexes (e.g., Cdk2$/$cyclin A), inhibiting their catalytic activity and causing cell cycle arrest. However, division progresses when stably A-bound p27 phosphorylated on one or two structurally occluded tyrosine residues $[$tyrosines 88 (Y88) 74 (Y74)$]$ a distal threonine residue $[$threonine 187 (T187)$]$. These events trigger ubiquitination degradation of...
Background/Aims: Golgi phosphoprotein 3 (GOLPH3) is a newly reported oncogene that plays significant role in regulating cell growth. Recent research has shown overexpression of GOLPH3 correlated with patient survival and M classification breast cancer other cancers. However, the mechanisms by which contributes to metastasis non-small lung (NSCLC) have not been previously clarified are therefore focus this work. Methods: Immunohistochemistry (IHC) western blotting analysis were performed...
In C4 plants, pyruvate orthophosphate dikinase (PPDK) activity is tightly dark/light regulated by reversible phosphorylation of an active-site threonine (Thr) residue; this process catalyzed PPDK regulatory protein (PDRP). Phosphorylation and dephosphorylation lead to its inactivation activation, respectively. Here, we show that light intensity rather than the light/dark transition regulates modulating at Thr-527 (previously termed Thr-456) in maize (Zea mays). The amount (unphosphorylated)...
This cohort study investigates overall survival among patients with newly diagnosed metastatic cervical cancer who received chemotherapy alone compared those and pelvic radiation therapy.
Atractylodes lancea is an important medicinal plant in traditional Chinese medicine, its rhizome rich of volatile secondary metabolites with values and largely demanded modern markets. Currently, supply high-yield, high-quality A. mainly achieved via cultivation. Certain soil microbes can benefit growth, metabolism induce resistance to environmental stresses. Hence, studies on the effects microbe communities isolates microorganisms extremely meaningful for future application Here we...
Atractylodes lancea is a medicinal plant widely used in treating rheumatic diseases, digestive disorders, night blindness, and influenza. Microbes greatly impact growth metabolism. However, the microbiome associated with A. remains unclear. Hence, we aimed at assessing effect of soil microbe inoculation on under heat stress from multiple perspectives, including regulation growth, valuable secondary metabolites, root endophytic rhizosphere bacterial communities. was inoculated microbes, then...
Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection and its treatment remains one foremost public health problems in world. The present study was performed order to investigate anti-HBV activity lutein vitro. antiviral examined by detecting levels HBsAg, HBeAg extracellular HBV DNA stable HBV-producing human hepatoblastoma HepG2 2.2.15 cells. It found that effectively suppressed secretion HBsAg from cells a dose-dependent manner, it also amount DNA. A...
Atractylodes lancea is widely distributed in East Asia, ranging from Amur to south-central China. The rhizome of A. commonly used traditional Chinese medicine, however, the quality products varies across different regions with geochemical characteristics.This study aimed identify chemotypes areas and screen for chemical markers by quantifying volatile organic compounds (VOCs) using a targeted metabolomics approach based on GC-MS/MS.The Hubei, Anhui, Shaanxi, region west Henan province was...
To investigate and compare the contrast-enhanced ultrasound (CEUS) features of histologically proven HCA with those computed tomography (CECT).Eighteen patients hepatic adenoma by pathology were retrospectively selected from CEUS database. Fourteen them had undergone liver CECT exams. The basic on unenhanced imaging enhancement level specific analyzed, differences between compared.All HCAs showed hyper-enhancement in arterial phase. During portal late phases, 12 (12/18, 66.7 %) 11 (11/14,...