A5100722131- Plant Stress Responses and Tolerance
- Rice Cultivation and Yield Improvement
- Photosynthetic Processes and Mechanisms
- Cervical Cancer and HPV Research
- Plant Micronutrient Interactions and Effects
- Prenatal Screening and Diagnostics
- Fetal and Pediatric Neurological Disorders
- Hepatitis B Virus Studies
- Bone fractures and treatments
- Seed Germination and Physiology
- Plant Molecular Biology Research
- Mitochondrial Function and Pathology
- Enzyme Structure and Function
- Circadian rhythm and melatonin
- Aluminum toxicity and tolerance in plants and animals
- Genomic variations and chromosomal abnormalities
- Gastric Cancer Management and Outcomes
- Animal Disease Management and Epidemiology
- Neural dynamics and brain function
- Protease and Inhibitor Mechanisms
- Bone and Dental Protein Studies
- Hepatitis Viruses Studies and Epidemiology
- Retinoids in leukemia and cellular processes
- Visual Attention and Saliency Detection
- Infrared Thermography in Medicine
Shihezi University
2025
Xinjiang Production and Construction Corps
2025
New York University
2023-2024
University of Science and Technology of China
2023-2024
Key Laboratory of Guangdong Province
2024
Rice Research Institute
2022-2024
Guangdong Academy of Agricultural Sciences
2022-2024
Changsha Hospital for Maternal and Child Health Care
2024
Inner Mongolia Medical University
2020-2024
Ministry of Agriculture and Rural Affairs
2024
Since the discovery of cell-free DNA (cfDNA) in maternal plasma, it has opened up new approaches for non-invasive prenatal testing. With development whole-genome sequencing, small subchromosomal deletions and duplications could be found by NIPT. This study is to review efficacy NIPT as a screening test aneuploidies CNVs 42,910 single pregnancies.A total pregnancies with different clinical features were recruited. The fetal was directly sequenced. Each chromosome...
In C4 plants, pyruvate orthophosphate dikinase (PPDK) activity is tightly dark/light regulated by reversible phosphorylation of an active-site threonine (Thr) residue; this process catalyzed PPDK regulatory protein (PDRP). Phosphorylation and dephosphorylation lead to its inactivation activation, respectively. Here, we show that light intensity rather than the light/dark transition regulates modulating at Thr-527 (previously termed Thr-456) in maize (Zea mays). The amount (unphosphorylated)...
Grapevines in cold regions are prone to frost damage winter. Due its adverse effects on soil structure, plant damage, high operational costs, and limited mechanization feasibility, buried overwintering has been gradually replaced by no-burial techniques, which now the primary focus for mitigating wine grapes. While current research focuses selection of thermal insulation materials, less attention paid mechanism covering materials methods. In this study, we investigated performance two...
Aim: To evaluate the clinical performance of PAX1 methylation (PAX1m) and cytology for patients with non-HPV16/18 high-risk HPV (hrHPV) infection. Methods: Cervical exfoliated cells from 387 outpatients hrHPV - positive were collected PAX1m assays. Results: The level increased severity histopathology. For cervical intraepithelial neoplasia (CIN)CIN2+/CIN3+, areas under curve both 0.87. specificity predictive value (PPV) greater than abnormal (CIN2+ specificity: 75.5 vs 24.8%; PPV: 38.8...
Abstract Background Breast cancer is one of the most common malignancies occurred in female around globe. Recent studies have revealed crucial characters miRNA and genes, as well essential roles epigenetic regulation breast initiation progression. In our previous study, miR-142-3p was identified a tumor suppressor led to G2/M arrest through targeting CDC25C. However, specific mechanism still uncertain. Methods We PAX5 upstream regulator miR-142-5p/3p ALGGEN website verified by series assays...
During orthodontic tooth movement, bone resorption occurs at the compression site. However, mechanism underlying remains unclear. Applying compressive force to human osteoblast-like cells grown in a 3D collagen gel, we examined gene induction by using microarray and RT-PCR analysis. Among 43 genes exhibiting significant changes, cyclo-oxygenase-2, ornithine decarboxylase, matrix metalloproteinase-3 (MMP-3) were up-regulated, whereas membrane-bound interleukin-1 receptor accessory protein was...
In Neurospora crassa, the methionine synthase gene met-8 plays a key role in synthesis. this study, we found that MET-8 protein levels were compromised several mutants defective proper heterochromatin formation. Bioinformatics analysis revealed 50-kb AT-rich region adjacent to promoter. ChIP assays confirmed trimethylated H3K9 was enriched region, indicating may form upstream of met-8. an H3K9R mutant strain, output dramatically reduced, similar what observed strains had Furthermore,...
Objective: Pyrotinib, a new irreversible dual pan-human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitor blocking EGFR and HER2, has achieved promising efficacy for advanced HER2-positive (HER2+) breast cancer. This study intended to further investigate the safety of neoadjuvant pyrotinib trastuzumab plus chemotherapy HER2+ cancer treatment. Methods: Thirty-eight patients who received (docetaxel carboplatin) were retrospectively reviewed. Clinical response by Response...
The dynamic buckling of liquid-filled shells is reviewed. Comparison the analysis with experimental results presented. governing equations imperfect are then derived. A simple imperfection pattern chosen to explain additional modes encountered in experiments.
Background. To determinate the association relationship of breast cancer bone metastasis and characteristics molecular subtype. Furthermore, to evaluate impact subtype on prevalence prognosis from base a large population real-word program, Surveillance, Epidemiology, End Results (SEER) database. Methods. We collected analyzed data obtained SEER, which showed information for each patient. The outcome in were estimated as per different subtypes. Results. Occurrence conformity with four...
Rice, a staple crop for nearly half the planet’s population, tends to absorb and accumulate excessive cadmium (Cd) when grown in Cd-contaminated fields. Low levels of Cd can degrade quality rice grains, while high inhibit growth plants. There is genotypic diversity distribution tolerance different varieties, but their underlying genetic mechanisms are far from elucidated, which hinders improvements. In this study, joint study phenotypic investigation with quantitative trait loci (QTLs)...
Rice (Oryza sativa L.) is a major staple food that provides not only dietary calories but also trace elements for the global inhabitants. The insufficiency of mineral nutrients and potential accumulation excessive toxic in grains pose risks to human health. substantial natural variations rice presents potentials genetic improvements via biofortifications essential eliminations grains. However, mechanisms underlying have been fully explored date owing unstable phenotypic variations, which are...
Abstract Objective. Distributed hypothalamic-midbrain neural circuits help orchestrate complex behavioral responses during social interactions. Given rapid advances in optical imaging, it is a fundamental question how population-averaged activity measured by multi-fiber photometry (MFP) for calcium fluorescence signals correlates with behaviors question. This paper aims to investigate the correspondence between MFP data and behaviors. Approach: We propose state-space analysis framework...
Temperature is an important environmental factor affecting heading date of rice. Despite its importance, genes responsible for temperature-sensitive in rice have remained elusive. Our previous study identified a quantitative trait locus qHd1 which advances under high temperatures. A 9.5-kb insertion was found the first intron OsMADS51 indica variety Zhenshan 97 (ZS97). However, function this natural variant controlling temperature sensitivity has not been verified. In study, we used...
Auditory spatial attention detection (ASAD) aims to determine which speaker in a surround sound field listener is focusing on from single-trial electroencephalogram (EEG). Latest studies have represented non-Euclidean structured EEGs by graph-based modeling, but how better incorporate brain connectivity into EEG graphs remains great challenge. Moreover, due inter-subject distribution shifts EEGs, most existing models perform well only specific subjects. To address these issues, we propose...
Rice phosphatidylcholine transfer protein (PCTP), which contains a steroidogenic acute regulatory protein-related lipid (START) domain, responds to bacterial blight disease. Overexpression of OsPCTP quantitatively enhances resistance pathogen in rice, whereas depletion it has the opposite effect. Further analysis showed that physically interacts with OsAPX8, ROS scavenging enzyme, and influences ascorbate peroxidase enzymatic activity vivo. In addition, expression pathogenesis-related genes...
Myeloid sarcoma (MS) is a rare extramedullary tumor originating from immature bone marrow cells. MS of the breast an extremely uncommon disease with non-specific clinical and radiological features. The present case report describes distinctive breast, which posed diagnostic challenges due to absence typical imaging characteristics at time presentation. patient was 58-year-old woman who presented mass. Further examination testing confirmed diagnosis in right metastases iliac, pubic ischial...
Objective This study aimed to evaluate the clinical utility of PAX1/JAM3 methylation (CISCER) test in triaging high-risk human papillomavirus (hrHPV)-positive women. Methods We enrolled women who underwent opportunistic screening at Cervical Disease outpatient clinics Xuzhou Maternity and Child Health Hospital, Yueyang Central Hospital from December 2022 May 2024. The effectiveness CISCER cytology tests hrHPV+ patients was analyzed. Results Among 436 participants, 283 (64.9%) had no cervical...