A5062207975- Computational Drug Discovery Methods
- Antimicrobial Peptides and Activities
- Biomedical Text Mining and Ontologies
- Genetics, Bioinformatics, and Biomedical Research
- Machine Learning in Bioinformatics
- E-Learning and Knowledge Management
- vaccines and immunoinformatics approaches
- Scientific Computing and Data Management
- Visual perception and processing mechanisms
- Biomedical and Engineering Education
- Research Data Management Practices
- Species Distribution and Climate Change
- Plant Parasitism and Resistance
- Insect-Plant Interactions and Control
- Protein Degradation and Inhibitors
- Ecology and Vegetation Dynamics Studies
- Chemical Synthesis and Analysis
- Plant and animal studies
- RNA and protein synthesis mechanisms
- Genomics and Phylogenetic Studies
- Semantic Web and Ontologies
- Plant-Microbe Interactions and Immunity
Maastricht University
2023-2025
Novo Nordisk Foundation
2025
Universidad San Francisco de Quito
2019-2023
The flowering phenology of many tropical mountain forest tree species remains poorly understood, including synchrony and its drivers across neotropical ecosystems. We obtained herbarium records for 427 from a long-term monitoring transect on the northwestern Ecuadorian Andes, sourced Global Biodiversity Information Facility Herbario Nacional del Ecuador. Using machine learning algorithms, we identified phenophases digitized specimen labels applied circular statistics to build phenological...
Motivation The analysis of omics data typically involves multiple bioinformatics tools and methods, each producing distinct output files. However, compiling these results into comprehensive reports often requires additional effort technical skills. This creates a barrier for non-bioinformaticians, limiting their ability to produce from findings. Moreover, the lack streamlined reporting workflows impacts reproducibility transparency, making it difficult communicate track analytical processes....
Antimicrobial peptides (AMPs) are promising molecules to treat infectious diseases caused by multi-drug resistance pathogens, some types of cancer, and other conditions. Computer-aided strategies efficient tools for the high-throughput screening AMPs.This report highlights StarPep Toolbox, an open-source user-friendly software study bioactive chemical space AMPs using complex network-based representations, clustering, similarity-searching models. The novelty this research lies in combination...
Antimicrobial peptides (AMPs) have appeared as promising compounds to treat a wide range of diseases. Their clinical potentialities reside in the mechanisms they can use for both killing microbes and modulating immune responses. However, hugeness AMPs' chemical space (AMPCS), represented by more than 10
<ns4:p>Since 2014, the ISCB Latin American Student Council Symposium (LA-SCS) serves as main biannual activity where students from all levels, postdocs and early researchers entire region can gather to discuss recent advances in fields of bioinformatics computational biology. This time we faced a major unexpected obstacle, worldwide pandemic that has completely disrupted human activities at planetary scale. Countless conferences have been either canceled, reprogrammed for next year or moved...
<ns4:p>Since 2004, the ISCB Student Council has been organizing different symposia worldwide, gathering together community of young computational biologists. Due to coronavirus disease 2019 (COVID-19) pandemic situation, world scientific was forced cancel in-person meetings for almost two years, imposing adoption virtual formats instead. After successful editions our continental in 2020 USA, Latin America, and Europe, we organized flagship global event, Symposium (SCS) 2021, trying apply all...
The jasmonic acid (JA) signaling pathway is one of the primary mechanisms that allow plants to respond a variety biotic and abiotic stressors. Within this pathway, JAZ repressor proteins basic helix-loop-helix (bHLH) transcription factor MYC3 play critical role. JA volatile organic compound with an essential role in plant immunity. increase concentration leads decoupling bHLH causing induction genes interest. goal study was identify molecular basis JAZ-MYC coupling. For purpose, we modeled...
Abstract Streptomyces clavuligerus is a Gram‐positive bacterium that high producer of secondary metabolites with industrial applications. The production antibiotics such as clavulanic acid or cephamycin has been extensively studied in this species; nevertheless, other aspects, evolution ecology, have received less attention. Furthermore, genes arise from ancient events lateral transfer demonstrated to be implicated important functions host species. This approximation discovered relevant...
Antimicrobial peptides (AMPs) are small bioactive chemicals that have appeared as promising compounds to treat a wide range of diseases. The effectiveness AMPs resides in the mechanisms they can use for both killing microbes and modulating immune responses. However, AMPs’ chemical space (AMPCS) is huge, it estimated there exist more than 1065 unique sequences with 50 residues or fewer, which represent big challenge discovery new identification common features, motifs, relevant biological...
Antimicrobial peptides (AMPs) are small bioactive chemicals that have appeared as promising compounds to treat a wide range of diseases. The effectiveness AMPs resides in the mechanisms they can use for both killing microbes and modulating immune responses. However, AMPs’ chemical space (AMPCS) is huge, it estimated there exist more than 1065 unique sequences with 50 residues or fewer, which represent big challenge discovery new identification common features, motifs, relevant biological...
Antimicrobial peptides (AMPs) have appeared as promising compounds to treat a wide range of diseases. Their clinical potentialities reside in the mechanisms they can use for both killing microbes and modulating immune responses. However, hugeness AMPs’ chemical space (AMPCS), represented by more than 1065 unique sequences 50 residues long or less, has big challenge discovery new identification common structural motifs even relevant biological functions. Here, we present approach based on...
<ns4:p>The COVID-19 pandemic profoundly changed how scientific conferences are</ns4:p><ns4:p> organized, fostering virtual meetings. These online events have allowed students</ns4:p><ns4:p> and researchers to overcome geographical, administrative economic barriers to</ns4:p><ns4:p> attend organize high-quality international symposiums. Moreover, these virtual</ns4:p><ns4:p> contributed the creation of inclusive activities that strengthen</ns4:p><ns4:p> communities. Here, we summarize main...