- Hormonal and reproductive studies
- Pharmacological Effects and Assays
- Animal health and immunology
- Microbial infections and disease research
- Metabolomics and Mass Spectrometry Studies
- Ruminant Nutrition and Digestive Physiology
- Veterinary Pharmacology and Anesthesia
- Herpesvirus Infections and Treatments
- Pesticide Residue Analysis and Safety
- Reproductive Physiology in Livestock
- Cardiovascular Conditions and Treatments
- Mass Spectrometry Techniques and Applications
- Analytical Chemistry and Chromatography
- Yersinia bacterium, plague, ectoparasites research
- Milk Quality and Mastitis in Dairy Cows
- Prion Diseases and Protein Misfolding
- Trace Elements in Health
- Entomological Studies and Ecology
- Actinomycetales infections and treatment
- Geotechnical and Geomechanical Engineering
- Infectious Diseases and Mycology
- Plant and fungal interactions
- Anesthesia and Sedative Agents
- Mycobacterium research and diagnosis
- Anesthesia and Pain Management
Oniris
1985-2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022
Centre Hospitalier Départemental Vendée
2018-2019
Laboratoire D'étude des Résidus et Contaminants Dans les Aliments
2015-2018
Roche (France)
2018
Université Nantes Angers Le Mans
2013-2017
Département Santé Animale
2011-2016
Nantes Université
2015
Biologie Epidémiologie et Analyse de Risque en santé animale
2014
École Nationale Vétérinaire de Toulouse
2006-2008
Abstract Caprine-like Generalized Hypoplasia Syndrome (SHGC) is an autosomal-recessive disorder in Montbéliarde cattle. Affected animals present a wide range of clinical features that include the following: delayed development with low birth weight, hind limb muscular hypoplasia, caprine-like thin head and partial coat depigmentation. Here we show SHGC caused by truncating mutation CEP250 gene encodes centrosomal protein C-Nap1. This results centrosome splitting, which neither affects...
Thyrostats have been banned for use as veterinary drugs in Europe since 1981 because of their carcinogenic and teratogenic properties. Until now, the identification thiouracil animal biological matrices has interpreted consequence an illegal administration. The present paper studies influence a cruciferous-based feed on occurrence residue urine. Urine samples collected from two heifers fed cabbage or rapeseed cakes were analysed presence by 3-iodobenzylbromide derivatization liquid...
Objective To describe a laparoscopic technique for evaluating umbilical disorders in calves, including feasibility, visualization of structures, and related complications. Study Design Prospective clinical study. Animals Male calves (15 Holstein, 2 Montbeliard) with (n=17). Methods Calves <2 months old obvious disease were assessed by examination ultrasonography the structures. Laparoscopic evaluation was performed dorsal recumbency under subarachnoid lumbosacral anesthesia sedation. An...
Abstract The use of anabolic steroids as growth promoters for meat‐producing animals is banned within the European Union. However, screening illegal natural steroid hormones still represents a difficult challenge because high interindividual and physiological variability endogenous concentration levels in animals. In this context, development untargeted profiling approaches identifying new relevant biomarkers exposure and/or effect has been emerging couple years. present study deals with an...
Currently under development for therapeutic purposes in human medicine, non‐steroidal selective androgen receptor modulators (non‐steroidal SARMs) are also known to impact growth associated pathways. As such, they present a potential abuse sports and food‐producing animals as interesting alternative anabolic substances. Forbidden since 2008 by the World Anti‐Doping Agency (WADA) these compounds however easily available could be (mis)used livestock production promoters. To prevent such...
Selective androgen receptor modulators (SARMs) are a novel class of ligands. They intended to exhibit the same kind effects as androgenic drugs, like anabolic steroids, but be much more selective in their action, targeting particular tissues without any undesirable on others. While main applications these synthetic substances for therapeutic purposes, they also have high potential misuse veterinary practice and sporting world. In order guarantee consumers with food from animal origin that it...
The use of anabolic agents in food-producing animals has been prohibited within the EU since 1988. control illegal natural steroid hormones cattle is still an exciting analytical challenge as no definitive method and nonambiguous criteria are available. We have used gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) to demonstrate administration cortisol cattle. consisted efficient combination between OASIS HLB solid-phase extraction (SPE), oxidation, SiOH SPE...
Besides their development for therapeutic purposes, non‐steroidal selective androgen receptor modulators (non‐steroidal SARMs) are also known to impact growth‐associated pathways as ligands of androgenic receptors (AR). They present a potential abuse in sports and food‐producing animals an interesting alternative anabolic steroids (AAS). These compounds easily available could therefore be (mis)used livestock production growth promoters. To prevent such practices, dedicated analytical...
Background: Recently, a progressive pelvic limb ataxia and paraparesis leading invariably to recumbency has been reported in Rouge‐des‐prés calves. Objectives: To characterize the clinical pathological findings of this newly disease investigate its potential causes. Animals: Nine calves from 7 different farms were prospectively studied initial diagnosis through postmortem examination. Methods: Physical neurological examinations, blood tests, cerebrospinal fluid (CSF) analysis, myelographic...
Actinobacillosis usually is a sporadic infection that affects the tongue in cattle (“wooden tongue”) with possible spread to digestive tract. Two 4‐year‐old Rouge‐des‐Prés cows from single French beef herd were referred for chronic (2‐6 months) swelling and cutaneous nodules distal hind limbs. In addition signs, physical examination disclosed cachexia, lameness, lymphadenitis of limbs, pneumonia both cows. Cytologic direct skin smears was inconclusive, no parasites observed multiple...
A case study of renal tubular dysfunction consistent with idiopathic Fanconi syndrome is reported in an 18‐month‐old Holstein heifer. The clinical, biochemical, and histopathological features are described. heifer had clinical signs growth retardation, wasting, persistent diarrhea. Biochemical blood analysis identified hypokalemia, hyponatremia, hypochloremia. Urinalysis glycosuria, proteinuria, acidic pH . Histological examination the kidney disclosed mild necrosis proteinaceous casts...
Nutritional deficiencies in mineral metabolism have been described or suspected managed and wild ungulate populations. In blesboks (Damaliscus pygargus phillipsi), clinical signs of copper the as well captivity. Plasma concentrations cobalt (Co), (Cu), iodine (I), manganese (Mn), selenium (Se), zinc (Zn) were measured over a 6-mon period by inductively coupled plasma mass spectrometry two groups five apparently healthy from single zoological collection. The control group did not receive any...