A5064767841- Restraint-Related Deaths
- Poisoning and overdose treatments
- Injury Epidemiology and Prevention
- Neurogenesis and neuroplasticity mechanisms
- Alcohol Consumption and Health Effects
- Forensic Toxicology and Drug Analysis
- Pesticide Exposure and Toxicity
- Automotive and Human Injury Biomechanics
- Cardiac Arrest and Resuscitation
- Traumatic Ocular and Foreign Body Injuries
- Stress Responses and Cortisol
- Alzheimer's disease research and treatments
- Pesticide Residue Analysis and Safety
- Carcinogens and Genotoxicity Assessment
- Heme Oxygenase-1 and Carbon Monoxide
- Neuroendocrine regulation and behavior
- Plant-based Medicinal Research
- Trauma Management and Diagnosis
- Obsessive-Compulsive Spectrum Disorders
- Forensic Entomology and Diptera Studies
- Cardiovascular and Diving-Related Complications
- Analytical Chemistry and Chromatography
- Ion channel regulation and function
- Muscle and Compartmental Disorders
- Travel-related health issues
Kawasaki Medical School
2018-2025
Japanese Red Cross Medical Center
2019
University of the Ryukyus
2006-2018
Okinawa Prefecture
2017
Toujinkai Hospital
2014
Okinawa Red Cross Hospital
2008
University of Ulster
2008
Altnagelvin Area Hospital
2008
University of the Ryukyus University Hospital
2008
Kitasato University
2008
Summary The goal of the present study was to investigate inter‐individual and age‐dependent variation global DNA methylation in human tissues. In this work, we examined 5‐methyldeoxycytidine ( met C) content by HPLC peripheral blood leukocytes obtained from 76 healthy individuals ages varying 4 94 years (yr), 39 placentas various gestational stages. analysis revealed a significant C across is consistent with previous findings decrease levels relatively small, but statistically highly p =...
Abstract Spontaneously hyperlipidaemic (Apoe shl ) mice were discovered in 1999 as lacking apolipoprotein E (ApoE) owing to a mutation the Apoe gene. However, age-related behavioural changes commercially available have not yet been clarified. The abnormalities of ApoE-deficient mice, which are genetically modified artificially deficient ApoE, investigated detail, and it has reported that they can serve model Alzheimer’s disease (AD). To understand whether also murine AD, is necessary...
A primary aortoenteric fistula (PAEF), defined as a communication between the native aorta and gastrointestinal tract, is rare cause of bleeding.The preoperative diagnosis PAEF extremely difficult.Consequently, may sudden unexpected death.We present an autopsy case 68-year-old man who died massive bleeding due to PAEF.Autopsy revealed pinhole rupture located on third part duodenal mucosa fistulized into adjacent abdominal aortic aneurysm (AAA).Our indicates that can result in fatal...
Various blood samples were collected from heart cavities and vessels in eight autopsy cases of people who had been methamphetamine abusers. Methamphetamine its metabolite, amphetamine, determined by gas chromatography-mass spectrometry-selected ion monitoring. In four where left right collected, concentrations the 1.9–2.6 times higher than those samples. three pulmonary vein other sites. To interpret concentrations, site dependence should be taken into consideration.
Simultaneous determination of oleandrin and its three related compounds, desacetyloleandrin, oleandrigenin, gitoxigenin in blood by using liquid chromatography-three-dimensional quadrupole mass spectrometry (LC-3DQMS) system equipped with sonic spray ionization (SSI) interface was conducted. This analyzing method suitable for all these compounds except gitoxigenin. The limits detection oleandrigenin desacetyloleandrin from were 2 ng/mL that 3 ng/mL. calibration curves oleandrin, linear the...
Uterine leiomyoma is the most common tumor in women of reproductive age, but rarely does it lead to fatal hemoperitoneum. We present an autopsy case which cause death was massive hemoperitoneum due rupture a subserosal vein overlying uterine leiomyoma. report 28-year-old Japanese woman who had tuberous sclerosis and gravida 0, para 0. She leading dysmenorrhea. Autopsy revealed pinhole-sized superficial that resulted Rupture may sudden unexpected death.
With increased life expectancy, age-related diseases are a significant health concern in Western societies. Animal models (e.g., rodents) have been used to understand changes brain function-particularly through the senescence-accelerated mouse (SAM) strain. Previous reports shown that propensity (SAMP)8 and SAMP10 strains learning disabilities. In this study, we analyzed prefrontal cortex, which is involved cognitive function. We aimed clarify parvalbumin-positive interneurons (PV-positive...