- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Essential Oils and Antimicrobial Activity
- Biofuel production and bioconversion
- Phytochemicals and Antioxidant Activities
- Fungal Biology and Applications
- Peptidase Inhibition and Analysis
- Plant Virus Research Studies
- Biochemical and biochemical processes
- Microbial Metabolism and Applications
- Ethnobotanical and Medicinal Plants Studies
- Genomics and Phylogenetic Studies
- Microbial bioremediation and biosurfactants
- Enzyme Production and Characterization
- Legume Nitrogen Fixing Symbiosis
- biodegradable polymer synthesis and properties
- Biochemical and Molecular Research
- Plant biochemistry and biosynthesis
- Phytochemistry and Biological Activities
- Histone Deacetylase Inhibitors Research
- Electrospun Nanofibers in Biomedical Applications
- Click Chemistry and Applications
- Natural Antidiabetic Agents Studies
- Natural product bioactivities and synthesis
- Bamboo properties and applications
Academy of Scientific and Innovative Research
2020-2025
Indian Institute of Integrative Medicine
2018-2025
Council of Scientific and Industrial Research
2023
Institute of Hydrobiology, Biology Centre, Academy of Sciences of the Czech Republic
2022
Czech Academy of Sciences
2022
Indian Institute of Technology Roorkee
2010-2014
Graphic Era University
2013
Mangalayatan University
2012
Antioxidant and antimicrobial activities of nutmeg (Myristica fragrans Houtt) seed extracts were evaluated. Seeds extracted with acetone, ethanol, methanol, butanol water. All the have shown significant antioxidant against tested microorganisms. Among all extracts, acetone extract has highest activity. The showed 93.12 ± 1.48 mg gallic acid equivalents (GAE)/100 g dry weight total phenolic content, DPPH scavenging activity 63.04 1.56%, chelating 64.11 2.21% 74.36 1.94% inhibition β-carotene...
Meloidogyne incognita (Root-knot nematode) and Alternaria alternata (fungus) were among the dominant parasites of medicinal plant Withania somnifera. Despite fatal nature their infection, a comprehensive study to explore evolution adaptation is lacking. The present elucidates evolutionary codon usage bias analysis W. somnifera (host plant), M. (root-knot A. (fungal parasite). results revealed weak prevalent in all three organisms. Based on nucleotide analysis, genome was found be A-T biased...
Natural value-added compounds produced from biological sources have attained immense significance in medicinal, food, flavourings, and agrochemical industries. Further, biotransformation is a powerful tool used to produce cost-effectively selectively. In the present study, of eugenol using an endophytic fungus Daldinia sp. IIIMF4010 isolated fresh leaves plant Rosmarinus officinalis leads production two known compounds. The reaction (50 mM) resulted eugenol-β-D-glucopyranoside (6.2%)...
Nitrile hydrolyzing moderate halophilic bacterium Halomonas sp. IIIMB2797 was isolated from Sambhar Lake, India. Maximum cell biomass and nitrilase production were observed at 60 g L-1 NaCl in the media which confirms its nature. Nitrilase of proved to be inducible nature as maximum activity when valeronitrile added media. Whole cells exhibited broad substrate affinity towards aromatic aliphatic nitriles. Optimum pH temperature for 7.0 45 °C, respectively. Effect salinity on also studied...
Presently, N‐hydroxy‐N′‐phenyloctanediamide (vorinostat) which is an effective histone deacetylase inhibitor, being synthesized chemically. Hence, present study aims to develop eco‐friendly approach for the synthesis of vorinostat from N′‐phenyloctanediamide through biotransformation. Using amidase Bacillus smithii IIIMB2907 in time course conversion and organic solvent compatibility, maximum bioconversion was observed at 12 h reaction presence ethanol, respectively. Potassium phosphate...
Microbial biotransformation is an efficient process for making high-value natural products in a controlled and environment friendly manner. Bioconversion of low value monoterpenes to high using fungi offers effective strategy producing desirable products. Efficient conversion D-limonene, monoterpene, into carveol reported this study by endophytic fungus, Aspergillus flavus IIIMF4012, isolated from the root Rosa damascena. By optimizing different parameters, strain resulted hydroxylation...
Nitrile metabolizing enzymes are of great industrial interest for the selective bio-transformation nitriles and surface modification synthetic polymers under mild reaction conditions. In present work, isolated strain Amycolatopsis sp. IITR215 was cultivated in bench top bioreactor recovery maximum biomass whole cell catalyst. Effect different lyoprotectants studied on nitrile enzyme from which sorbitol proved to be an efficient lyoprotectant. physical mechanical methods, only 30% activity...
Aim: The aim of the present study was to understand molecular relationship between nematode (parasite) and fish (host) through codon usage bias (CUB) analysis. Methodology: Codon analysis has been performed in Carassius gibelio (Prussian carp) parasite Anisakis simplex. complete coding sequences (CDS) C. A. simplex (Nematode) were retrieved from National Center for Biotechnology Information followed that we have bioinformatics pattern host parasite. Results: Different CUB indices like...
Till date, amidases from halophiles and halotolerant micro-organisms have not been much explored. In the present study, Brevibacterium sp. IIIMB2706 strain was isolated salt fields of Gujarat, India, using propionitrile as a nitrogen source in mineral base media explored for its amidase activity. Amidase exhibited substrate affinity towards isobutyramide, propionamide butyramide. The optimum temperature pH required maximum activity 45 °C 7.0, respectively. Effect concentration on also...