A5100330827- Nutrition and Health in Aging
- Air Quality and Health Impacts
- Liver Disease Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Rheumatoid Arthritis Research and Therapies
- Gut microbiota and health
- Frailty in Older Adults
- Dermatology and Skin Diseases
- Energy and Environment Impacts
- Cancer Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Spondyloarthritis Studies and Treatments
- Salivary Gland Disorders and Functions
- Immunodeficiency and Autoimmune Disorders
- Stroke Rehabilitation and Recovery
- Folate and B Vitamins Research
- Body Composition Measurement Techniques
- Urban Green Space and Health
- RNA modifications and cancer
- Cancer survivorship and care
- Microbial Community Ecology and Physiology
- Lymphatic System and Diseases
- Psoriasis: Treatment and Pathogenesis
- Neurological Disease Mechanisms and Treatments
- Dysphagia Assessment and Management
Academic Degrees & Graduate Education
2025
Institute of Hematology & Blood Diseases Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Peking Union Medical College Hospital
2024
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2022-2024
Institute for In Vitro Sciences
2024
Anhui Medical University
2022-2023
Suzhou Traditional Chinese Medicine Hospital
2023
Nanjing University of Chinese Medicine
2023
First Affiliated Hospital of Xinjiang Medical University
2021-2022
MVI has significant clinical value for treatment selection and prognosis evaluation in hepatocellular carcinoma (HCC). We aimed to construct a model based on MVI-Related Genes (MVIRGs) risk assessment prediction patients with HCC. This study utilized various statistical analysis methods prognostic construction validation the Cancer Genome Atlas (TCGA) International Consortium (ICGC) cohorts, respectively. In addition, immunohistochemistry qRT-PCR were used analyze identify of our cohort....
With the gradual improvement of living standards, incidence gallstones is getting higher and higher, cholesterol (CG) are most prevalent subtype. Therefore, we urgently need a better way to treat gallstones. This study aimed evaluate effects resveratrol (Res) on gallstone formation explore its underlying mechanisms, focusing modulation hepatic peroxisome proliferator-activated receptor γ (PPAR-γ) expression, bile saturation, metabolism. Thirty-two male C57BL/6 mice were randomly divided into...
Vascular diseases, including atherosclerosis, aneurysms, and vascular calcification, are a leading cause of morbidity mortality worldwide. In past decades, the gut microbiota has been found to be an indispensable population exerting effects on hosts under physiological pathological conditions. Gut microbiota-derived metabolites, such as trimethylamine-N-oxide short-chain fatty acids, mediate these by regulating cells systematically. Translation research knowledge clinical scenarios led...
More studies focus on reporting the effects of ambient air pollution physical activity while ignoring hazards indoor caused by household solid fuel use. Moreover, impact individual cognitive and depressive status health is often overlooked.We examined association between activities daily living (ADL) trajectories, further this in homogeneous subgroups or trajectories.Participants were from China Health Retirement Longitudinal Study, which conducted four waves surveys 2011 to 2018. We...
Because sarcopenia is widely distributed in patients with acute ischemic stroke (AIS) and has not attracted enough attention, this study aims to explore the relationship between defined by temporal muscle thickness (TMT) physical function prognosis of AIS. A total 265 hospitalized nonsurgical AIS from 2015 2018, an age range 28 ~ 92, were analyzed retrospectively. The median value TMT was used as risk classification index sarcopenia. main results Essen Stroke Risk Score, National Institutes...
Although Transartial chemoembolization (TACE) is one of the recommended treatments for hepatocellular carcinoma (HCC), there always a dispute on selection best beneficiary treatment. We studied prognostic value nutritional markers, obesity, visceral obesity and sarcopenia survival outcomes under single different combinations. In retrospective cohort 235 patients with HCC at stages, more accurate comprehensive factors were obtained by combining comparing multifactor hazard ratios (HR) various...
Interleukin-35 (IL-35) is a critical anti-inflammatory cytokine in autoimmune disease. In the current study, we aimed to investigate serum IL-35 levels and its clinical association patients with primary Sjögren's syndrome (pSS) whether or not participates pathogenesis of pSS. One hundred seventy-six pSS 60 healthy controls (HCs) were recruited. Disease activity was assessed according EULAR SS disease index. Serum quantified by enzyme-linked immunosorbent assay. The correlations between...
IL-35 was reported as a crucial anti-inflammatory cytokine and could efficiently regulate bone metabolism in murine collagen-induced arthritis model. However, the relationship between health human rheumatoid (RA) has not been clarified. In this study, aim to explore correlations loss postmenopausal women with RA.The study included 76 RA 53 healthy controls (HCs). Serum levels were detected by enzyme-linked immunosorbent assay. Bone mineral density (BMD) at lumbar spine 1-4 total hip measured...
Interleukin (IL)-35 is confirmed as an important modulator in immune response. The aim of the study was to explore role IL-35 development polymyositis/dermatomyositis (PM/DM). Ninety-five patients with PM/DM and 30 healthy controls (HCs) were recruited. Peripheral blood mononuclear cells (PBMCs) isolated by Ficoll-Paque Plus density gradient centrifugation. Protein IL-35, IL-17, tumor necrosis factor (TNF)-α levels measured using enzyme-linked immunosorbent assay method. serum significantly...
Iron regulatory protein 2 (IRP2) deficiency in mice and humans causes microcytic anemia neurodegeneration due to functional cellular iron depletion. Our previous vitro data have demonstrated that Irp2 depletion upregulates hypoxia-inducible factor subunits Hif1α Hif2α expression; inhibition of rescues ablation-induced mitochondrial dysfunction; suppresses the overdose production lactic acid derived from actively aerobic glycolysis. We wonder whether are also elevated vivo play a similar role...
Objective To explore the effects of mindfulness training combined with auricular acupressure on sleep quality and negative emotion in patients stroke. Methods Totally 70 stroke hospitalized Rehabilitation Department First Affiliated Hospital Harbin Medical University between October December 2018 were selected by convenient sampling, randomly divided into observation group (n=35) control . Patients received routine rehabilitation nursing, while this basis. The Pittsburgh Sleep Quality...
Air pollution causes 6.5 million deaths globally each year, with urban particulate matter (UPM) accounting for the largest share. UPM can pass rapidly into systemic circulation and persist a long time. However, whether may have any impact on blood components has been hardly studied. Here, standards (SRM1648a) were used to assess influence of erythrocyte quality in terms oxygen-carrying ability, energy metabolism, morphological changes, oxidative damage macrophage clearance. Results showed...
Abstract Background Depression is a serious public health problem today, especially in middle-aged and older adults. Although the etiology of disease has not been fully elucidated, environmental factors are increasingly negligible. Cadmium widely used industrial production. The general population may be chronically exposed to low doses cadmium. This study aimed investigate association between blood cadmium depression explore mediating role aging indicators this process. Methods We conducted...
Rope jumping is a popular sport and widely-used training tool among teenagers, adults professional athletes in China where its energy expenditure characteristics based on Chinese population haven't been published officially yet. PURPOSE: To determine compare exercise intensity (EI), (EE) excess post-exercise oxygen consumption (EPOC) between 3 different paces of rope using indirect calorimetry (IDC) heart rate (HR) monitor to estimate EE with HR. METHODS: 36 college students (F/M = 1/1, Age...