A5076152673- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Nanoparticles: synthesis and applications
- Advancements in Transdermal Drug Delivery
- Analytical Methods in Pharmaceuticals
- Inhalation and Respiratory Drug Delivery
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- Lipid Membrane Structure and Behavior
- MicroRNA in disease regulation
- Microencapsulation and Drying Processes
- Crystallography and molecular interactions
- Curcumin's Biomedical Applications
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- Liver Disease Diagnosis and Treatment
- Food Chemistry and Fat Analysis
- Pharmacology and Obesity Treatment
- Food Science and Nutritional Studies
- Polysaccharides Composition and Applications
Assiut University
2015-2024
Aswan University
2023
Mutah University
2018-2019
Liverpool John Moores University
2011-2014
Abstract The use of cellulosic polymers as efficient reducing, coating agents, and stabilizers in the formulation silver nanoparticles (AgNPs) with antioxidant antibacterial activity was investigated. AgNPs were synthesized using different polymers, polyethylene glycol, without tri-sodium citrate, for comparison. yield, morphology, size, charge, vitro release ion, physical stability resulting evaluated. Their measured a scavenging percentage compared ascorbic acid, while their evaluated...
Cancer is one of the leading causes death worldwide. In many cases, cancer related to elevated expression a significant cytokine known as tumor necrosis factor-α (TNF-α). Breast in particular linked increased proliferation cells, high incidence malignancies, more metastases, and generally poor prognosis for patient. The research sought assess effect silver nanoparticles reduced with ethyl cellulose polymer (AgNPs-EC) on TNF-α MCF-7 human breast cells.The AgNPs-EC were produced using green...
Graphical abstract
Cancers are regarded as hazardous due to their high worldwide death rate, with breast cancer (BC), which affects practically all patients globally, playing a significant role in this statistic. The therapeutic approach for BC has not advanced using standard techniques, such specialized naringin (NG) chemotherapy. Instead, novel strategy been utilized enhance smart drug delivery (SDD) tumors.
Targeting of G-protein coupled receptors (GPCRs) like somatostatin-14 (SST-14) could have a potential interest in delivery anti-cancer agents to tumor cells. Attachment SST different nano-carriers e.g. polymeric nanoparticles is limited due the difficulty interaction between itself and those nano-carriers. Furthermore, instability problems associated with final formulation. Attaching gold (AuNPs) using positive negative charge citrate-AuNPs be considered new technique get stable...
Urinary catheter infections remain an issue for many patients and can complicate their health status, especially individuals who require long-term catheterization. Catheters be colonized by biofilm-forming bacteria resistant to the administered antibiotics. Therefore, this study aimed investigate efficacy of silver nanoparticles (AgNPs) stabilized with different polymeric materials generated via a one-step simple coating technique ability inhibit biofilm formation on urinary catheters. AgNPs...
Breast cancer (BC) is the most common malignancy in women globally. Significant progress has been made developing structural nanoparticles (NPs) and formulations for targeted smart drug delivery (SDD) of pharmaceuticals, improving precision tumor cell targeting therapy.
Bacterial infections caused by different strains of bacteria still one the most important disorders affecting humans worldwide. Polymers nanocomposite systems could be considered as an alternative to conventional antibiotics eradicate bacterial infections.In attempt enhance antibacterial performance silver and iron oxide nanoparticles, decrease their aggregation toxicity, a polymeric hybrid system combining both nanoparticles is produced.Magnetic Ag-Fe3O4@polymer nanocomposites prepared...
Tumor necrosis factor (TNF-α) and inflammatory cytokine (IL-6) play a vital role in various cellular incidents such as the proliferation death of cells during carcinogenesis. Hence, regulation these biomarkers could be promising tool for controlling tumor progression using nanoformulations. Silver nanoparticles-poly (vinyl pyrrolidone) (AgNPs-PVP) were prepared reduction silver nitrate stabilized with PVP. They are characterized through yield percentage, UV-VIS, FT-IR, size, charge,...
The topical delivery of therapeutics is a promising strategy for managing skin conditions. Cyclooxygenase-2 (COX-2) inhibitors showed possible target chemoprevention and cancer management. Celecoxib (CXB) selective COX-2 inhibitor that impedes cell growth generates apoptosis in different tumors. Herein, an investigation proceeded to explore the usefulness nano lipid vesicles (transethosomes) (TES) CXB permit penetration considerable quantities drug curing cancer. prepared nanovesicles were...