A5024452011- Nanoparticles: synthesis and applications
- Wound Healing and Treatments
- Nanoparticle-Based Drug Delivery
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Cancer Research and Treatments
- Advancements in Transdermal Drug Delivery
- Food Science and Nutritional Studies
- Advanced Drug Delivery Systems
- Bee Products Chemical Analysis
- Pharmacology and Obesity Treatment
- Medicinal Plants and Neuroprotection
- Ziziphus Jujuba Studies and Applications
- Carbohydrate Chemistry and Synthesis
- Phytochemicals and Medicinal Plants
- Essential Oils and Antimicrobial Activity
- Nanocomposite Films for Food Packaging
- Natural Antidiabetic Agents Studies
- Computational Drug Discovery Methods
- Advanced biosensing and bioanalysis techniques
- Proteoglycans and glycosaminoglycans research
- Hedgehog Signaling Pathway Studies
- Electrospun Nanofibers in Biomedical Applications
- Saffron Plant Research Studies
- Silk-based biomaterials and applications
University of Sadat City
2021-2025
Nahda University
2019
The aim of this study was to formulate a hydrogel loaded with polymeric nanoparticles (PoNPs) simvastatin (SIM) for topical wound healing application.The SIM PoNPs were prepared by using the nanoprecipitation method improve drug solubility and skin permeation. Furthermore, content, solubility, particle size, surface charge, transmission electron microscopy evaluated. Then, on hydrogel, physical characteristics, in vitro release, ex vivo permeation Finally, gel applied rat wounds,...
Cancer is one of the leading causes death worldwide. In many cases, cancer related to elevated expression a significant cytokine known as tumor necrosis factor-α (TNF-α). Breast in particular linked increased proliferation cells, high incidence malignancies, more metastases, and generally poor prognosis for patient. The research sought assess effect silver nanoparticles reduced with ethyl cellulose polymer (AgNPs-EC) on TNF-α MCF-7 human breast cells.The AgNPs-EC were produced using green...
Silver nanoparticles (G-AgNPs) improve wound healing by promoting skin cell proliferation and differentiation. Therefore, G-AgNPs could act as drug carriers healers in biomedicine. The current study aimed to using natural, safe G-AgNPs.The were reduced with ethylcellulose (EC) incorporated into an oil-in-water cream base. size, charges, wavelength used characterize the prepared G-AgNPs. Further, transmission electron microscope (TEM) scanning (SEM) provide shape of Moreover, was evaluated...
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Abstract Wound healing is a critical process essential for the body’s recovery from injuries, often complicated by bacterial infections. Silver nanoparticles (AgNPs) have gained attention due to their antibacterial and tissue-regenerative properties. However, conventional chemical synthesis methods AgNPs pose environmental risks. This study utilizes Ziziphus spina-christi (ZSC) extract eco-friendly of AgNPs, evaluating wound-healing capabilities. The AgNPs-ZSC showed an absorption maximum at...
The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has opened the door to potential threats of system. discovery drugs from natural sources is one most important strategies for treating upper tract. In this study, we investigated selected formulated EOs activities against Gram-negative (E. coli, K. pneumonia, and P. aeruginosa) Gram-positive (S. aureus, E. fecalis) bacteria SARS-CoV-2 virus, with mode action as anti-SARS-CoV-2. Cinnamomum zeylanicum...
Abstract Sorafenib (SFB) is an anticancer drug with sparingly water solubility and reduced bioavailability. Nanoformulation of SFB can increase its dissolution rate solubility. The current study aimed to formulate in nanoparticles improve their sorafenib (SFB-PNs) were synthesized using the solvent evaporation method, then evaluated for particle size, polydispersity index (PDI), zeta-potential, morphological structure, entrapment efficiency (EE%). Further, efficacy A549 Michigan Cancer...
Eco-friendly synthesis of silver nanoparticles (SN) by using a naturally occurring plant, such as Nitrosalsola (Salsola) vermiculata (SV), could be novel way for appropriate wound healing. AgNO3 was reduced SV to produce safe SN (SN-SV) extract and hasten the healing process. The obtained SN-SV were characterized size, charge, wavelength, surface morphology. optimized formulation dispersed in O/W cosmetic cream. Then, it terms pH, viscosity, homogeneity, permeability. ex vivo studies have...
Obesity has become a prevalent issue worldwide, leading to various complications such as hyperlipidemia, diabetes, and cardiovascular problems. Statins, FDA approved anti-hyperlipidemic drugs, still pose some concerns upon their administration. Recently, researchers have looked for natural products an alternative manage hyperlipidemia obesity.
Itraconazole (ITZ) is an antiangiogenic agent recognized as a potent suppressor of endothelial cell growth that suppresses angiogenesis. Nevertheless, its exploitation significantly restricted by low bioavailability and systematic side effects. The objective this study was to utilize glycerosomes (GLY), glycerol-developed vesicles, innovative nanovesicles for successful ITZ pulmonary drug delivery.
Cetuximab (CTX) is known to have cytotoxic effects on several human cancer cells in vitro. However, CTX poorly water soluble and need an improved formulations can reach at high concentrations with low side effects. We developed polymeric nanoparticles (PEGNPs) loaded evaluated their vitro cytotoxicity anticancer properties against lung (A549) breast (MCF-7) cells. CTX-PEGNPs were formulated using the solvent evaporation technique, morphological evaluated. Further, of cell viability MTT assay...