A5052994050- Tracheal and airway disorders
- Computational Drug Discovery Methods
- Alzheimer's disease research and treatments
- Voice and Speech Disorders
- DNA and Nucleic Acid Chemistry
- Bioinformatics and Genomic Networks
- HIV Research and Treatment
- Lung Cancer Treatments and Mutations
- Advanced biosensing and bioanalysis techniques
- Chronic Myeloid Leukemia Treatments
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- RNA Interference and Gene Delivery
- Chronic Lymphocytic Leukemia Research
- BRCA gene mutations in cancer
- Cancer Genomics and Diagnostics
- Airway Management and Intubation Techniques
- DNA Repair Mechanisms
University of Southern California
2024
University of Cincinnati Medical Center
2019-2020
Cincinnati Children's Hospital Medical Center
2019
Sanford Consortium for Regenerative Medicine
2018
University of California, San Diego
2018
National Institute of Allergy and Infectious Diseases
2015
National Institutes of Health
2015
Objectives Subglottic stenosis (SGS) is the most common type of laryngeal in neonates. SGS severity currently graded based on percent area obstruction (%AO) via Myer‐Cotton grading scale. However, patients with similar %AO can have widely different clinical courses. Computational fluid dynamics (CFD) patient‐specific imaging quantify relationship between airway geometry and flow dynamics. We investigated effect axial position work breathing (WOB) neonates using magnetic resonance imaging....
Abstract Accurate estimation of carrier probabilities cancer susceptibility gene mutations is an important part pre-test genetic counselling. Many predictive models are available but their applicability in the Asian population uncertain. We evaluated performance five BRCA mutation risk a Chinese cohort 647 women, who underwent germline DNA sequencing panel. Using areas under curve (AUCs) on receiver operating characteristics (ROC) curves as measures, did comparably well western cohorts...
A DNA four-way junction device capable of expansion and contraction cycles using an inosine-based partial strand displacement scheme is reported. These nanoscale positioning capabilities are used to provide on-demand activation deactivation a pair split E6 DNAzymes on the device. The also demonstrates combined catalytic rate significantly higher than original DNAzyme under similar operational conditions. This approach can structural organization spatially control other multicomponent...